Cluster 324: cypa grapefruit metabolized window predominantly narrow medications therapeutic hybrids star 
Cluster 575: ketoconazole itraconazole ritonavir clarithromycin telithromycin grapefruit voriconazole cypa inhibitors nelfinavir 
Cluster 615: ritonavir verapamil erythromycin inhibitors amprenavir ketoconazole cypa indinavir clarithromycin itraconazole 
Cluster 1288: inhibitors cypa boosted boceprevir telaprevir ritonavir cobicistat ciprofloxacin diltiazem olaparib