Patients with a history of uncontrolled seizure disorder; including focal or generalized seizure may not have had a seizure within one year prior to registration
Seizure disorders requiring anticonvulsant therapy.
Documented history of or current brain metastases due to seizure risk
Contraindication to the use of bupropion including seizure disorder or conditions that increase the risk of seizure (including bulimia and/or anorexia nervosa, central nervous system [CNS] tumor, severe stroke, abrupt withdrawal from benzodiazepines or alcohol)
Known brain metastases or history of seizure
Patients with active seizure or history of seizure are not eligible
Have a history of a seizure
Seizure disorders requiring anticonvulsant therapy.
Past or current history of epilepsy or seizure disorder; exception: well-documented febrile seizure of childhood
Known central nervous system (CNS) metastases or seizure disorder; patients with known brain metastases that have been successfully treated and stable for >= 6 months without requirement for corticosteroids and without seizure activity will be eligible
Inadequate seizure control
Patients with active seizure or a history of seizure are not eligible
Patients must NOT have active seizure(s) or history of seizure(s)
PHASE II: Patients must NOT have active seizure(s) or history of seizure(s)
Patients with a history of seizure disorder requiring antiepileptics who have had a seizure episode within the last 6 months
Patients with history of seizure disorder requiring antiepileptics who have had a seizure episode within the last 6 months
For Cohort C: Has a history of seizure or any condition that may predispose to seizure
Patients must not have active seizure or history of seizure
Subject has a history of seizure or any condition that may predispose to seizure.
History of seizure or any condition that may predispose to seizure;
A history of seizure within 12 months prior to study entry.
Has a history of seizure
History of seizure or any condition or concurrent medication that may predispose to seizure
Concurrent therapy with medications known to have seizure potential
History of seizure or any condition or concurrent medication that may predispose to seizure
past history of seizure due to any cause except a single febrile seizure in childhood. Patients with a history of seizures should not have had a seizure within 12 months of Screening and must have had no anticonvulsants for 12 months prior to Screening,
Subject has a history of seizure within the past 12 months of Screening as assessed by neurology examination and history.
History of seizure or condition that may pre-dispose to seizure
Any history of seizure or condition that may predispose to seizure
Patients with uncontrolled seizure disorders
No uncontrolled seizure disorders
Patients must not have a history of any type of seizure for at least 10 years prior to registration.
Concurrent treatment with medications known to have seizure potential
History of seizure or condition that may predispose to seizure
Patients must not have uncontrolled central nervous system disease; patients with a history of seizure disorders must be seizure-free for one year prior to enrollment
Known brain metastases, uncontrolled seizure disorders, encephalitis, or multiple sclerosis
History of seizure or any condition that may predispose to seizure.
Seizure disorders requiring anticonvulsant therapy
History of seizure disorders
Any history of brain metastases or prior seizure or conditions predisposing to seizure activity
Focal or generalized seizure within the last 12 months.
Uncontrolled seizure activity.
History of seizure
Prior seizures < 3 months prior to enrollment. Subjects with a history of seizure disorders ? 3 months prior to enrollment must be seizure free and on stable anticonvulsant medication(s) for ? 3 months prior to enrollment).
Subjects with uncontrolled seizure
Seizure disorders
History of a seizure disorder diagnosis or have experienced a seizure in the past 12 months
PATIENTS: History of neuroleptic malignant syndrome or active seizure disorder (with seizure episode within the past week)
Patient has an active seizure disorder; (patients with a previous history of seizure disorders will be eligible for the study, if they have had no evidence of seizure activity, and they have been free of anti-seizure medication for the previous 5 years)
Survivors who report ever being diagnosed with a seizure disorder or have experienced a seizure in the past 12 months will be excluded
Patients who have a history of head injury or who have known seizure activity
Patients with seizure disorders treated with anticonvulsants
Patients who have a history of head injury or who have known seizure activity.
Any history of brain metastases or prior seizure or conditions predisposing to seizure activity
Documentation of history of seizure within previous 5 years
Patients with prior seizure history who have experienced a seizure within the three months prior to enrollment are excluded
Patients receiving glucocorticoids and/or anti-seizure medications are eligible for this study
Patients with a seizure history will not be permitted on protocol; patients on anticonvulsant medications will not be permitted on study