Patients who are on hemodialysis.
Requirement for hemodialysis or peritoneal dialysis
Patients receiving hemodialysis or peritoneal dialysis
Patients who require hemodialysis
Estimated creatinine clearance < 30 mL/min or use of renal replacement therapy (e.g., hemodialysis, continuous renal replacement therapy, peritoneal dialysis) within 7 days prior to Day 1
Receiving renal replacement therapy, hemodialysis, or peritoneal dialysis
Renal failure requiring peritoneal dialysis or hemodialysis
Renal failure requiring hemodialysis or peritoneal dialysis
REGORAFENIB EXCLUSION CRITERIA: Renal failure requiring hemodialysis or peritoneal dialysis
Patients who are on hemodialysis
Patients who are on hemodialysis
Severe renal insufficiency (estimated creatinine clearance <20 mL/min) or on hemodialysis at the time of randomization or likely to require dialysis during the study.
Patients who are on hemodialysis.
Patients who are on hemodialysis
Expected requirement for hemodialysis while on study therapy
Patients requiring hemodialysis
Renal insufficiency requiring hemodialysis or peritoneal dialysis
Patients who are on hemodialysis.
Renal failure requiring hemodialysis or peritoneal dialysis
Requirement for hemodialysis or peritoneal dialysis
Patients on hemodialysis
e. Renal failure needing hemodialysis or peritoneal dialysis
Patients who are on hemodialysis.
Expected requirement for hemodialysis while on study therapy
Serum creatinine level > 1.5 x the upper limit of normal (ULN), chronic renal failure requiring hemodialysis or peritoneal dialysis.
Subjects on hemodialysis or peritoneal dialysis
Serum creatinine will not be used to exclude patients; patients on renal-replacement therapy (e.g., hemodialysis or peritoneal dialysis) will be eligible to participate
Subjects who require routine/intermittent hemodialysis or continuous peritoneal dialysis (due to inability to provide appropriate dosing schedule for oseltamivir) at Baseline. CRRT modalities are allowed.
Renal failure requiring hemodialysis or peritoneal dialysis.
Renal failure requiring hemodialysis or peritoneal dialysis
Receiving renal replacement therapy, hemodialysis, or peritoneal dialysis
Patient is not currently on hemodialysis and/or peritoneal dialysis for management of chronic kidney disease or acute failure/conditions.
Subjects currently receiving hemodialysis
Stage 5 chronic kidney disease or need for hemodialysis
Oliguric acute renal failure (urine output < 500 ml/day) unless already on hemodialysis
Presence of significant renal disease or hemodialysis which would result in dramatic reductions of systemic levocarnitine levels
Patients on hemodialysis