Within 10 days of treatment initiation: Prothrombin time (PT) and partial thromboplastin time (aPTT) =< 1.5 X institutional upper limit of normal (IULN)
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x ULN
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 2 times normal; timeline: within 3 weeks prior to enrollment or
If requires pheresis to collect blood, prothrombin time (PT) < 1.5 upper limit normal
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 X upper limit of normal (ULN) unless receiving clinically indicated anticoagulant therapy
PART I: Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x the upper limits of normal
Normal prothrombin time (PT)
Normal prothrombin time (less than or equal to 15.2 seconds)
Prothrombin time (PT)/partial thromboplastin time (PTT) > 1.5 upper limit of normal (ULN)
Prothrombin time (PT)/partial thromboplastin time (PTT) less than 1.5 times normal
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x ULN
Prothrombin time (PT), partial thromboplastin time (PTT) =< 1.5 times upper limit of normal
Prothrombin time (PT) ?1.5 × ULN (Grade ?1).
Prothrombin time (PT) > 16.5 seconds or
Prothrombin time (PT) within normal limits (WNL)+/- 15 % unless on active anticoagulation obtained ? 14 days prior to randomization
Prothrombin time (PT)/partial thromboplastin time (PTT) ? 1.5 times the ULN
Prothrombin time (PT) no more than 2 seconds above the upper limits of normal (ULN)
Within 7 days (+ 3 day window) of enrollment: Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x the institutional upper limit of normal (ULN), (this will not apply to subjects with confirmed Factor XII deficiency)
Prothrombin time (PT) and partial thromboplastin time (PTT) must be =< 2 x the upper limit of the institution's normal range, at the time of enrollment
Obtained =< 28 days prior to registration: Prothrombin time (PT) =< 1.5 x upper limit of normal (ULN) unless patient is receiving anticoagulant therapy and PT or partial prothrombin time (PTT) is within therapeutic range of intended use of coagulants
Prothrombin time (PT) < 1.5
Hepatic: Total bilirubin 1.5 x ULN; transaminases ? 2.5 x ULN (may be up to 5 x ULN if clearly due to liver metastases); prothrombin time (PT) and partial thromboplastin time (PTT) < 2 x (ULN).
A Prothrombin Time (PT) or Partial Thromboplastin Time (PTT) within normal range
Prothrombin time (PT) =< 1.5 x ULN
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x ULN
Obtained within 14 days prior to registration; prothrombin time and partial thromboplastin time (PT / PTT) ? 50% increase from institutional ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) > 50% of deviation of institutional ULN
Prothrombin time (PT) or partial thromboplastin time (PTT) < 1.5 x upper limit of normal (ULN)
Prothrombin time (PT) < 1.5
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x ULN after correction of nutritional deficiencies that may contribute to prolonged PT/PTT
No baseline prothrombin time (PT)/partial thromboplastin time (PTT) abnormalities, coagulopathies, or who are on any blood thinners
Prothrombin time =< 1.5 x upper limit of normal (ULN) obtained within 14 days of first treatment
Prothrombin time (PT) =< 1.5 x ULN
Prothrombin time (PT) =< 1.5 x institutional upper limit of normal (ULN)
Prothrombin time (PT) < 14 sec; partial thromboplastin time (PTT) < 35 sec
Prothrombin time (PT), partial thromboplastin time (PTT) =< 1.5 x ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) < 50% of deviation from institutional upper limit of normal (IULN)
Normal prothrombin time (PT) for age
Prothrombin time (PT) no greater than 6 seconds longer than control.
Prothrombin time (PT) < 1.3 x upper limit of normal (ULN)
Prothrombin time (PT) with normal limits (WNL); if patient is on warfarin for prophylactic clot presentation for indwelling catheter, PT/partial thromboplastin time (PTT) may be +/- 15 %
Evidence of bleeding diathesis or coagulopathy as documented by an elevated prothrombin time (PT), partial thromboplastin time (PTT) or bleeding time
Prothrombin time (PT)/partial thromboplastin time (PTT) within normal limits (secpatient may be eligible for trial if abnormality is deemed clinically insignificant and cleared for protocol therapy by Hematology Consult service)
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.4 times upper limit of normal range
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 2 x normal outside the setting of stable chronic anticoagulation therapy
Prothrombin time less than 1.5 × ULN for the institution
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x upper limit of normal (ULN) unless receiving clinically indicated anticoagulant therapy
ORAL CAVITY SQUAMOUS CELL CARCINOMA COHORT: Prothrombin time (PT) and partial thromboplastin time (PTT) < 1.4 x ULN
HPV-ASSOCIATED OROPHARYNX SQUAMOUS CELL CARCINOMA: Prothrombin time (PT) and partial thromboplastin time (PTT) < 1.4 x ULN
Prothrombin time (PT) and/or partial thromboplastin time (PTT) =< 1.5 X ULN.
