Symptomatic congestive heart failure (NYHA class ? II);
Patients with chronic kidney disease (glomerular filtration rate [GFR] < 60), uncontrolled hypertension, congestive heart failure, pre-existing bone marrow dysfunction, or cytopenias\r\n* Congestive heart failure (CHF): New York Heart Association (NYHA) class II-IV at the time of screening
Patients with any class of New York Heart Association (NYHA) congestive heart failure (CHF) or heart failure with preserved ejection fraction (HFPEF)
New York Heart Association (NYHA) Class II or higher congestive heart failure.
New York Heart Association heart failure class >= 3
Adequate cardiac function (?New York Heart Association [NYHA] Class II).
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions and/or ejection fraction < 40% by multigated acquisition (MUGA) scan or < 50% by echocardiogram and/or magnetic resonance imaging (MRI)
congestive heart failure > class II NYHA,
New York Heart Association (NYHA) functional class =< 2
Other clinically significant heart disease (New York Heart Association [NYHA] class 3 heart failure, uncontrolled hypertension)
Patients with a previous history of adriamycin treatment and are at risk of cardiac failure (New York Heart Association [NYHA] class II or above)
New York Heart Association (NYHA) cardiac class 3-4 heart disease
Congestive heart failure > New York Heart Association (NYHA) class 2
Congestive heart failure > New York Heart Association (NYHA) class 2
Symptomatic heart failure NYHA Class ? 3
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions and/or ejection fraction < 40% by MUGA scan or < 50% by echocardiogram and/or magnetic resonance imaging (MRI)
New York Heart Association (NYHA) class II or higher congestive heart failure
Congestive heart failure (CHF) NYHA Class ? 3, or
Documented New York Heart Association (NYHA) class I, II and III
Clinically evident congestive heart failure (CHF) > class II of the New York Heart Association (NYHA) guidelines (Appendix D).
New York Heart Association class 3-4 heart failure
New York Heart Association (NYHA) cardiac class 3-4 heart disease
Congestive heart failure New York Heart Association (NYHA) class 3 or 4
Patient with active heart disease (New York Heart Association [NYHA] class >= 3 as assessed by history and physical examination)
Congestive heart failure (CHF) NYHA (New York Heart Association) > Class 2
Heart failure > New York Heart Association (NYHA) class II
Clinically stable in New York heart association (NYHA) class 2 or 3 for the 3 months preceding screening Inclusion Criteria for Group 2
Subjects who were diagnosed with New York Heart Association (NYHA) Class II congestive heart failure or have clinically significant arrhythmia not controlled by medication prior to study entry.
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions
History or evidence of current >= class II congestive heart failure as defined by New York Heart Association (NYHA)
Documented New York Heart Association (NYHA) class I, II and III
Congestive heart failure > New York Heart Association (NYHA) class II
New York Heart Association (NYHA) class 3 or 4 congestive heart failure (CHF) symptoms
New York Heart Association (NYHA) congestive heart failure (CHF) class II or better
Congestive heart failure of any severity (New York Heart Association [NYHA] class I-IV)
New York Heart Association (NYHA) class II or higher congestive heart failure
Subject has congestive heart failure New York Heart Association (NYHA) class 3 or 4, or subject with a history of congestive heart failure NYHA class 3 or 4 in the past, unless a screening echocardiogram performed within 3 months prior to study entry results in a left ventricular ejection fraction that is ? 45%.
New York Heart Association (NYHA) class II or higher congestive heart failure
No New York Heart Association Class > II congestive heart failure
Current or history of congestive heart failure New York Heart Association (NYHA) class 3 or 4, or any history of documented diastolic or systolic dysfunction (LVEF < 50%, as measured by MUGA scan or echocardiogram)
NYHA ? Class 2.
Congestive heart failure - New York Heart Association (NYHA) > Class II.
Congestive heart failure greater than NYHA Class II
Unstable angina, significant cardiac arrhythmia, or New York Heart Association (NYHA) class 3 or 4 congestive heart failure
New York Heart Association (NYHA) congestive heart failure (CHF) class II or better
Patients with history of myocardial infarct within 6 months before enrollment, New York Heart Association (NYHA) class II or greater heart failure or symptoms suspicious for congestive heart failure are not eligible unless a Left ventricular ejection fraction (LVEF) in the past 6 months is documented to be 50% or greater; patients who have had a LVEF (performed for any reason) that is less than 50% in the past 6 months are ineligible
New York Heart Association (NYHA) Class II or higher congestive heart failure.
Congestive heart failure > New York Heart Association (NYHA) class 2
Any known unstable angina, significant cardiac arrhythmia, or New York Heart Association (NYHA) class 3 or 4 congestive heart failure
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions and/or ejection fraction < 45% by echocardiogram, or cardiac magnetic resonance imaging (MRI)
Congestive heart failure, defined as New York Heart Association (NYHA) Class II, within 3 months before C1D1 (see Appendix 1).
Congestive heart failure > class II New York Heart Association (NYHA) or unstable angina
New York Heart Association (NYHA) congestive heart failure (CHF) class II or better
Prior anthracycline treatment and at risk of cardiac failure (New York Heart Association Class 2)
Subject has congestive heart failure New York Heart Association (NYHA) class 3 or 4, or subject with a history of congestive heart failure NYHA class 3 or 4 in the past, unless a screening echocardiogram performed within 3 months prior to study entry results in a left ventricular ejection fraction that is ? 45%.
