Total bilirubin (T. bili) =< 1.3
Total bilirubin ?2.0
Obtained =< 21 days prior to registration: total bilirubin =< 2.0 mg/dL (if total is elevated check direct and if normal patient is eligible)
Obtained =< 21 days prior to registration and confirmed prior to the first dose of study drug: Total bilirubin =< 1.5 mg/dL (if total is elevated check direct and if normal patient is eligible)
Total bilirubin ? 2
RETREATMENT WITH MODIFIED T-CELLS INCLUSION CRITERIA: Total bilirubin: =< 3 x ULN for age OR conjugated bilirubin =< 2 mg/dL
Performed within 10 days of treatment initiation: Serum total bilirubin ? 1.2 X ULN OR in case of Gilbert’s disease an elevated total bilirubin is allowed if direct bilirubin is ? 40% of total
Total bilirubin < 2.0
Total bilirubin =< 2.5 x normal prior to biopsy
Total bilirubin > 5
Total bilirubin =< 1.5 upper limit of normal unless the patient is receiving a protease inhibitor known to be associated with increased bilirubin (e.g. atazanavir), in which case total bilirubin =< 7.5 mg/dL with direct fraction =< 0.7
Bilirubin (total) < 2.0 ml/dl within 14 days of study entry
ELIGIBILITY CRITERIA FOR T-CELL PRODUCT INFUSION: Total bilirubin: =< 3 x ULN for age OR conjugated bilirubin =< 2 mg/dL
RETREATMENT WITH MODIFIED T CELLS: Total bilirubin: =< 3 x ULN for age OR conjugated bilirubin =< 2 mg/dL
Total bilirubin =< 3
Total bilirubin less than or equal to 1.5 x normal for age
Total bilirubin =< 3.0
Total bilirubin < 3.0 mg/dl (if total bilirubin is >= 3.0 patient is eligible if direct bilirubin is within normal limits)
Total bilirubin =< 3.0
Total bilirubin less than or equal to 1.5
Total bilirubin less than or equal to 3.0
Total bilirubin =< 3.0
Total abstinence or
Total bilirubin =< 2x normal
Total bilirubin < 1.5 x normal
Serum total bilirubin =< 1.2 X ULN OR in case of Gilbert’s disease an elevated total bilirubin is allowed if direct bilirubin is =< 40% of total, should be performed within 10 days of treatment initiation
Total bilirubin within the reference range during screening evaluation
Total bilirubin within institutional normal range
Total bilirubin =< 1.5 x normal for age
Total bilirubin =< grade 1\r\n* Note: If total bilirubin is 2 to 3 mg/dL, but direct bilirubin is normal, then the patient will be considered eligible
Total serum bilirubin =< 1.5 x ULN\r\n* NOTE: if total bilirubin is 2-3 mg/dL, but direct bilirubin is normal, then the patient will be considered eligible
Total bilirubin up to 1.5 X institutional normal reference range
Total bilirubin ? 2 times ULN            \r\n* Patients with documented diagnosis of Gilbert syndrome resulting in elevated total bilirubin levels will be eligible, provided all other eligibility criteria are met\r\n* Patients with a total bilirubin of 2-3 mg/dL and direct (conjugated) bilirubin in the normal range will be eligible, provided all other eligibility criteria are met
Total bilirubin < 1.5
Total abstinence or;
Total bilirubin =< 1.5 mg/dL (if total is elevated check direct and if normal patient is eligible), obtained =< 21 days prior to registration and confirmed prior to the first dose of study drug
Obtained =< 21 days prior to registration: Total bilirubin =< 2.0 mg/dL (if total is elevated check direct and if normal patient is eligible)
Total bilirubin normal;
Total bilirubin =< grade 3
Total bilirubin < 2.0
Total bilirubin =< 2.5 x normal prior to biopsy
Total bilirubin =< 2.0
Total bilirubin =< 3.0
Total bilirubin =< 2.0 mg/dL obtained =< 14 days prior to registration (if total is elevated check direct and if normal patient is eligible)
Total bilirubin =< 1.5
Total bilirubin =< 2
Total bilirubin should be =< 1.5 x upper limit of normal (ULN); if, however, the elevated bilirubin is felt to be secondary to atazanavir therapy, participants will be allowed to enroll on protocol if the total bilirubin is =< 3.5 mg/dL provided that the direct bilirubin is normal
Total bilirubin ? 1.5 times the upper limit of normal (ULN); for patients with hepatocellular carcinoma only, total bilirubin ? 3 mg/dL (i.e. Child-Pugh Score for bilirubin is no greater than 2).
Normal total serum bilirubin
Total bilirubin < 1.5 x ULN for age or normal conjugated bilirubin
Total bilirubin 1.5 x normal for age, AND
Total bilirubin < 2.0
Total bilirubin =< 2.0
Total bilirubin =< 1.5 x normal
Total bilirubin =< 2.0, within 30 days prior to enrollment
Total bilirubin >1.8, creatinine >2, hemoglobin <10, platelets <50,000, WBC <2,000)
Total bilirubin >1.5, creatinine >2, hemoglobin <10, platelets <50,000, WBC <2,000
Total bilirubin < 3.0