Cluster 123: anc neutrophil absolute mm count peripheral randomization weeks cu days Cluster 240: cells platelet mm count marrow bone plasma nucleated plasmacytosis bil Cluster 475: cells neutrophil absolute count mm anc days registration bil prior Cluster 840: neutrophil mm absolute count greater cu days neutrophils hemoglobin inclusion Cluster 1226: neutrophil absolute anc count obtained registration days prior mm mcl