No history of psychiatric disorders that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, substance abuse, severe personality disorder) or prevent the patient from giving informed consent
Presence of any serious or unstable concomitant systemic disorder incompatible with the clinical study (e.g., substance abuse, psychiatric disturbance, uncontrolled intercurrent illness including arterial thrombosis, or symptomatic pulmonary embolism)
Known significant mental illness or other condition, such as active alcohol or other substance abuse or addiction, that in the opinion of the investigator predisposes the subject to high risk of noncompliance with the protocol.
A history of substance abuse as defined by version IV of the Diagnostic & Statistical Manual of Mental Disorders (DSM IV).
SAFETY RUN-IN: Active substance abuse or psychiatric disorders
RANDOMIZED PHASE II CLINICAL TRIAL: Active substance abuse or psychiatric disorders
Participants with an unstable major psychiatric disorder, as assessed by study clinician, or a diagnosis of alcohol abuse (more than 5 drinks in a 24 hour period) or substance dependence within the past 1 year (as determined by a standard psychiatric interview) will be excluded unless otherwise approved by the PI or PI’s designee
Active substance abuse
Documented History of Alcoholism and or drug abuse
Known substance abuse or receiving concurrent treatment with non-permitted drugs.
Any concurrent uncontrolled illness, including mental illness or substance abuse, which in the opinion of the Investigator, would make the subject unable to cooperate or participate in the trial.
History of active ethanol abuse
Active, uncontrolled psychiatric disorders or substance (drug/alcohol) abuse that interfere with patient’s safety, ability to provide informed consent, or ability to comply with the protocol
Known to have recent history of drug abuse or alcoholism.
History of alcohol or other substance abuse within the last year.
Known significant mental illness or other conditions such as active alcohol or other substance abuse/addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol
Psychiatric illness, substance abuse
History suggestive of substance abuse
Patient has alcohol or substance abuse which, in the opinion of the investigator, would interfere with compliance or safety
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the MINI International Neuropsychiatric Interview (MINI): items C (current manic or hypomanic episode only), I (alcohol abuse - Alcohol Addendum - past 6 months only; current alcohol dependence), J (substance abuse - Substance Abuse Addendum - past 6 months only; current substance dependence), K (current psychotic disorder or current mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator and/or study physician
Testing positive on a urine drug screen for drugs of abuse/potential abuse
Patients with substance abuse or other medical or psychiatric conditions that, in the opinion of the investigator, would confound study interpretation or affect the patient's ability to tolerate or complete the study.
Known significant mental illness or other condition such as active alcohol or other substance abuse or addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol.
Known or suspected substance abuse or alcohol abuse
Known significant mental illness or other condition such as active alcohol or other substance abuse or addiction that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol.
Past or present history of active substance abuse (drug or alcohol)
Substance abuse or other concurrent medical or psychiatric conditions that, in the\n             Investigator's opinion, could confound study interpretation or affect the patient's\n             ability to tolerate or complete the study
History of active substance or alcohol abuse within the last year
History of active substance or alcohol abuse within the last year
Known significant mental illness or other conditions such as active alcohol or other substance abuse that, in the opinion of the investigator, predisposes the subject to high risk of noncompliance with the protocol treatment or assessments.
Psychiatric disorders and substance (drug/alcohol) abuse
History of alcohol or substance abuse
Any condition, psychiatric, substance abuse, or otherwise, that, in the opinion of the Investigator, would preclude informed consent, consistent follow-up, or compliance with any aspect of the study
Subject has addictive/substance abuse problems.
Use of any substance known to cause AME
DONOR: Active substance abuse
Subject has a documented history of substance abuse (narcotics, alcohol, etc.) or substance dependency in the 6 months prior to baseline data collection
Has known psychiatric or substance abuse disorders.
Have a history of alcohol of substance abuse, unless in full remission for greater than 6 months prior to the screening visit (day 0) when the consent form is signed
Active substance abuse
History of alcohol or substance abuse, unless in full remission for more than 6 months prior to start of study treatment
Donor must not have active alcohol or substance abuse within 6 months of study entry.
Recipient must have no active alcohol or substance abuse within 6 months of study entry.
