Cluster 75: reversible effects recovered toxicity grade fully failure prior chemotherapy therapy 
Cluster 150: alopecia grade excluding recovery prior recovered neuropathy effects adverse toxicity 
Cluster 345: toxic effects recovered fully entering acute prior chemotherapy immunotherapy radiotherapy 
Cluster 745: toxic grade effects resolution alopecia acute prior therapy resolved neuropathy 
Cluster 1497: toxicities recovered grade therapy prior reversible chemotherapy effects previous alopecia 
Cluster 2373: recover reversible effects fully regardless failure acute interval prior chemotherapy 
Cluster 2492: toxic effects recovered therapy prior grade acute alopecia chemotherapy fully