Cluster 67: brain metastases steroids requiring symptomatic symptoms known control patients require 
Cluster 142: brain metastasis symptomatic steroids patients uncontrolled requiring escalating doses metastases 
Cluster 1560: leptomeningeal brain metastases disease symptomatic glucocorticoids uncontrolled continue treated require 
Cluster 1919: untreated brain metastases symptomatic known require symptoms control treated meningeal