Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min within 30 days of day 1 of study
Serum creatinine ? 2.0 mg/dL or creatinine clearance ? 40 mL/min measured or calculated by Cockroft Gault equation.
Creatinine =< 1.5 mg/dl or creatinine clearance >= 60 cc/min (can be calculated by 24 hour urine or by the Cockroft-Gault formula)
Creatinine =< 2.0 mg/dL OR creatinine clearance (calculated clearance permitted) >= 40 mL/min by Cockcroft-Gault formula
Serum creatinine =< 1.5 mg/dL; if serum creatinine is > 1.5 mg/dL, calculate creatinine clearance using standard Cockcroft-Gault formula; creatinine clearance must be >= 50 mL/min to be eligible
Serum creatinine =< 2.0 mg/dL or calculated creatinine clearance >= 50 mL/min as determined by the Cockcroft-Gault equation
Obtained =< 21 days prior to registration: Creatinine =< 1.5 mg/dl OR creatinine > 1.5 mg/dl, estimated creatinine clearance must be >= 55 mL/minute by Cockcroft Gault formula
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min (calculated by Cockcroft Gault equation)
Creatinine ?1.2 mg/dL or clearance ?50ml/min (Cockcroft-Gault)
Calculated creatinine clearance (by Cockroft-Gault) >= 50 mL/min or serum creatinine below 2 g/dL
Creatinine ?1.5 mg/dL or calculated creatinine clearance using the Cockcroft-Gault formula ?60 mL/min or measured creatinine clearance
Serum creatinine =< 1.5 mg/dL or calculated creatinine clearance >= 40 mL/min as determined by the Cockcroft-Gault equation
Serum creatinine < 1.5 mg/dL or calculated creatinine clearance >= 50 mL/min within 30 days prior to registration estimated by the Cockcroft-Gault formula
Serum creatinine calculated creatinine clearance by the method of Cockcroft and Gault (< 50mL/min)
Patients must have a serum creatinine of less than or equal to 1.3 mg/dL or creatinine clearance > 70 ml/min as calculated by the Cockcroft-Gault formula
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 2 mg/dL, or calculated creatinine clearance > 50 mL/min (per the Cockcroft-Gault formula)
Creatinine =< 1.5 mg/dl or creatinine clearance >= 60 mL/min/1.73 m^2 (calculated per Cockcroft & Gault formula) for subjects with creatinine levels above institutional normal
Serum creatinine =< 2.0 mg/dL OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above 2 mg/dL (unless dysfunction is secondary to lymphoma involvement); creatinine clearance (Cr Cl) will be calculated with the use of the 24-hour creatinine clearance or modified Cockcroft-Gault equation
Either serum creatinine > 1.7 mg/dL, or creatinine clearance < 50 mL/min calculated by the Cockcroft Gault method, eventually confirmed by measured creatinine clearance (or measured glomerular filtration rate [GFR] using plasma clearance methods)
Serum creatinine =< 1.5 mg/dL, or calculated (using the formula of Cockcroft and Gault) or measured creatinine clearance >= 30 mL/min
Serum creatinine =< 1.5 mg/dL and /or calculated creatinine clearance (using Cockcroft-Gault formula) >= 30 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Creatinine =< 1.5 mg/dL or creatinine clearance >= 40 mL/min using Cockcroft-Gault formula, within 14 days of study registration (within 30 days for pulmonary and cardiac assessments)
Serum creatinine < 1.5 mg/dl within 7 days prior to starting the study drug or creatinine clearance rate (CCr) ? 50 mL/min within 7 days prior to starting the study drug determined by 24-hour collection or estimated by Cockcroft-Gault formula: CCr male = [(140 - age) x (wt in kg)]/[(Serum Cr mg/dl) x (72)] CCr female = 0.85 x (CrCl male)
Creatinine =< 2.0 mg/dL OR calculated creatinine clearance >= 50 mL/min (as calculated by the Cockcroft-Gault method)
Creatinine < 1.5 mg/dL OR creatinine clearance (by Cockcroft Gault formula) >= 50 mL/min
Serum creatinine =< 1.5 x mg/dL and/or calculated creatinine clearance (using Cockcroft-Gault formula) >= 30 mL/min
Serum creatinine less than or equal to 1.3 mg/dL; if creatinine is > 1 mg/dL the creatinine clearance should be > 40 mL/min as calculated using the Cockcroft-Gault formula
Creatinine =< 1.5 mg/dL × ULN, or calculated creatinine clearance (determined as per Cockcroft-Gault)
Creatinine < 1.5 mg/dl and/or creatinine clearance > 60 mL/min using the Cockcroft-Gault formula
CERITINIB INCLUSION CRITERIA: Creatinine OR creatinine clearance < 1.5 mg/dL >= 30 mL/min (calculated by Cockgraft-Gault) for patients with creatinine levels above ULN
Serum creatinine =< 1.5 mg/dL and/or calculated creatinine clearance >= 50 mL/min (via Cockroft and Gault)
Adequate renal function, estimated or calculated creatinine clearance of > 50 mL/min (calculated using the formula of Cockcroft and Gault) -or- serum creatinine ? 2.0 mg/dL.
