Glomerular filtration rate (GFR) >= 35 mL/min estimated by Cockcroft-Gault or measured directly by 24 hour urine creatinine within 90 days prior to Step 1 registration
Serum creatinine (Scr) =< 1.5mg/dl; if the Scr > 1.5, patients may still be eligible if the calculated glomerular filtration rate (GFR) (Cockroft-Gault) is >= 40ml/minute
Serum creatinine ? 1.5 X ULN OR calculated glomerular filtration rate (GFR) by Cockcroft-Gault formula ? 50 mL/min
Renal function as follows: serum creatinine < 2.0 mg/dL (176.84 umol/L) and estimated glomerular filtration rate > 30 mL/min/1.73 m2.
Serum creatinine >1.5 x ULN and/or creatinine clearance or estimated glomerular filtration rate <30 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 50 mL/min
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine ? 1.5 mg/dL (or glomerular filtration rate ? 60 ml/min as determined by the Cockcroft-Gault equation)
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
if serum creatinine > 3mg/dL, estimated glomerular filtration rate (GFR) ? 20 mL/min
Serum creatinine =< 1.5 mg/dL OR calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine: < 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 75 cc/min; creatinine clearance (CrCl) by Cockcroft Gault will be used to estimate GFR
Creatinine =< 1.5 x IULN or glomerular filtration rate of >= 60 mL/min
Creatinine < 2.0 x ULN or estimated Glomerular Filtration Rate GFR [Cockcroft-Gault] > 30 mL/min
Pediatric population (patients < 18 years): creatinine within normal limits or calculated creatinine clearance >= 90 ml/min/1.73 m^2 as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR)
Serum creatinine < 2.0 ULN OR an estimated glomerular filtration rate ? 30 mL/minute using the Cockroft-Gault formula.
Creatinine clearance or glomerular filtration rate >= 70 ml/min/1.73 m^2 (calculated or measured as appropriate for age and level of concern by treating medical doctor [MD])
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x ULN
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
Creatinine < 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 50 ml/min by Cockcroft-Gault
A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR), per protocol-specified criteria.
Creatinine =< 1.6 mg/ml OR creatinine clearance (estimated glomerular filtration rate [eGFR]) >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal at the time DAC-THU and pembrolizumab treatment commences
Serum creatinine < 3.0 mg/dl or if elevated, a calculated glomerular filtration rate (GFR) of > 30 mL/min/1.73 m^2
Serum creatinine =< 1.5 mg/dL OR calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 2 mg/dL and estimated glomerular filtration rate or creatinine clearance >= 20 ml/min
Estimated creatinine clearance >= 30 mL/min (24 hour measured glomerular filtration rate [GFR] or modified Cockcroft Gault)
Creatinine ? 1.5 x upper limit of normal (ULN), or calculated glomerular filtration rate (GFR) > 40 mL/min (Cockcroft-Gault) if creatinine > 1.5x ULN
Serum creatinine level =< 1.5 mg/dL or estimated glomerular filtration rate >= 50 mL/min
Glomerular filtration rate (GFR) < 50 mL/min, as assessed using the standard methodology at the investigating center (i.e. Cockroft-Gault), or serum creatinine > 1.5 x ULN
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Serum creatinine =< 1.5 mg/dl or glomerular filtration rate > 50 ml/min
Creatinine =< 2.0 mg/dl (adults) and estimated glomerular filtration rate (GFR) >= 40 mL/min (pediatrics); adults with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have estimated glomerular filtration rate (GFR) > 40 mL/min
Within 3 months of registration: Glomerular filtration rate (GFR) >= 45 mL/min; Cockcroft-Gault formula will be used to calculate creatinine clearance
Serum creatinine within 0.5-1.4 mg/dL, or if serum creatinine outside 0.5-1.4 mg/dL, then renal function (creatinine clearance or glomerular filtration rate [GFR]) > 40 mL/min/1.73 m^2
Creatinine < 1.5 mg/dl or glomerular filtration rate > 50 ml/min
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60 mL/min)
Serum creatinine > 1.8 mg/dL OR glomerular filtration rate (GFR) < 30 mL/min
A serum creatinine based on age/gender, derived from the Schwartz formula for estimating glomerular filtration rate (GFR)
Within 14 days of first dose of study drug: Serum creatinine =< 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 45 mL/min using the Cockcroft Gault formula
Estimated creatinine clearance of >= 60 ml/min according to the Cockcroft-Gault formula, unless calculated to be < 60 ml/min or borderline in which case glomerular filtration rate (GFR) should be formally measured, e.g. with edetic acid (EDTA) scan
Patients should have serum creatinine < 1.5 x ULN and estimated glomerular filtration rate (GFR) of > 30 mL/min. If serum creatinine is >= 1.5 x ULN, then patient must have creatinine clearance >= 51 mL/min estimated using the Cockcroft-Gault equation.
