Cluster 485: grade examination neuropathy peripheral pain clinical period screening patient initiation Cluster 898: higher neuropathy grade peripheral patients ctcae neurotoxicity current ii arm Cluster 1038: ctcae grade nci version neuropathy ongoing infection uln peripheral toxicity Cluster 1090: neuropathy peripheral grade enrollment patient days applicable ahct ctcae initiation Cluster 1722: grade neuropathy fl pain hypertriglyceridemia edema peripheral ae hyperglycemia low Cluster 2050: grades pain neuropathy significant grade days prior enrollment randomization day Cluster 2365: neuropathy grade baseline patients ctcae significant neurosensory time diabetic enrollment