Serum creatinine < 1.5 mg/dL and/or calculated creatinine clearance (using Cockcroft-Gault formula) >= 30 mL/min
Serum creatinine =< 1.5 mg/dL (=< 133 umol/L) OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Adequate renal function as defined by one of the following: \r\n• Serum Creatinine ?1.5 mg/dl OR \r\n• Serum Creatinine clearance > 50ml/min (calculated by Cockcroft-Gault formula)
Creatinine =< 1.5 mg/dL or creatinine clearance by Cockcroft-Gault formula >= 60 mL/min
Calculated creatinine clearance (by Cockroft-Gault) >= 50 ml/min or serum creatinine below 2 g/dL
Serum creatinine =< 1.5 mg/dL, or if serum creatinine is > 1.5 mg/dL, creatinine clearance must be >= 50 mL/min (calculate creatinine clearance using the Cockcroft-Gault formula
Creatinine =< 1.5 mg/dl OR creatinine clearance >= 55 mL/min using the Cockcroft-Gault equation for patients with creatinine levels above 1.5 mg/dl
Serum creatinine < 1.5 mg/dL and/or calculated creatinine clearance (using Cockcroft-Gault formula) >= 30 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 60 mL/min OR 24-hour urine creatinine clearance >= 60 mL/min
Serum creatinine level to be < 2 mg/dl or estimated creatinine clearance (CrCl) must be equal or greater than 40 mL/min/1.73 m^2 as calculated by the Cockcroft-Gault formula
Creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine of =< 1.5 mg/dL; if creatinine > 1.5 mg/dL creatinine clearance must be > 60 mL/min within 7 days prior to treatment either measured or calculated using a standard Cockcroft and Gault formula
Serum creatinine =< 1.6 mg/dL and creatinine clearance >= 30 ml/min; creatinine clearance will be calculated using the Cockcroft-Gault equation
Serum creatinine > 2.0 mg/dL or 177 ?mol/L or creatinine clearance < 40 mL/min (using the Cockcroft-Gault formula)
Creatinine =< 1.6 mg/dL; if over 1.6 then the calculated creatinine clearance must be >= 55 ml/min using the Cockcroft-Gault formula, obtained =< 7 days prior to registration
Serum creatinine =< 2 mg/dL. The Cockcroft-Gault formula will be used to calculate creatinine clearance in all subjects.
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min (calculated by Cockcroft Gault equation) =< 14 days prior to registration
Serum creatinine =< 2.0 mg/dL or creatinine clearance >= 40 mL/min (measured or calculated according to the method of Cockcroft and Gault), within 28 days of day 0.