Active congestive heart failure (New York Heart Association [NYHA] class II-IV)
The following groups of patients are eligible provided they have New York Heart Association class II (NYHA) cardiac function on baseline echocardiogram (ECHO)/multi gated acquisition scan (MUGA):\r\n* Those with a history of class II heart failure who are asymptomatic on treatment\r\n* Those with prior anthracycline exposure\r\n* Those who have received central thoracic radiation that included the heart in the radiotherapy port
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) Class II to IV definitions and/or ejection fraction < 50% by multi-gated acquisition (MUGA) scan or by transthoracic echocardiogram
Major cardiac dysfunction, such as uncontrolled angina, congestive heart failure with New York Heart Association (NYHA) class III or higher, known left ventricular ejection fraction less than 40%
Subject currently has Class 3 or 4 New York Heart Association congestive heart failure.
Patients with any class of New York Heart Association (NYHA) CHF or heart failure with preserved ejection fraction (HFPEF)
Patients with New York Heart Association (NYHA) heart failure class > 2
-  Subject currently has Class 3 or 4 New York Heart Association congestive heart failure.
History of congestive heart failure New York Heart Association (NYHA) class 3 or 4 in the past, unless a screening echocardiogram or multi-gated acquisition scan performed within three months results in a left ventricular ejection fraction that is ? 45%;
Any of the following cardiac diseases currently or within the last 6 months as defined by New York Heart Association ([NYHA] Appendix G) ? Class 2
Patient with active heart disease (New York Heart Association [NYHA] class greater than or equal to 2 as assessed by history and physical examination)
Patients with New York Heart Association (NYHA) class 3 or 4 congestive heart failure
Class II-IV New York Heart Association (NYHA) congestive heart failure
congestive heart failure greater than New York Heart Association (NYHA) Class II according to the NYHA Functional Classification.
Subject has current symptomatic heart failure or a history of congestive heart failure New York Heart Association (NYHA) class 3 or 4
New York Heart Association (NYHA) congestive heart failure (CHF) class II or better
A history or evidence of current >=Class II congestive heart failure as defined by the New York Heart Association (NYHA) guidelines
Clinically evident congestive heart failure (CHF) > class II of the New York Heart Association (NYHA) guidelines.
Clinically evident congestive heart failure > class II of the NYHA guidelines.
Subject has congestive heart failure New York Heart Association (NYHA) class 3 or 4, or subject with a history of congestive heart failure NYHA class 3 or 4 in the past, unless a screening echocardiogram performed within 3 months prior to study entry results in a left ventricular ejection fraction that is ? 45%
Symptomatic heart failure – New York Heart Association (NYHA) class >= II symptoms
Congestive heart failure (CHF) that meets New York Heart Association (NYHA) class II to IV definitions and/or known ejection fraction < 40% by multi gated acquisition scan (MUGA) or < 50% by echocardiogram and/or magnetic resonance imaging (MRI)
History of cardiac disease including congestive heart failure > New York Heart Association (NYHA) Class II
Congestive heart failure of New York Heart Association (NYHA) class III or higher severity at study entry
A history or evidence of current >=Class II congestive heart failure as defined by the New York Heart Association (NYHA)
Patients with a history of congestive heart failure of any New York Heart Association class
Congestive heart failure New York Heart Association (NYHA) class 3 or 4, or subjects with history of congestive heart failure NYHA class 3 or 4 in the past, or history of anthracycline or anthracenedione (mitoxantrone) treatment, unless a screening echocardiogram or multi-gated acquisition scan (MUGA) performed within three months of the Screening visit results in a left ventricular ejection fraction that is ? 45%
The following groups of patients are eligible after consultation with a cardiologist and at the coordinating center PI’s discretion, provided they have New York Heart Association class II (NYHA) cardiac function on baseline echocardiogram (ECHO)/multigated acquisition scan (MUGA):\r\n* Those with a history of class II heart failure who are asymptomatic on treatment\r\n* Those with prior anthracycline exposure greater than a cumulative dose of 350 mg/m^2\r\n* Those who have received central thoracic radiation that included the heart in the radiotherapy port
Patients with New York Heart Association (NYHA) class II-IV heart failure
Cardiac failure, New York Heart Association (NYHA) Class II according to the NYHA Functional Classification,
Subject currently has Class 3 or 4 New York Heart Association congestive heart failure.
History of congestive heart failure (CHF) New York Heart Association (NYHA) class 3 or 4;
Uncontrolled heart failure as defined by New York Heart Association (NYHA) class 3 or 4
Clinically significant cardiac disease defined by congestive heart failure New York Heart Association (NYHA) Class 3 or Class 4.
History of New York Heart Association Class 3 or 4 heart failure;
Patients with class II heart failure or worse, per New York Heart Association (NYHA) classification
Congestive heart failure of New York Heart Association Class ? 3 or known left ventricular ejection fraction < 40%, or
Subject has uncontrolled angina, severe uncontrolled ventricular arrhythmias, electrocardiographic evidence of acute ischemia, congestive heart failure New York Heart Association (NYHA) class 3 or 4 or subject has a history of congestive heart failure NYHA class 3 or 4 in the past, unless a screening echocardiogram or multigated acquisition (MUGA) scan performed within 1 month prior to study entry results in a left ventricular ejection fraction that is ? 45%.
Confirmed left ventricular ejection fraction ?50% or any cardiac insufficiency > New York Heart Association (NYHA) class II currently or within the past 6 months,