Glomerular filtration rate ? 45 ml/min based on Cockcroft-Gault equation
Patients must not be suitable for concurrent cisplatin as determined by the following:\r\n* Creatinine clearance less than 60ml/min; glomerular filtration rate (GFR) should be assessed by calculation from serum/plasma creatinine (Cockcroft-Gault formula)\r\n* Common Terminology Criteria for Adverse Events (CTCAE) grade (Gr) >= 2 hearing loss\r\n* CTCAE Gr >= 2 neuropathy
Creatinine < 2.0 mg/dl for adults or glomerular filtration rate > 50 ml/min for children
Serum creatinine =< 1.5 x ULN or estimated glomerular filtration rate (GFR) >= 45 mL/min using Cockcroft Gault formula
Creatinine within institutional normal limits or Glomerular filtration rate (GFR) > 50 mL/min/m^2 (calculated by the Cockcroft-Gault equation), calculated as follows:\r\n* For males = ((140 – age[years]) x (body weight [kg]))/((72) x (serum creatinine [mg/dL]))\r\n* For females = 0.85 x male value
Creatinine within institutional normal limits or glomerular filtration rate (GFR) > 60 mL/min/m^2 (calculated by the Cockcroft-Gault equation)
Glomerular filtration rate (GFR) greater than or equal to 40 ml/min using the Cockcroft-Gault formula or serum creatinine less than or equal to 1.5 x upper limit of normal (ULN)
Creatinine clearance estimated glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2 (Cockcroft-Gault)
Within 14 days of registration: Serum creatinine =< 1.8 mg/dL; for patients with a creatinine > 1.5 mg/dL or a history of renal dysfunction, an estimated glomerular filtration rate >= 35 mL/min/1.73 m^2 is required
Creatinine: =< 3 mg/dl OR if serum creatinine > 3 mg/dl, estimated glomerular filtration rate (GFR) > 30 mL/min/1.73 m^2
Creatinine < 2 mg/dl; glomerular filtration rate (GFR) > 50 mL/min (Cockroft and Gault formula)
Serum creatinine =< 1.5 x ULN or 24-hour clearance >= 50 mL/min or calculated glomerular filtration rate (GFR) of 60cc/ml using the formula of Cockcroft and Gault
Serum creatinine =< 1.5 mg/dL or estimated glomerular filtration rate (GFR) (by Cockcroft-Gault) >= 50 mL/min or 12 or 24 hour urine creatinine clearance >= 50 mL/min, unless renal insufficiency is due to tumoral ureteral obstruction in which case eligibility will be determined by the national principal investigator (or national co-PI or MSKCC co-PI if the national PI is unavailable) with notification of the MSKCC Institutional Review Board (IRB)
Serum creatinine ?1.5×upper limit of normal (ULN), or glomerular filtration rate >25 mL/min, as calculated with the Cockcroft-Gault formula.
Creatinine clearance estimated (est.) glomerular filtration rate (GFR) >= 30 mL/min/1.73 m^2 (Cockcroft-Gault)
Serum creatinine =< 2 mg/dL (or glomerular filtration rate >= 40 ml/min)
Serum creatinine =< 1.2 mg/dL for subjects age 18 or >; if serum creatinine is > 1.2 mg/dL, nuclear glomerular filtration rate (GFR) will be measured; GFR will need to be >= 80 ml/min/1.73 m^2 for subjects =< 40 years old; children (age < 18): nuclear GFR >= 80 mL/min/1.73 m^2
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Creatinine < 2 mg/dl (or a glomerular filtration rate > 60)
Serum creatinine =< 2 mg/dL (or glomerular filtration rate >= 50 ml/min as determined by the Cockcroft-Gault equation)
OR if serum creatinine > 3 mg/dL, estimated glomerular filtration rate (GFR) ? 20 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) (or glomerular filtration rate [GFR] >= 60 ml/min for patients with creatinine > 1.5 x ULN)
Calculated creatinine clearance >= 60 mL/min (Cockcroft-Gault formula) or serum creatinine (Cr) less than institution ULN (the elderly will often have < 60 glomerular filtration rate [GFR])
Glomerular filtration rate (GFR) > 40 mL/minute as calculated by the Cockcroft-Gault formula
Creatinine < 2.0 x ULN or creatinine clearance (estimated [est.] glomerular filtration rate [GFR] [Cockcroft-Gault]) >= 30 mL/min
Creatinine =< 1.5 times upper limit of normal (ULN*) OR corrected glomerular filtration rate >= 70 ml/min\r\n* NOTE: *of institutional norms
Participants must have a creatinine < 3 mg/dl and a glomerular filtration rate (GFR) > 30 mL/min/1.73m^2
Serum creatinine < 2.0 mg/dl or glomerular filtration rate (GFR) > 40 mL/min/1.73m^2; patients with a creatinine > 1.2 mg/dl or a history of renal dysfunction must have glomerular filtration rate (GFR) > 40 mL/min/1.73 m^2
Serum creatinine =< 1.5 x ULN or glomerular filtration rate (GFR) of 60 cc/ml using the formula of Cockcroft and Gault
Creatinine =< 1.5 times upper limit of normal (ULN) OR glomerular filtration rate >= 70 ml/min
Serum creatinine <2.0 x upper limit of normal (ULN) or estimated glomerular filtration rate of > 50 mL/min as calculated by the Cockcroft Gault Method
Creatinine clearance (Cockcroft-Gault) greater than or equal to 30 mL/min or estimated (est) glomerular filtration rate (GFR) greater than or equal to 30 mL/min/1.73 m^2
Calculated creatinine clearance (CRCL) ?40 mL/min. Glomerular Filtration Rate (GFR) is calculated based on Cockcroft-Gault method.