Obtained =< 21 days prior to registration: Creatinine =< 1.0 mg/dL or creatinine clearance >= 45 ml/min using the Cockcroft-Gault formula
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine levels =< 1.5 mg/dl and calculated (by Cockcroft-Gault formula) or measured creatinine clearance >= 50 mL/min, obtained within 14 days prior to registration for protocol therapy
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min
Creatinine =< 2.0 mg/dL, OR calculated creatinine clearance >= 30 mL/min (calculated by the Cockcroft and Gault method)
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min (calculated by Cockcroft Gault equation)
Serum creatinine =< 1.5 mg/dL (=< 120 umol/L) OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockroft-Gault formula) >= 30 mL/min OR 24-hour urine creatinine clearance >= 30 mL/min
Blood creatinine =< 1.5 mg/dL (if blood creatinine is > 1.5 mg/dL, calculate creatinine clearance using standard Cockcroft and Gault method or using a 24 hour urine collection for creatinine; creatinine clearance must be > 50 mL/min), within 2 weeks of the first dose of study treatment
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min
Renal insufficiency at the time of screening, defined as serum creatinine > 2.0 mg/dL or creatinine clearance < 50 mL/min (either actual or calculated value may be used), within 7 days of initiation of protocol therapy; creatinine clearance will be the primary eligibility criteria in determining renal insufficiency; the Cockcroft-Gault formula should be used for calculating creatinine clearance values
Serum creatinine > 2.0 mg/dL or creatinine clearance < 40 mL/min measured or calculated by Cockroft-Gault equation.
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Creatinine less than or equal to 1.5 mg/dL or creatinine clearance greater than 40 mL/min/1.73 m2 for patients with creatinine levels above institutional normal, as calculated by the Cockcroft Gault formula.
Serum creatinine =< 2.0 g/dL or calculated creatinine clearance >= 60 mL/min (Cockcroft-Gault method)
Adequate renal function, with creatinine =< 1.3 mg/dl or calculated creatinine clearance >= 60 ml/min by Cockcroft and Gault equation using parameters of age, weight (kg), and baseline serum creatinine (mg/dl)
Any of the following laboratory abnormalities: Absolute neutrophil count(ANC) < 1,000/µL, Platelet count < 75,000/µL or < 50,000/µL for patients in whom ? 50% of bone marrow nucleated cells are plasma cells, Hemoglobin < 8 g/dL, Creatinine clearance < 45 mL/min according to Cockcroft-Gault formula. If creatinine clearance calculated from the 24 hour urine sample is ? 45 mL/min, patient will qualify for the trial, Aspartate transaminase (AST) or Alanine transaminase (ALT) > 3.0 × Upper Limited Normal (ULN), Serum total bilirubin > 2.0 mg/dL or > 3.0 × ULN for patients with hereditary benign hyperbilirubinaemia.
Creatinine: =< 1.5 mg/dL, OR calculated creatinine clearance >= 40 mL/min (calculated by the modified Cockcroft and Gault method)
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault method) >= 50 mL/minute within 14 days prior to treatment
Serum creatinine < 2.0 mg/dL or calculated creatinine clearance (CrCl) > 45 mL/min (Cockcroft-Gault)
Renal insufficiency (serum creatinine levels > 2.5 mg/dL, calculated creatinine clearance [Crcl] with Cockcroft-Gault formula, < 45 ml/min)
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 1.3 mg/dL; patients with serum creatinine > 1.3 mg/dL may be eligible if creatinine clearance (CrCl) >= 55 mL/min based on the standard Cockcroft and Gault formula
Creatinine =< 2.5 mg/dL OR calculated creatinine clearance >= 50 mL/min (as calculated by the Cockcroft-Gault method)
Serum creatinine < 1.5 mg/dL or calculated creatinine clearance >= 50 mL/min within 30 days prior to registration estimated by the Cockcroft-Gault formula
Creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 3.0 mg/dL or a calculated creatinine clearance of at least 15 mL/min (using the Cockcroft and Gault method)
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance > 45 mL/min; use either measured or calculated with Cockcroft-Gault formula
Creatinine =< 1.5 mg/dL or calculated creatinine clearance >= 40 mL/min per the Cockcroft and Gault formula
Creatinine < 2.0 mg/dl; renal function assessed by calculated creatinine clearance as follows: phase I subjects must have calculated creatinine clearance >= 60 ml/min by Cockcroft-Gault formula
Serum creatinine =< 2.5 mg/dL or a calculated creatinine clearance of at least 50 mL/min (using the Cockcroft and Gault method)
Adequate renal function as evidenced by serum creatinine less than 1.5 mg/dL or calculated creatinine clearance greater than 40 mL/min per the Cockcroft and Gault formula.