Stable, good mental health (e.g., no recent unstable or untreated psychiatric diagnosis, including substance abuse, as determined by the DSM-IV criteria).
History of medical or psychiatric disease, active substance abuse or social circumstances which in the view of the principal investigator, would preclude safe treatment
Self-reported active alcohol or substance abuse within the last 30 days
History of substance abuse.
Have a current diagnosis of seasonal affective disorder or substance abuse
Are in treatment for substance abuse (e.g., illicit drugs, alcohol abuse)
History of substance abuse
History of substance abuse
Have a psychiatric diagnosis that would require significant study modification to meet their needs such as uncontrolled severe mental illness, substance abuse, or active suicidal ideation
Illicit substance abuse within the past 6 months
History of substance abuse
Active substance abuse at time of registration (alcohol, drugs, non-prescription use of controlled substances)
History of marked anxiety disorder, or history of substance abuse
Patients with history of alcohol or substance abuse by using Cut-down, Annoyed, Guilty, Eye-opener adapted to include Drug use questionnaire (CAGE-AID) score of 2 or higher
Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g., untreated major depression or psychosis, substance abuse, severe personality disorder)
Parents of ALL or AML survivors with a history of a major psychiatric condition that precludes participation (e.g., psychosis, severe depression, active substance abuse)
Parent/Caregiver: parents with a history of a major psychiatric condition that precludes participation (e.g., psychosis, severe depression, active substance abuse)
Child: survivors with a history of a major psychiatric condition that precludes participation (e.g., psychosis, severe depression, active substance abuse)
Breast cancer survivors (BCS) with other major disabling medical, psychiatric, or substance abuse conditions (e.g., anxiety, depression, alcohol/tobacco problems) will be excluded
Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, substance abuse, severe personality disorder)
History of opioid abuse
Ongoing or recent history of drug abuse.
Patients have a known history of seasonal affective disorder or substance abuse
Active alcohol or substance abuse issue
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the Mini International Neuropsychiatric Interview (MINI): items C (current manic or hypomanic episode only), I (alcohol abuse - alcohol addendum-past 6 months only; current alcohol dependence), J (substance abuse - substance abuse addendum - past 6 months only; current substance dependence), K (psychotic disorder or mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator
Psychiatric conditions, social situations or substance abuse that precludes the ability of the subject to cooperate with the requirements of the trial and protocol therapy
Meet criteria for the following psychiatric and/or substance use disorders as assessed by the Mini International Neuropsychiatric Interview (MINI); items C (current manic or hypomanic episode only), I (alcohol abuse-Alcohol Addendum-past 6 months only; current alcohol dependence), J (substance abuse-Substance Abuse Addendum-past 6 months only; current substance dependence), K (current/lifetime psychotic disorder or current/lifetime mood disorder with psychotic features); individuals who meet criteria for non-exclusionary psychiatric disorders that are considered clinically unstable and/or unsuitable to participate as determined by the principal investigator and/or study physician
Recent history (within 6 months) of alcoholism or drug abuse
Recent extended history of constant-recurrent substance abuse or another medical condition that might compromise safety or the successful completion of the study
Subjects with drug, alcohol, or substance abuse reported within the last three years (subject reported);
Have a history of alcohol or substance abuse, unless in full remission for greater than 6 months prior to the screening visit (day 0) when the consent form is signed
Psychiatric disorders or conditions that, in the opinion of the investigator, would preclude participation in the study intervention (e.g. untreated major depression or psychosis, substance abuse, severe personality disorder).
With current substance abuse and/or history of substance abuse, as per medical records or patient report
Individuals with known or suspected substance abuse, obtained by self-reporting.
History of substance abuse
History of alcoholism or other substance abuse
Substance abuse within the past 2 years
Any concurrent uncontrolled illness, including mental illness or substance abuse, which in the opinion of the Investigator, would make the subject unable to cooperate or participate in the trial.
Has a known psychiatric and/or substance abuse disorder that would make it difficult for the participant to cooperate with the requirements of the trial
Recent unstable or untreated psychiatric diagnosis including substance abuse, as determined by the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria