Alkaline phosphatase =< 2.5 x ULN (CTCAE v 3.0 grade 0-1)Xx_NEWLINE_xXAlkaline phosphatase within upper limits of institutional normal within 14 days prior to study entryXx_NEWLINE_xXAlkaline phosphatase less than or equal to 2.5 x ULN (CTCAE grade 1)Xx_NEWLINE_xXAlkaline phosphatase =< 3 x ULNXx_NEWLINE_xXAlkaline phosphatase =< 1.5 x IULN within 28 days prior to registrationXx_NEWLINE_xXSerum alkaline phosphatase (ALP) > 2 x ULNXx_NEWLINE_xXAlkaline phosphatase less than or equal to 2.5 x ULNXx_NEWLINE_xXAlkaline phosphatase =< 1.5 x institutional ULN, within 21 days prior to registrationXx_NEWLINE_xXAlkaline phosphatase (ALP) =< 2.5 x ULN measured within 28 days prior to randomizationXx_NEWLINE_xXPatients must have alkaline phosphatase =< 2.5 x IULN within 14 days prior to registrationXx_NEWLINE_xXAlkaline phosphatase =< 2 x ULN (=< 5 x ULN for patients with known liver involvement and =< 7 x ULN for patients with known bone involvement)Xx_NEWLINE_xXAlkaline phosphatase =< 2 x ULN (=< 5 x ULN for patients with known liver involvement and =< 7 x ULN for patients with known bone involvement)Xx_NEWLINE_xXWithin 6 weeks prior to randomization: Alkaline phosphatase must be =< 2.5 x ULN for the labXx_NEWLINE_xXAlkaline phosphatase =< 2.5 x ULN, within 14 days prior to registrationXx_NEWLINE_xXAlkaline phosphatase must be =< 3 x ULN for the lab within 28 days before randomizationXx_NEWLINE_xXAlkaline phosphatase =< 2.5 x ULN (=< 5 x ULN for patients with documented liver involvement or bone metastases)Xx_NEWLINE_xXAlkaline phosphatase =< 2 x IULNXx_NEWLINE_xXAlkaline phosphatase =< 2.5 x ULN (=< 5 x ULN for patients with documented liver involvement or bone metastases)Xx_NEWLINE_xXAlkaline phosphatase =< 2.5 x ULNXx_NEWLINE_xXAlkaline phosphatase =< 2.5 x ULNXx_NEWLINE_xXAlkaline phosphatase =< 2.5 x IULN, obtained within 28 days prior to step 2 registrationXx_NEWLINE_xXAlkaline phosphatase =< 2 x ULN (=< 5 x ULN for patients with documented liver involvement or bone metastases)Xx_NEWLINE_xX