Prothrombin time/partial thromboplastin time (PT/PTT) ? 1.5 x upper limit of normal (ULN) (unless receiving anticoagulation)
Prothrombin time (PT) =< 1.5 x ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) ? 1.5 x of institutional upper limit of normal (ULN) (Note: If coagulopathy is related to disease, this criteria do not apply) within 14 days prior to registration
Prothrombin time (PT)/partial thromboplastin time (PTT) < 1.5 x normal institutional standard
Prothrombin Time (PT) and activated partial thromboplastin time (PTT) ? 1.6x unless therapeutically warranted
Prothrombin time (PT)/partial thromboplastin time (PTT) within normal limits (11.6 - 15.2 / 25.3 - 37.3 sec)
Prothrombin time (PT) > 12 seconds or partial thromboplastin time (PTT) > 31 seconds
Prothrombin time (PT) within 2 seconds of the upper limit of normal (ULN)
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 2 x ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x upper limit of normal (ULN)
Prothrombin time (PT) =< 1.2 x ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) within 1.5 times the institutional upper limit of normal
Normal coagulation [prothrombin time and partial thromboplastin time within normal limits (±15%)].
Prothrombin time (PT) or partial thromboplastin time (PTT) test >= 1.3 x laboratory upper limit of normal (ULN) within 7 days before the first dose of study treatment
Prothrombin time (PT) and partial thromboplastin time (PTT) ? 1.5 X ULN after correction of nutritional deficiencies that may have contributed to prolonged PT/PTT.
AMKL PATIENTS: Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x ULN
Coagulation: Prothrombin time (PT) <1.5 × ULN and partial thromboplastin time (PTT) <1.5 × ULN
Acceptable coagulation studies as demonstrated by prothrombin time (PT) and partial thromboplastin time (PTT) within normal limits (+/-15%).
Prothrombin time (PT) and partial thromboplastin time (PTT) < 1.4x the ULN
Prothrombin time (PT) and partial thromboplastin time (PTT) > 50% of deviation of institutional upper limit of normal (ULN)
Prothrombin time (PT) =< 1.5 times the upper limit of normal
Prothrombin time (PT) within normal limits (UIHC)
Adequate coagulation defined as:\r\n* Prothrombin time (PT) =< 1.2 x upper limit of normal
Prothrombin time (PT) < 1.2 x ULN
Patients must NOT have a prolonged prothrombin time (PT) or partial thromboplastin time (PTT) (greater than 1.2 times the institutional upper limit of normal)
Prothrombin time (PT) and partial thromboplastin time (PTT) > 50% of deviation of institutional ULN
Other: Prothrombin time (PT) and partial thromboplastin time (PTT) < ULN.
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 2 x ULN
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x upper limit of normal (ULN)
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x upper limit of normal (ULN)
Normal prothrombin time (PT)/partial thromboplastin time (PTT)
prothrombin time (PT) and activated partial thromboplastin time (PTT) ? 1.6 x control unless therapeutically warranted
Prothrombin time (PT) and partial thromboplastin time (PTT) must not be more than 1.5 x upper limit of normal (ULN) within 72 hours prior to enrollment; PT and PTT should be drawn by venipuncture, rather than from a central venous catheter when feasible
Prothrombin time (PT) and partial thromboplastin time (PTT) < 2 x normal outside the setting of stable chronic anticoagulation therapy
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 x institutional upper limits of normal
Prothrombin time (PT) and partial thromboplastin time =< 1.5 upper limit of normal (ULN) unless using warfarin for therapeutic anti-coagulation
Subjects must have normal coagulation parameters as measured by prothrombin time (PT)/partial thromboplastin time (PTT)
Prothrombin time (PT)/INR and partial thromboplastin time (PTT) =< grade 1 within two weeks before initial biopsy of visceral organs
Prothrombin time (PT) =< 2 x normal outside the setting of stable chronic anticoagulation therapy
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.2 X upper limit normal (ULN)
Prothrombin time (PT) and partial thromboplastin time (PTT) < 2 x normal outside the setting of stable chronic anticoagulation therapy
