Body weight > 30 kg
Weight ? 35 kg
DONOR: Weight >= 20 kg and patient or guardian able to provide consent
DONOR: Donors who are not expected to meet the minimum target dose of marrow cells (1 x 10^8 nucleated cells/kg recipient ideal body weight)
Adequate renal function with normal serum creatinine, or if creatinine above or below institutional normal range, a calculated glomerular filtration rate of ? 50 mL/min/1.73m2 (e.g., as calculated by the Cockcroft Gault formula) using actual body weight; if subject has body mass index > 30 kg/m2, lean body weight must be used.
In the haplo cohort, the weight of the haplo donor must be ? 20 kg.
Weight ? 35 kg
DONOR: Age >= 4 and weight of >= 15 kg
Patients who are 20% below their ideal body weight
Patient weight >= 100 kg; patients >= 70 kg with MUDs must be discussed with the principal investigator
DONOR: weight of at least 35 kg
An actual body weight > 40kg
Has a body weight ? 40kg at the time of enrollment
Body weight >= 30 kg.
Weight over 40 kilograms (kg)
STRATUM B: Must meet the following weight and body surface area (BSA) restrictions:\r\n* For enrollment on dose level 0A, must have a weight  >= 16kg and < 32kg\r\n* For enrollment on dose level 0B must have a weight >= 32kg and BSA >= 0.55m^2\r\n* For enrollment on dose level 1, must have a weight >= 16kg and BSA >= 0.55m^2\r\n* For enrollment on dose level 2, must have a weight >= 16kg and BSA >= 0.63m^2\r\n* For enrollment on dose levels 3 or 4A, must have a weight >= 16kg \r\n* For enrollment on dose levels 4B or 5, must have a weight >= 20kg and =< 106kg
Body weight < 50 kilograms (110 pounds) or a body mass index ? 35 kg/m2.
Body weight > 30 kg.
Body weight > 30 kg
Patient body weight must be above the minimum necessary for the patient to receive the ONC201 dose indicated for the currently enrolling dose level. The minimum body weight ranges from 10 to 35kg depending on the dose level.
Body weight of greater than or equal to (>=) 39 kilogram (kg) at Screening
Body weight > 30 kg
Body weight > 35 kg
Body weight > 30 kg
Weight < 30 kg
Body weight of at least 40 kilograms
DONOR: At least 40 kilogram body weight
CELL PROCUREMENT: Pediatric subjects (weight must be >= 10 kg)
Weight over 40 kg
Stable dose of corticosteroids for 2 weeks prior to enrollment, i.e. the patient’s steroid dose (mg/kg) will remain unchanged (e.g. 0.5 mg/kg) in the 2 weeks preceding enrollment; allowances will be made for up or down titrating the dose based on changes in body weight
DONOR: Weight > 35 kg
Significant weight loss (> 20% of body weight [BW]) within past 6 months prior to inclusion into the trial or actual body weight of less than 50 kg
Patients with body weight < 30 kg
Body weight > 30 kg
Weight > 30kg (required for flat dose-based administration of study agents)
PRIOR TO CELL PROCUREMENT: For pediatric subjects (weight must be ? 10 kg)
Weight ? 15 kg (33 lb)
Patients with a weight of < 39 kg
DONOR: Weight >= 40 kg
Weight > 50 kg
Body weight < 3 kg.
DONOR: Weight >= 40 kg
DONOR: Weight < 20 kg
In addition, each unit will have a cryopreserved dose of at least 1.5 x 10^7 total nucleated cells/recipient body weight (TNC/kg)
DONOR: Weight >= 20kg
Body weight of greater than or equal to (>=) 39 kilogram (kg) at Screening
Body weight of greater than 30 kg
Clearance to be calculated using Cockcroft formula: Males: 1.23 x (140 - age) x weight (kg) - serum creatinine (?mol/l) ; Females: 1.05 x (140 - age) x weight (kg) - serum creatinine (?mol/l)
For patients whose body weight exceeds ideal body weight (IBW) by more than 20%, adjusted body weight may be used for calculation of PBSC dose
Body weight > 30 kg
Body weight > 30 kg
DONORS: Body weight of at least 40 kilograms
Body weight < 40 kg
DONOR: At least 40 kilogram body weight
Weight >= 15 kg
Weight < 30 kg
Body weight < 40 kilograms
Body weight < 40 kilograms.
Body weight ? 175 kg.
(140 - age) x (weight in kg) x (0.85 if female)/ 72 x (serum creatinine in mg/dL)
Body weight > 30 kilograms.
Body weight > 30 kg
In the opinion of the investigator, patients who are significantly below their ideal body weight
Patients that in the opinion of the investigators are significantly below their ideal body weight
Current body mass index (BMI) >= 25 kg/m^2 and weight =< 400 lbs, and willing to lose > 5% of their body weight; NOTE: participants should not have weight loss greater than 5% of body weight in the last 6 months; all weights for determination of eligibility may be determined by self-reported of weight if not documented in the medical records; exceptions that are felt to be due to surgical or other procedures (e.g., mastectomies or reconstruction) may be allowed with prior approval of the Protocol Chair/designee
DONOR: Weight (Wt) > 25 kg
DONOR: At least 40 kilogram body weight
DONOR: Body weight of at least 40 kilograms
Body weight > 30 kg
Weight < 30 kg
Subjects with a body weight > 140 kg (for Cohorts dosing 20 mg/kg of ALXN1007 and higher only).
Weight of at least 10kg.
Weight between 40 kg and 180 kg
Weight >= 45 kg
Patients whom, in the opinion of the investigators, are significantly below their ideal body weight
Body weight >= 45 kilogram (kg) and a body mass index >= 19 kilogram per squaremeter (kg/m^2)and <40 kg/m^2 (inclusive);
In the opinion of the investigator, patients who are significantly below their ideal body weight
Weight ?3rd percentile for age and gender (and ?3.0 kg)
In the opinion of the investigator, patients who are significantly below their ideal body weight.
Patients who are 13 years old or older and have more than 45 kg of body weight will be eligible after consultation with their pediatric attending
Body weight < 35 kg (77 pounds)
Weight ? 34 kg.
Body weight > 30 kg
Body weight > 150 kg
Weight >= 45 kg
Weight > 10 kg (22 lbs)
Patient weight >= 50 kg
Obesity (body weight > 140 Kg)
Body weight must be >= 20 kilograms (kg) if suspension is not available
Weight > 110kg
weight of less than or equal to 45 kg (for sites using cefuroxime only).
Weight between 50 kg to 130 kg
Patient weight at least 3.3 kg.
Body weight > 30 kg
Normal weight (BMI < 25.0 kg/m^2)
Body weight between 50 kg (110 lb) and 110 kg (243 lb), inclusive
Body weight greater than 350 lbs (158 Kg)
Body weight > 137 Kg (300 lbs)
Body weight greater than 350 lbs (158 Kg)
Unexplained change in weight (> 4.5 kg) within the past 6 months