The subject has tumor invading or encasing any major blood vesselsXx_NEWLINE_xXThe participant has tumor invading or encasing any major blood vesselsXx_NEWLINE_xXThe subject has tumor in contact with, invading or encasing any major blood vesselsXx_NEWLINE_xXThe subject has tumor in contact with, invading or encasing any major blood vesselsXx_NEWLINE_xXThe subject has tumor invading any major blood vesselsXx_NEWLINE_xXPatient�s baseline imaging must not indicate the presence of tumor invading or encasing any major blood vesselsXx_NEWLINE_xX