=< 10 days prior to enrollment/randomization: Creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min calculated by the Cockcroft-Gault method
Serum creatinine ? 1.5 mg/dL or a calculated creatinine clearance of ? 60 mL/min as determined by the Cockcroft-Gault equation
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 60 mL/min
Serum creatinine ? 1.5 mg/dL or calculated creatinine clearance (CrCl) of ? 60 mL/hour by the Cockroft-Gault equation;
Serum creatinine ? 1.5 mg/dL or creatinine clearance > 45 mL/min according to Cockcroft?Gault formula; (If creatinine clearance calculated from a 24-hour urine sample is ?45 mL/min, the subject will qualify for the study).
Creatinine =< 1.5 mg/dL to receive weekly intravenous cisplatin*; *patients whose serum creatinine is between 1.5 and 1.9 mg/dL are eligible for cisplatin if the estimated creatinine clearance is >= 30 ml/min; for the purpose of estimating the creatinine clearance, the formula of Cockcroft and Gault for females should be used
Serum creatinine < 1.5 mg/dL or calculated creatinine clearance >= 50 ml/min (by Cockcroft-Gault formula) within 14 days prior to registration
Adequate renal function as evidenced by serum creatinine less than or equal to (<=) 1.5 milligram per deciliter (mg/dL) or calculated creatinine clearance >=50 millimeter per minute (mL/min) according to the Cockcroft and Gault formula.
Creatinine ? 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) ? 50 mL/min OR 24-hour urine creatinine clearance ? 50 mL/min
Calculated creatinine clearance greater than 45 mg/dl using the Cockcroft-Gault formula
Creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Serum creatinine =< 2 mg/dL or a calculated creatinine clearance of >= 50 mL/min (using the Cockcroft and Gault method)
Clinical laboratory values should be as follows: WBC < 30,000/mL Blasts in PB ? 20,000. Treatment with Hydroxyurea is permitted up to 24 hrs prior to BL-8040 administration to achieve blast counts < 20,000 prior to enrollment. Creatinine < 1.3 mg/dL; if Creatinine is > 1 mg/dL the Creatinine clearance should be > 40 mL/min as calculated using the Cockcroft-Gault formula.
Creatinine =< 1.5 mg/dL or creatinine clearance >= 50 mL/min calculated by the Cockcroft-Gault method
Serum creatinine clearance >=50 ml/min (calculated with Cockroft-Gault formula); creatinine for children =<1.5 mg/dl or =< 2 times upper limit of normal for age (whichever is less)
Creatinine =< 1.5 mg/dL or creatinine clearance >= 40mL/mon (using Cockcroft-Gault formula)
Creatinine =< 1.5 mg/dL, or calculated creatinine clearance (determined as per Cockcroft-Gault) >= 50 mL/min
Creatinine =< 1.6 mg/dl (for patients with > 1.6 mg/dl, calculated or measured creatinine clearance must be >= 60 mL/minute [Cockcroft-Gault])
Serum creatinine ? 2.0 mg/dL or creatinine clearance ? 40 mL/min measured or calculated by Cockcroft-Gault equation.
Serum creatinine =< 1.5 mg/dL OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 mL/min OR 24-hour urine creatinine clearance >= 50 mL/min
Creatinine =< 1.5 mg/dl OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 ml/min OR 24-hour urine creatinine clearance >= 50 ml/min
Serum creatinine ?1.5 mg/dL, and creatinine clearance ? 50 ml/min as measured by Cockcroft and Gault formula
Serum creatinine ? 1.7 mg/dL or calculated creatinine clearance ? 50 mL/min per the Cockcroft and Gault formula