No history of grade 4 hypertension, defined as hypertension resulting in life-threatening consequences (e.g., malignant hypertension, transient or permanent neurologic deficit, hypertensive crisis) Uncontrolled hypertension Patients with uncontrolled hypertension (>= 140/90 mmHg) are NOT eligible for participation Uncontrolled hypertension Patients with uncontrolled hypertension; patients with a history of hypertension must be well controlled (< 160/90) on a regimen of hypertensive medication History of significant cardiac disease or uncontrolled hypertension Patients with uncontrolled hypertension (> 140/90 mmHg) are NOT eligible for participation Uncontrolled severe hypertension, according to the judgment of the investigator, or symptomatic hypertension Uncontrolled hypertension Uncontrolled hypertension Uncontrolled hypertension Uncontrolled hypertension Has uncontrolled or poorly controlled hypertension Uncontrolled hypertension Uncontrolled hypertension (> 150/100 mmHg) Hypertension that is not controlled by standard medication (to 150/90 mmHg or below), Uncontrolled hypertension, i.e., blood pressure (BP) of >= 160/95; patients who have a history of hypertension controlled by medication must be on a stable dose (for at least one month) and meet all other inclusion criteria; or Patients must not have uncontrolled hypertension Uncontrolled hypertension (HTN) Uncontrolled hypertension Patients with uncontrolled hypertension Hypertension that is unstable or not controlled by medication. Uncontrolled hypertension Patients with uncontrolled hypertension Patients with uncontrolled hypertension (HTN) (> 160/90) will not be admitted onto the study Criteria for hypertension: Blood pressure greater than 170/90 or 2 standard deviations (SD) from normal based on age and weight nomogram on 3 separate measurements; uncontrolled hypertension (HTN) Patients must not have symptomatic hypertension Severe or unstable cardiovascular disease or uncontrolled hypertension Uncontrolled hypertension Uncontrolled or severe hypertension, or cerebrovascular disease. Patients with diagnosed uncontrolled hypertension (> 150/90 mmHg) are to be excluded Patients with hypertension controlled with medications are allowed Uncontrolled hypertension (refer to World Health Organization [WHO]-International Society of Hypertension [ISH] guidelines) Uncontrolled hypertension, i.e., blood pressure (BP) of >= 160/95; patients who have a history of hypertension controlled by medication must be on a stable dose and meet all other inclusion criteria; or Uncontrolled hypertension defined as > 140/90 and not cleared for surgery at the time of consent Uncontrolled hypertension Have uncontrolled severe hypertension Uncontrolled hypertension DONOR: Current uncontrolled hypertension Uncontrolled hypertension Have a known history of uncontrolled hypertension. Patients with hypertension should be under treatment on study entry to control blood pressure. Patients with >= grade 2 uncontrolled hypertension Uncontrolled hypertension during screening Current uncontrolled hypertension Part 2: tachycardia and/or uncontrolled hypertension Uncontrolled hypertension at study entry; patients with a history of uncontrolled hypertension are allowed provided blood pressure is controlled by antihypertensive treatment Uncontrolled hypertension Uncontrolled hypertension Hypertension that is not controlled by standard medication (to 150/90 mmHg or below) Uncontrolled hypertension (> 150/90 mmHg) Hypertension not adequately controlled by 3 or less medications Hypertension not adequately controlled by 3 or less medications Uncontrolled hypertension defined as > 140/90 and not cleared for surgery at the time of consent Uncontrolled hypertension Uncontrolled hypertension. Poorly controlled hypertension Patients must not have a diagnosis of uncontrolled seizure or uncontrolled hypertension Have uncontrolled hypertension. uncontrolled cardiovascular disease or uncontrolled hypertension have uncontrolled hypertension Hypertension defined below: Uncontrolled hypertension Uncontrolled or poorly controlled hypertension. Severe or uncontrolled systemic diseases including uncontrolled hypertension Uncontrolled hypertension. Resisted hypertension Uncontrolled hypertension, i.e., blood pressure (BP) of >= 170/95; patients who have a history of hypertension controlled by medication must be on a stable dose (for at least one month) and meet all other inclusion criteria Controlled hypertension Current uncontrolled hypertension Uncontrolled hypertension Inadequately controlled arterial hypertension Uncontrolled hypertension History or evidence of poorly controlled hypertension Patients with uncontrolled hypertension (>= 145/90 mmHg) are NOT eligible for participation Poorly controlled hypertension Other clinically significant heart disease (e.g. uncontrolled hypertension, or history of labile hypertension) Hypertension Patients with poorly controlled hypertension Subject has uncontrolled hypertension. Uncontrolled hypertension defined as systolic greater than 180 and diastolic greater than 100 Uncontrolled hypertension Uncontrolled hypertension Inadequately controlled hypertension Uncontrolled hypertension Hypertension uncontrolled by medication Uncontrolled hypertension Known history of malignant hypertension (severe hypertension >180/120 mmHg with end organ involvement. Uncontrolled hypertension, i.e., blood pressure (BP) of >= 160/95; patients who have a history of hypertension controlled by medication must be on a stable dose (for at least one month) and meet all other inclusion criteria Uncontrolled hypertension (per the Investigator's discretion) Uncontrolled concurrent medical illness including uncontrolled hypertension Uncontrolled hypertension Uncontrolled hypertension (per Investigator's discretion) Uncontrolled hypertension Poorly-controlled hypertension Have >= Grade 2 uncontrolled hypertension Uncontrolled hypertension or chronic renal disease Uncontrolled hypertension; Hypertension other than mild essential hypertension controlled with medication Patients with uncontrolled hypertension. Uncontrolled hypertension. Have tachycardia and/or uncontrolled hypertension Uncontrolled hypertension, i.e., blood pressure (BP) of >= 160/95; patients who have a history of hypertension controlled by medication must be on a stable dose (for at least one month) and meet all other inclusion criteria; or Has untreated hypertension or has hypertension under treatment that meets protocol definitions. uncontrolled hypertension Patient has uncontrolled hypertension History of Uncontrolled hypertension Well-controlled hypertension Uncontrolled hypertension Uncontrolled hypertension. Clinically uncontrolled hypertension in the investigator's opinion (e.g., blood pressure >160/100 mmHg; note that isolated elevated readings considered to not be indicative of uncontrolled hypertension are allowed). The following within 6 months prior to Cycle 1 Day 1: