History of allergy to study drug components History of allergy to study treatments or any of its components of the study arm that participant is enrolling Patients with a history of allergy to the study drug components are excluded Any history of allergy to the study drug components History of allergy to study drug components History of allergy to study drug components History of allergy or intolerance to study drug components or polysorbate-80-containing infusions History of allergy or hypersensitivity to study drug components History of allergy to study drug components. Any history of allergy to the study drug components Known allergy to the study drugs or any of its components Any history of allergy to the study drug components History of allergy or intolerance (unacceptable adverse event) to study drugs components. History of allergy to study drug components History of allergy to study drug components History of allergy to study drug components History of allergy or adverse drug reaction to study components History of allergy to study drug components History of allergy to components of nivolumab or DS-8273A, or known allergy to other antibody therapies History of sensitivity to any of the study medications, or components thereof or a history of drug or other allergy that, in the opinion of the investigator or Medical Monitor, contraindicates their participation. History of allergy to study drug components No contraindication to receiving radiotherapy and no known allergy to components of fresolimumab History of allergy to study treatments or any of its components of the study arm that participant is enrolling History of allergy to study drug components History of allergy or hypersensitivity to nivolumab components History of allergy to study drug components Known allergy to any of the treatment components Known allergy/hypersensitivity to drug or components History of allergy or hypersensitivity to nivolumab drug components. History of allergy or hypersensitivity to any of the study drugs or study drug components Any history of allergy to the study drug components History of allergy to study drug components. Local or severe allergy to any components of the drug regimen. Patient must not have a known allergy to any of the treatment components Subject has a history of allergy or hypersensitivity to study drug components; Have known allergy or hypersensitivity to any components of study treatment. History of allergy to components of ipilimumab or panobinostat, or known allergy to other antibody therapies Subject has a known allergy to ART-123 or any components of the drug product. Allergies and Adverse Drug Reaction: History of allergy to study drug components History of allergy to study drug components History of allergy or intolerance (unacceptable adverse event) to study drugs components Known allergy to any of the vaccine or adjuvant components, including eggs Known allergy or adverse drug reaction to nivolumab, or a history of allergy to study drug components Known allergy to any of the treatment components The patient has known allergy to any of the treatment components History of allergy to study drug components History of allergy to nivolumab components Known allergy to paclitaxel or any of its components The patient has a known allergy/history of hypersensitivity reaction to any of the treatment components. Allergy / history of hypersensitivity reaction to any of the treatment components History of allergy to study drug components History of known allergy to components of the study supplements Known allergy to any of the treatment components. Known allergy to any of the components of ATIR101 (e.g., dimethyl sulfoxide) Known allergy to any of the components of ATIR101 (e.g., dimethyl sulfoxide) Allergy to yeast or any of the components of Gardasil History of allergy to any of the components of OTL38, including folic acid History of allergy to any of the components of OTL38, including folic acid