Cluster 234: biopsy bronchoscopic accessed percutaneous thoracoscopic safely perspective undergo willingness waived Cluster 516: biopsy tumor accessible undergo patients amenable core biopsies treatment tissue Cluster 538: needle biopsy core fine aspiration fna breast diagnosis tumor invasive Cluster 1108: tumor primary brain patients biopsies positive biopsy metastatic diagnosis resection Cluster 2430: undergo willing biopsy biopsies tumor willingness treatment able pre research