Adequate renal, bone marrow, hepatic, pulmonary, and cardiac function Adequate bone marrow, renal, and liver function Has adequate bone marrow, renal and hepatic function based upon laboratory tests as follows: Participant has adequate bone marrow, renal, and hepatic function. Adequate bone-marrow, renal and liver function. Participants have adequate bone marrow, renal, hepatic and coagulation function. Adequate hepatic, renal, and bone marrow function: Adequate Bone Marrow, Renal, and Liver Function. Must have adequate bone marrow, liver, and renal function as described in protocol Patients must have adequate bone marrow, hepatic and renal function as defined below: Adequate bone marrow function, hepatic function, and renal function Participant has adequate bone marrow, renal and hepatic function. Severe bone marrow, renal or liver impairment. Adequate Bone Marrow, Liver, Renal, Pancreatic Function Adequate bone marrow, renal, hepatic, and metabolic function (assessed ? 7 days before inclusion in the study): Adequate bone marrow, liver, renal, and cardiac function at study entry, assessed as follows: Adequate bone marrow, renal and liver function Adequate bone marrow reserve, liver and renal function Adequate bone marrow, liver, and renal function. Adequate bone marrow, liver, and renal function Adequate bone marrow, renal, and liver function Adequate bone marrow, liver and renal function Adequate bone marrow, renal and liver function. Must have adequate bone marrow, renal, and hepatic function (For the sub-study, the subject must have adequate bone marrow and renal function and have mild-to-moderate hepatic impairment) Adequate bone marrow (BM), renal, hepatic and metabolic function. Adequate bone marrow reserve, cardiac, liver, renal and metabolic function: Adequate marrow, liver, and renal function: Patients must have adequate bone marrow, liver, coagulation and renal function within 7 days prior to study registration, as defined below: Adequate bone marrow, renal, hepatic, pulmonary, and cardiac function Participants have adequate bone marrow, renal, hepatic and coagulation function. Bone marrow, hepatic, and renal function as follows: Hepatic function, renal function, bone marrow function in defined lab-value-ranges Subject has adequate bone marrow, renal, and hepatic function. Adequate bone marrow, renal, hepatic, pulmonary, and cardiac function defined as: Adequate bone marrow reserves, hepatic function, and renal function Adequate bone marrow, liver, renal and coagulation function Must have adequate bone marrow and renal/hepatic function at the screening and baseline visits, defined as: Adequate bone marrow, renal and liver function. Adequate renal, liver and bone marrow function: Adequate bone marrow, hepatic, and renal function Adequate bone marrow, hepatic, and renal function, as specified in the protocol Participants must have adequate bone marrow, hepatic and renal function Adequate bone marrow, hepatic, and renal function, as specified in the protocol Adequate bone marrow (BM), renal, hepatic and metabolic function; Adequate bone marrow, renal and liver function. Participant has adequate bone marrow, renal, and hepatic function. Adequate bone marrow, liver and renal function. Adequate bone marrow, hepatic, and renal function Adequate bone marrow, renal and hepatic function: Patient has adequate bone marrow, coagulation, liver and renal function Adequate Bone Marrow, Pancreatic Function, Renal Function and Liver Function. Participant must have adequate bone marrow, renal, and hepatic function. Adequate renal, liver, and bone marrow function according to the following criteria: Adequate liver, bone marrow and renal function Subject has adequate bone marrow, renal, hepatic and coagulation function. Adequate bone marrow (BM), renal, hepatic, and metabolic function (assessed ? 14 days before inclusion in the study): Subjects must have adequate bone marrow, renal and hepatic function and coagulation Adequate hepatic, renal and bone marrow function. Adequate bone marrow, renal, liver and pancreatic function Participants must have adequate bone marrow, renal and hepatic function Adequate bone marrow, liver and renal function Adequate bone marrow, liver and renal function Adequate bone marrow, renal, and liver function. Acceptable bone marrow, renal, and hepatic function based upon screening lab tests Adequate bone marrow, liver and renal function renal function Subject must have adequate bone marrow, renal and hepatic function. Adequate bone marrow, hepatic, renal and cardiac function Adequate hepatic, renal, and bone marrow function Patients with adequate bone marrow, renal and hepatic function: Adequate bone marrow reserve, hepatic and renal function Adequate bone marrow, renal and liver function. Adequate bone marrow, liver and renal function Adequate bone marrow, renal, and hepatic function. Adequate bone marrow, liver and renal function Adequate renal, hepatic, and bone marrow function demonstrated by protocol-specified laboratory parameters at the screening visit. Adequate bone marrow, hepatic and renal function as evidenced by: Adequate bone marrow, renal, liver, cardiac and pulmonary function. Adequate bone marrow, liver and renal function Adequate bone marrow, renal capacity and hepatic function Adequate bone marrow, liver and renal function Adequate bone marrow, liver, and renal function Patients must have adequate bone marrow function (ANC >/= 1,500/mm3 and platelet count of >/= 100,000/mm3), adequate liver function (SGPT and serum glutamate oxaloacetate transaminase (SGOT)