Cluster 127: likely interfere illness psychiatric participation medical clinical study patients opinion 
Cluster 236: subject study treatment protocol france investigator following french subjects condition 
Cluster 431: preclude participation investigator condition opinion medical study trial safe clinical 
Cluster 482: condition medical investigator opinion participation study interfere psychiatric protocol compliance 
Cluster 675: interfere cooperate likely deemed ability participate condition mental investigator sign 
Cluster 1594: coexisting likely condition medical procedures interfere results study psychiatric hazard 
Cluster 1665: results interfere interpretation medical likely participation laboratory investigator history including 
Cluster 1697: patient study investigator participate treatment disease medical therapy protocol unlikely 
Cluster 1735: extenuating circumstance significantly additional interfere opinion illness compliance condition medical 
Cluster 2181: psychological medical condition compliance investigator compromise participation social opinion study