Karnofsky performance status >= 60 within 21 days prior to study entryXx_NEWLINE_xXKarnofsky performance status >= 60%Xx_NEWLINE_xXKarnofsky performance status >= 60%Xx_NEWLINE_xXTUMOR BIOPSY SEQUENCING: Karnofsky performance status >= 70%Xx_NEWLINE_xXTREATMENT: Karnofsky performance status >= 70%Xx_NEWLINE_xXKarnofsky performance status >= 70 within 28 days prior to step 2 registrationXx_NEWLINE_xXKarnofsky performance status >= 70%Xx_NEWLINE_xXKarnofsky performance status of >= 70 within 28 days prior to Step 2 registrationXx_NEWLINE_xXECOG performance status =< 2 (Karnofsky >= 60 %)Xx_NEWLINE_xXKarnofsky performance status >= 60%Xx_NEWLINE_xXKarnofsky performance status >= 60Xx_NEWLINE_xXKarnofsky performance score >= 70Xx_NEWLINE_xXKarnofsky performance status >= 60Xx_NEWLINE_xXHistory and physical exam, and Karnofsky performance status of >= 70 within 30 days prior to registrationXx_NEWLINE_xX