Cluster 608: platinum resistant disease based refractory progression months therapy sensitive ovarian Cluster 723: taxane chemotherapy prior anthracycline based received therapy regimen platinum metastatic Cluster 1092: platinum based chemotherapy regimen line disease received prior therapy progression Cluster 1333: regimen chemotherapy prior received treatment patients therapy disease based regimens Cluster 1388: anthracycline therapy prior received chemotherapy based containing exposure regimen patients