Adequate hematological, renal, metabolic and hepatic function within 7-10 days prior to randomization Adequate organ function as demonstrated by hematological, renal, hepatic laboratory assessments; Adequate cardiovascular, hematological, liver and renal function Adequate cardiac, hematological, liver and renal function Demonstrate adequate hematological, renal, hepatic, and coagulation function; Adequate hematological, hepatic and renal function prior to first dose Adequate hematological, hepatic and renal function Adequate hematological, renal, hepatic and coagulation function is required. Adequate hematological, hepatic, and renal function: Adequate hematological, renal, and liver function Adequate hematological, liver, and renal function Adequate hematological, hepatic and renal function (renal function considered adequate as per protocol definition) Adequate hematological, renal, hepatic, and coagulation laboratory assessments Abnormal hematological, renal, or liver function Adequate hematological, hepatic and renal function as defined in the protocol Adequate hematological, renal, metabolic and hepatic function Adequate hematological, renal, hepatic and coagulation laboratory test results. Other serious diseases (hematological, hepatic, renal, respiratory, central nervous system, autoimmune or psychiatric) Adequate hematological, hepatic and renal function as defined in the protocol Adequate hematological, renal and hepatic function Adequate hematological, renal, hepatic, and coagulation laboratory assessments Adequate hematological, liver, and renal function Adequate hematological, renal and liver function Adequate hematological, hepatic, and renal function: Adequate hematological, renal, hepatic, and coagulation laboratory assessments Adequate hematological, renal, hepatic and coagulation laboratory test results Adequate hematological, renal, and hepatic function Adequate hematological, renal, hepatic, and coagulation laboratory assessments Adequate hematological, renal and liver function For solid tumors only: Adequate hepatic, renal, cardiac and hematological function Adequate hematological, renal, metabolic and hepatic function Inadequate hematological, hepatic, or renal function Adequate hematological, renal, hepatic, and coagulation laboratory assessments Adequate hematological, renal and liver function Participants with adequate hematological, liver, and renal function Adequate hematological, renal and hepatic function. Adequate hematological, hepatic, renal and cardiac function Adequate hematological, renal, hepatic, and coagulation laboratory assessments Adequate organ functions (hematological, hepatic, renal function) Adequate hematological, renal, and hepatic function