NOTE: Patients with documented bone marrow involvement by lymphoma are not required to meet the above hematologic parameters, but must have a platelet count of at least 75,000/mcL and neutrophil count of at least 1,000/mcL
Platelet count >= 100,000/mcL
Platelet count > 100,000/mcl
Platelet count > 50 k/mcL
Platelet count > 100,000 cells/mcL
Platelet count >= 75,000/mcL
Platelet count >= 100,000/mcL
Platelets ?100,000/mcL (non-transfused platelet count)
Platelet count >= 100,000/mcL
Platelet count >= 100,000/mcL, within 16 days of starting therapy
Platelet < 100,000/mcL
Platelet count >= 100 k/mcl, obtained within 7 days prior to first study treatment
Thrombocytosis defined as platelet count > 1,200,000/mcL
Platelet >= 100,000 / mcL
Platelet count >= 75000/mcL
Platelet count >= 100,000/mcL
PHASE II: Platelet count >= 100,000/mcL
Platelet count >= 75,000/mcL
Platelet count >= 100,000/mcL
Patients with adequate organ function, reflected by the following parameters: WBC ? 3000/mcl Absolute neutrophil count (ANC) ? 1500/mcl Platelet count ? 100,000/mcl SGOT, SGPT, and alkaline phosphatase ? 2.5 X upper limit of normal (ULN) Bilirubin ? 1.5 X ULN Creatinine ? institutional ULN
Platelet > 50,000 mcL
Platelet count < 75 K/mcL
Relapsed/refractory MCL: Platelet count >= 30,000/mm^3 (transfusion to reach platelet count allowed); (patients who have bone marrow infiltration by MCL are eligible if their platelet level is equal to or > than 15,000/mm^3; these patients should be discussed with either the PI or Co-PI of the study for final approval)
Newly diagnosed MCL: Platelet count > 50,000/mm^3; patients who have bone marrow infiltration by MCL are eligible if their platelet level is equal to or > than 15,000 /mm^3; (platelet transfusions are allowed; these patients should be discussed with either the PI or Co-PI of the study for final approval)
Platelet count > 100,000/mcL
Platelet count > 80,000/mcL
Platelet count >= 100,000 cells/mcL
Platelet count < 50 K/mcL at time of enrollment
Platelet count > 50,000 cells/mcL (50 × 10^9/L)
Platelet count >= 75,000/mcL
Platelet count >= 100,000/mcl
Platelet count >= 100 K/mcL
Platelet count >= 50,000/mcL
Platelet count >= 100,000/mcL
Platelet count >= 100,000/mcl
Platelet count of at least 100,000 per mcL
Platelet count >= 100,000/mcL
Most recent platelet count prior to surgery < 70,000/mcl
Platelet count > 100,000/mcL
Thrombocytopenia:\r\n* Defined as platelet count < 100,000/mcL\r\n* The patient will have had at least 2 complete blood counts (CBC) with platelet counts < 100,000/mcL separated by at least 4 weeks, and no platelet count >= 100,000/mcL in the prior 6 week period, despite (1) delay or (2) modification of chemotherapeutic regimen\r\n* A platelet count of > 100,000/mcL, that follows within 7 days of a platelet transfusion, will not make the patient ineligible, as long as one or more subsequent platelet counts confirms thrombocytopenia (< 100,000/mcL)\r\n* Patients have undergone bone marrow aspirate and biopsy, or peripheral blood test in the prior 3 months, without evidence of leukemia or myelodysplasia by fluorescent in situ-hybridization (FISH)\r\n* Dysplastic changes, based on morphology only, will not exclude the patient if FISH panel for myelodysplastic syndrome (MDS) is normal
Platelet count >= 100,000/mcL
Platelet count >= 50,000/mcL
Platelet count <75,000/mcL.