Clinical signs or symptoms of gastrointestinal obstruction or requirement for routine parenteral hydration, parenteral nutrition, or tube feeding Clinical signs or symptoms of GI obstruction or requirement of routine parenteral nutrition or tube feedings Clinical signs or symptoms of gastrointestinal obstruction or requirement for routine parenteral hydration, parenteral nutrition, or tube feeding History of intestinal obstruction and/or clinical signs or symptoms of GI obstruction including sub-occlusive disease related to the underlying disease or requirement for routine parenteral hydration History of intestinal obstruction and/or clinical signs or symptoms of GI obstruction including sub-occlusive disease related to the underlying disease or a requirement for routine parenteral hydration, parenteral nutrition, or tube feeding within 6 months prior to Day 1 of Cycle 1 Clinical signs or symptoms of active GI obstruction or requirement of routine parenteral nutrition or tube feedings Requirement at baseline for parenteral or gastrointestinal tube-delivered nutrition for any reason Clinical signs or symptoms of GI obstruction or requirement for routine parenteral hydration, parenteral nutrition, or tube feeding Clinical signs or symptoms of GI obstruction or requirement of routine parenteral nutrition or tube feedings