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 120% of control, unless patient has the presence of a lupus anticoagulant
Prothrombin time (PT), partial thromboplastin time (PTT) less than or equal to 1 to 1.5 x upper limit of normal, CTCAE v 4.0 grade 1 except for patients on therapeutic anticoagulation
Prothrombin time (PT)/partial thromboplastin time (PTT) =< 1.5 X ULN
Prothrombin time < 1.5 x ULN
Normal prothrombin time
Prothrombin time (PT) ? 1.5 x ULN
TREATMENT: Prothrombin time (PT) within 2 seconds of the upper limit of normal (ULN)
Coagulation status: prothrombin time (PT) ? 1.5 ULN or INR within normal limits; and partial thromboplastin time (PTT) ? 1.2 × ULN
No evidence of coagulopathy as indicated by prothrombin time (PT) =< 1.5 X upper limit of normal
Patients with known bleeding diathesis or prothrombin time (PT) or aPTT >1.5 x ULN or fibrinogen <0.5 x LLN
PART I: Absolute neutrophil count (ANC), hemoglobin, platelet, total bilirubin, creatinine, transaminase (aspartate aminotransferase [AST]/alanine aminotransferase [ALT]), prothrombin time (PT), partial thromboplastin time (PTT), urine uric acid, urine pH, urine oxalate must be within standard normal ranges
Prothrombin time (PT)/partial thromboplastin time (PTT) < 1.5 x upper limit of normal (ULN)
Prothrombin time (PT) or partial thromboplastin time (PTT) < 1.5 x institutional upper limit of normal (IULN)
Prothrombin time (PT) =< 4 seconds above upper limit of normal (ULN) and partial thromboplastin time (PTT) =< 10 seconds above ULN
Prothrombin time (PT)/partial thromboplastin time (PTT) within normal limits (WNL) of the institution
Prothrombin time (PT) or partial thromboplastin time (PTT) > 1.5 x the upper limit of normal, except if the patient is on therapeutic anticoagulation, in which case they should demonstrate stability of PT/PTT for at least two weeks
Prothrombin time (PT) < 1.5 ULN
Prothrombin time (PT) =< 1.5 times upper limit of laboratory normal (ULN)
Prothrombin time (PT) no more than 2 seconds above the upper limit of normal (ULN)
Prothrombin time (PT) =< 1.5 times upper limit of laboratory normal (ULN)
Prothrombin time > 1.5 x control
Have a bleeding disorder as determined by prothrombin time (PT) > 14.5 seconds, partial thromboplastin time (PTT) > 34 seconds, and platelet count < 140,000 platelets per microliter of circulating blood1
Prothrombin time (PT) and partial thromboplastin time (PTT) > 1.5 x ULN
Prothrombin time (PT) and partial thromboplastin (PTT) =< 1.5 x IULN
Prothrombin time greater than 50% of control
Prothrombin time (PT) and partial thromboplastin time (PTT) =< 1.5 x institutional upper limit of normal
Prothrombin time (PT)/partial thromboplastin time (PTT) within normal institutional limits
Presence of coagulopathy (prothrombin time [PT] or partial thromboplastin time [PTT] > 1.2 x upper limit of normal)
Thrombin time (TT), prothrombin time (PT), or partial thromboplastin time (PTT) > 2 x upper limit of normal
Patients not taking warfarin must have prothrombin time (PT)/partial thromboplastin time (PTT) levels =< 1.5 times the upper limit of normal provided by the reference laboratory performing the test
Prothrombin time (PT)/partial thromboplastin time (PTT) within normal institutional limits
PT/PTT/INR (prothrombin time/partial thromboplastin time) without clinically significant abnormalities after review by the study physicians
Contraindication to biopsy:\r\n* Bleeding disorders\r\n* Prothrombin time (PT)/partial thromboplastin time (PTT) >= 1.5 times the upper limit of normal\r\n* Artificial heart valve
Patients with coagulopathies who are at increased risk for bleeding or on active anti-coagulation therapy (platelets less than 100,000 per mm^3 or prothrombin time [PT]/partial thromboplastin time [PTT] greater than 1.5 times the upper normal limit [UNL]); patients are eligible if the underlying cause is correctable
Prothrombin time (PT)/partial thromboplastin time (PTT) =< the institution ULN
Prothrombin time > 1.5 x control
Coagulopathy (prothrombin time [PT] or partial thromboplastin time [PTT] > 1.5 x upper limit of normal)
Prothrombin time (PT), partial thromboplastin time (PTT) =< 1.5 times upper limit of normal