Cluster 196: benefit standard therapy available clinical solid advanced convey metastatic histologically 
Cluster 746: standard therapy progressed exists advanced intolerant solid metastatic tumors patients 
Cluster 1441: solid histologically cytologically confirmed tumor advanced standard metastatic diagnosis tumors 
Cluster 1987: tumors solid advanced patients malignant metastatic subjects eligible excluded cell 
Cluster 2448: standard therapy advanced refractory solid available metastatic histologically tumors tumor