Calculated creatinine clearance > 50 ml/min/1.73m^2 as calculated by the Schwartz formula for estimated glomerular filtration rate
Serum creatinine ? 1.25 x ULN; or if serum creatinine > 1.25 ULN, then calculated (Cockcroft-Gault formula, glomerular filtration rate (GFR) ? 60 mL/min;
Creatinine clearance or glomerular filtration rate greater than or equal to 50 mL/min/1.73 m^2
Pediatric Population (age <18): Calculated creatinine clearance ? 90 ml/min/1.73m2 as calculated by the Schwartz formula for estimated glomerular filtration rate (GFR)
Adult Population (age >18): Serum creatinine <1.0 mg/dL; if serum creatinine >1.0 mg/dL, then the estimated glomerular filtration rate (GFR) must be >60 mL/min/1.73 m2
Creatinine of =< 2 mg/dl and a calculated glomerular filtration rate (GFR) of > 50 mL/min/1.73 m^2
Estimated (calculated) or measured glomerular filtration rate >= 45 mL/min (or 45 mL/min/1.73 m^2); creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within 28 days prior to registration
CROSSOVER (STEP 2) REGISTRATION: Estimated (calculated) or measured glomerular filtration rate >= 45 mL/min (or 45 mL/min/1.73 m^2) within 28 days prior to registration; creatinine (mg/dl) used in calculation (Cockroft-Gault) must be obtained within 28 days prior to registration
Glomerular filtration rate >= 50 mL/min (calculated according to the formula of Cockcroft and Gault)
Serum creatinine < 1.5 X institutional ULN mg/dL OR glomerular filtration rate (GFR) >= 50 mL/min
creatinine ? 1.5 x upper limit of normal (ULN), or calculated glomerular filtration rate (GFR) > 50 mL/min if creatinine > 1.5x ULN
Creatinine clearance or glomerular filtration rate of >= 70 ml/min/1.73m^2
Serum creatinine < 2.0 mg/dl (provided they also have a glomerular filtration rate of at least 55 ml/min)
Serum creatinine > 1.6 mg/dL or glomerular filtration rate < 50
Glomerular filtration rate > 60ml/min; OR =< ULN creatinine per institution normals
Serum creatinine =< 1.5 mg/dL or calculated glomerular filtration rate (GFR) >= 60 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) (or glomerular filtration rate >= 40 mL/min), obtained within 14 days of the first dose of study drug
Serum creatinine > 1.6 mg/dL (141 umol/L) in females and > 1.9 mg/dL (168 umol/L) in males; patients with serum creatinine values exceeding these limits are eligible for the study if their estimated glomerular filtration rates (GFR) are > 30 ml/min/1.73 m^2
Creatinine < 2.0 mg/dL, for patient with a creatinine > 1.2 mg/dL or a history of renal dysfunction an estimated glomerular filtration rate > 40 mL/min/1.73 m^2 is required
Creatinine =< 2.0 mg/dL, for patient with a creatinine > 1.2 mg/dL or a history of renal dysfunction an estimated glomerular filtration rate >= 40 mL/min/1.73 m^2 is required
Creatinine serum level >= 2 mg/dL or glomerular filtration rate (GFR) =< 30 mL/min/1.73 m^2 (contraindication for intravenous [i.v.] gadolinium only)
Creatinine > 1.8 mg/dL OR glomerular filtration rate (GFR) < 30 mL/min
Serum creatinine > 1.5 mg/dL or glomerular filtration rate < 50