Patients who have had significant traumatic injury within 28 days prior to enrollment are not eligible
No major surgical procedure or significant traumatic injury within 6 weeks prior to study registration, and must have fully recovered from any such procedure.
Significant traumatic injury within 3 weeks prior to planned initiation of study therapy
Major surgical procedure or significant traumatic injury within 28 days prior to study enrollment
Traumatic injury within 2 weeks before initiation of study treatment
Major surgical procedure or significant traumatic injury within 28 days before start of study registration
Traumatic injury or palliative radiotherapy within 2 weeks prior study treatment initiation
Patients who have had major surgical procedures or significant traumatic injury within 28 days prior to study treatment
Patients who have had a major surgical procedure within 14 days of randomization. Patient has significant traumatic injury within 28 days before randomization.
Stem cell infusion without traumatic brain injury
Major surgical procedure or significant traumatic injury within 28 days prior to study drug administration.
Major surgical procedure or significant traumatic injury within 28 days before start of study medication
Major surgical procedure or significant traumatic injury within 28 days before start of study medication
Or a traumatic brain injury will be excluded
Invasive surgical intervention (including biopsy by surgical route), major traumatic injury during the 28 days prior to the start of treatment, or scheduled invasive surgical intervention during the study treatment
Significant traumatic injury within the past 4 weeks.
Major surgical procedure or significant traumatic injury within 28 days prior to study drug administration
Patients are excluded if they have had a surgical procedure or a significant traumatic injury within 28 days prior to randomization
Have had a major surgical procedure or significant traumatic injury including nonhealing wound, peptic ulcer, or bone fracture ?28 days prior to randomization.
Have a history of traumatic or surgical castration
Major surgical procedure or significant traumatic injury within 4 weeks prior to first dose of study treatment
history of traumatic brain or head injury with loss of consciousness
Major surgical procedure (including craniotomy) or significant traumatic injury less than 28 days or those who receive minor surgical procedures (e.g. core biopsy or fine needle aspiration) within 7 days
Major surgical procedure or significant traumatic injury, radiotherapy, chemotherapy, targeted therapy, hormone therapy, or other anticancer therapy.
Major surgical procedure or significant traumatic injury, as defined by the site investigator, within 28 days before study registration.
Major surgical procedure or significant traumatic injury within 28 days before start of study medication
Significant traumatic injury within 3 weeks prior to initiation of study treatment
Significant traumatic injury within 4 weeks before Cycle 1, Day 1
Patients with a history of traumatic brain injury prior to tumor diagnosis are not eligible
Significant traumatic injury or major surgical procedure within 4 weeks prior to starting study treatment
History of brain injury that significantly impacted cognition; as indicated responses on the Ohio State University Traumatic Brain Injury Identification Method (OSU TBI-ID) greater or equal to any of the following: 30 minutes or more of loss of consciousness (LOC), two or more mild cases within two weeks of each other, or any injury with loss of consciousness before the age of 15
Major surgical procedure or significant traumatic injury within 28 days before start of study medication
Major surgical procedure, traumatic injury, non-healing wound, or peptic ulcer ?28 days prior to randomization.
Any past neurologic insult that is known to affect brain function such as traumatic brain injury, dementia, encephalopathy, etc.
Participant has a history of neurologic event (i.e. traumatic brain injury) unrelated to cancer or its treatment
History of traumatic brain injury
With history of a neurological disorder, neurodegenerative disease, or traumatic brain injury with loss of consciousness (> 60 minutes), as per medical records or patient report
Known history of cerebrovascular disease, dementia or prior non-mild traumatic brain injury
Major surgical procedure or significant traumatic injury within 6 weeks prior to study registration or not fully recovered from any such procedure