Uncontrolled hypercalcemia or symptomatic hypercalcemia requiring continued use of bisphosphonate therapy;
Uncontrolled tumor-related pain, or uncontrolled hypercalcemia or clinically significant (symptomatic) hypercalcemia
Serum calcium (corrected for albumin) level at or below the ULN range (treatment of hypercalcemia is allowed and subject may enroll if hypercalcemia returns to normal with standard treatment) prior to study therapy initiation
Serum calcium (corrected for albumin) level at or below the ULN (treatment of hypercalcemia is allowed and participant may enroll if hypercalcemia returns to normal with standard treatment).
History of hypercalcemia
Uncontrolled or symptomatic hypercalcemia
Uncontrolled disease-related metabolic disorder (e.g., hypercalcemia);
Uncontrolled hypercalcemia
Hypercalcemia
Uncontrolled hypercalcemia
History of either symptomatic hypercalcemia or hyperparathyroidism, at the treating investigator’s discretion
Hypercalcemia
Serum calcium (corrected for albumin) level above the ULN range (treatment of hypercalcemia is allowed and subject may enroll if hypercalcemia returns to normal with standard treatment).
Uncontrolled hypercalcemia
< Grade 3 hypo/hypercalcemia
Uncontrolled hypercalcemia
Uncontrolled hypercalcemia or symptomatic hypercalcemia requiring continued use of bisphosphonate therapy or denosumab
Uncontrolled or symptomatic hypercalcemia
Uncontrolled hypercalcemia or symptomatic hypercalcemia requiring continued use of bisphosphonate therapy or denosumab General Medical Exclusion Criteria:
Uncontrolled or symptomatic hypercalcemia
History of hypercalcemia
History of clinically significant hypercalcemia
Uncontrolled hypercalcemia
Uncontrolled hypercalcemia
Symptomatic hypercalcemia
The patient has hypercalcemia.
The patient has hypercalcemia.
Uncontrolled hypercalcemia
Uncontrolled hypercalcemia
Subjects with hypercalcemia (> 10.5 mg/dL)
Uncontrolled hypercalcemia or symptomatic hypercalcemia requiring continued use of bisphosphonate therapy
Subjects may be taking calcium supplements or have previous history of hypercalcemia
Known hypercalcemia
Uncontrolled or symptomatic hypercalcemia
Patients with hypercalcemia or kidney stones