Have an ECOG PS score of 0 or 1 STEP II: ECOG performance status 0, 1, or 2 (PS 3 allowed if secondary to pain) ECOG performance status (PS) score 0-1. ECOG PS 0-1. Patients must have an ECOG Performance Status (PS) ? 1. ECOG performance status (PS) ? 1. ECOG PS of 0-2 Have an ECOG performance status (PS) of ?2. ECOG performance status (PS) of 0 or 1 a. ECOG PS of 2 may be eligible upon the review and approval of the Medical Monitor. Subjects with PS of 0 or 1 on the ECOG Performance Scale Subject has a performance status (PS) of 0-2 according to the Eastern Cooperative Oncology Group (ECOG) scale. Subjects with ECOG PS of 3 may be included if decreased PS is secondary to DLBCL only, and not to comorbidities. ECOG PS >= 2 Patients must have an ECOG PS of 0-1 at screening. ECOG PS 0, 1, or 2. Performance Status (PS) ? 2: The patient has an ECOG PS of 0-2. PHASE IB: ECOG PS 0-1 Have an ECOG PS of 0 to 1, with the exception of patients in Part 2 (Cohort 3, unfit bladder cancer patients) who may have an ECOG PS of 2 ECOG PS score of 0 to 2 ECOG Performance Status (PS) 0-2; + 0 for (PS=0), +2 for (PS=1), +4 for (PS >1). ECOG PS >2. ECOG Performance Status (PS) 0-1; FULL STUDY INCLUSION CRITERIA: ECOG PS of 0 or 1 ECOG PS of 0 to 2 at screening. ECOG performance status (PS) 0-2 ECOG performance status (PS) of 0 or 1 Has an ECOG PS of 0, 1, or 2 ECOG PS 0-2. Subjects with high PB blasts >50% AND poor ECOG PS of 2. Patients must have an ECOG PS of 0-1 at screening and on the day prior to treatment. ECOG PS 0 or 1 ECOG PS 0-1. ECOG performance status (PS) ? 1 ECOG PS 0-2 Performance status (ECOG PS) 0-2 PS ECOG < 2 Performance status (PS) >70% Karnofsky or ECOG ?2; ECOG performance status (PS) 0 to 2. ECOG Performance Status (PS) 0-1; ECOG performance status (PS) 0-3 (restricted to ECOG PS 0-2 if >= 70 years of age) ARM B: ECOG performance status (PS) 0 or 1 Subjects must have ECOG PS of 0 to 2. ECOG PS 0-1 Patient must have ECOG PS of 0 to 2 ECOG PS 0 - 2 The patient has an ECOG performance score (PS) of 0-2. The patient has an ECOG performance score (PS) of 0-2. ECOG performance status (PS) of 0 or 1 ECOG Performance Status (PS) score of 0-1. PS 0 to 1 PS 2 ECOG-PS 0 or 1 ECOG PS of ?1. ECOG PS of 0 or 1. Patients with an ECOG PS of 2 may be entered upon review and approval of the medical monitor. ECOG PS of 0, 1, or 2 Subjects must have ECOG PS of 0 to 1. Eastern Cooperative Oncology Group performance status (ECOG PS) 0 to 2. In case of ECOG PS 2, the PS has to be due to metastatic prostate cancer to the bone. Zubrod performance status (PS) 0-2 or equivalent Karnofsky PS ECOG Performance Status (PS)