Cluster 452: absorption gastrointestinal affect condition interfere oral drug malabsorption medication significantly 
Cluster 899: gastrointestinal alter impairment absorption function significantly incidence disease metabolism rapamycin 
Cluster 954: metabolism outcomes dysfunction threatening absorption undue compromise safety organ interfere 
Cluster 1009: disorders absorption gastrointestinal interfere extensive drug study surgery medical history 
Cluster 2319: excretion metabolism distribution absorption interfere gastrointestinal significantly disease condition presence