Obtained within 14 days prior to treatment start: Potassium (K) within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Obtained within 14 days prior to treatment start: Total calcium (CA) (corrected for serum albumin) within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Obtained within 14 days prior to treatment start: Magnesium within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Obtained within 14 days prior to treatment start: Sodium (NA) within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Obtained within 14 days prior to treatment start: Phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Potassium, total calcium (corrected for serum albumin), magnesium, and phosphorus within normal limits for the institution or corrected to within normal limits with supplements
Potassium, total calcium (corrected for serum albumin), magnesium, and sodium within normal limits for the institution or corrected to within normal limits before first dose of study medication
Potassium, sodium, calcium (corrected for serum albumin), magnesium, and phosphorus within normal limits for the institution;
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Patients must have the following laboratory values within the laboratory normal limits or corrected to within normal limits with supplements during screening:\r\n* Potassium\r\n* Magnesium\r\n* Phosphorus\r\n* Total calcium (corrected for serum albumin)
Total Ca (corrected for serum albumin) w/in normal limits
Serum sodium within normal limits or corrected to within normal limits with supplements before starting treatment
Potassium within normal limits or corrected to within normal limits with supplements before starting treatment
Magnesium within normal limits or corrected to within normal limits with supplements before starting treatment
Phosphorus within normal limits or corrected to within normal limits with supplements before starting treatment
Clotting parameters within normal limits or maximum 25% outside of the the normal ranges
serum troponin T levels within normal limits;
Patient must have the following laboratory values or have the following laboratory values corrected with supplements to be within normal limits before the first dose of ceritinib + trametinib:\r\n* Potassium\r\n* Magnesium\r\n* Phosphorus\r\n* Total calcium (corrected for serum albumin)
Potassium, total calcium (corrected for serum albumin), magnesium, and sodium within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Potassium, sodium, and total calcium (corrected only in the case of hypoalbuminemia) within normal limits of the local laboratory (screening values can be rechecked after electrolyte repletion and before the first dose of study medication, if necessary)
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Total calcium (corrected for serum albumin) within normal limits prior to the first dose of study medication
Potassium, sodium, calcium corrected for serum albumin and magnesium within normal limits or corrected to within normal limits with supplements before first dose of the study medication
Potassium, sodium, magnesium, and calcium (corrected for serum albumin) =< grade 1 or within the institutional ranges of normal; if clinically appropriate, electrolytes may be corrected and values reassessed prior to enrollment (within 14 days prior to registration)
Patients must have the following laboratory values or have the following laboratory values corrected to be within normal limits before the first dose of ceritinib:\r\n* Potassium\r\n* Magnesium\r\n* Phosphorus\r\n* Total calcium (corrected for serum albumin)
Serum sodium, potassium, magnesium and calcium within normal limits for the institution (supplements may be given to correct values)
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
CAPMATINIB INCLUSION CRITERIA: Serum potassium, calcium (corrected for serum albumin), magnesium, phosphorus within normal limits with or without supplementation
CERITINIB INCLUSION CRITERIA: Serum potassium, calcium (corrected for serum albumin), magnesium, phosphorus within normal limits with or without supplementation
REGORAFENIB INCLUSION CRITERIA: Serum potassium, calcium (corrected for serum albumin), magnesium, phosphorus within normal limits with or without supplementation
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed)
Newly diagnosed MCL: Uric acid within normal limits (allopurinol is allowed to bring abnormal level to within normal limits)
Prothrombin time (PT) within normal limits or planned and feasible to be corrected to normal limits prior to vertebroplasty
Partial thromboplastin time (PTT) within normal limits or planned and feasible to be corrected to normal limits prior to vertebroplasty
Potassium, Magnesium, Phosphorus, total Calcium (corrected for serum albumin) outside of normal limits (patients may be enrolled if corrected to within normal limits with supplements during screening)
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed)
9. Adequate organ function as defined by the following: \r\na. Serum creatinine =< 2 x the upper limit of normal (ULN), or glomerular filtration rate > 20 ml/hour (h) as calculated by Cockcroft-Gault formula.\r\nb. Serum potassium, magnesium, and calcium (corrected for albumin) within institutional normal limits or can be corrected with supplementation.\r\nc. Total serum bilirubin =< 2.5 x ULN.\r\nd. Serum aspartate transaminase (AST) and/or alanine transaminase (ALT) =< 2.5 x ULN.
Albumin within normal limits
Potassium within normal limits for the institution, or corrected with supplements
Calcium (corrected for albumin) within normal limits (oral supplementation is allowed)
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Serum sodium within normal limits
Serum potassium, magnesium, and calcium (serum calcium corrected for hypoalbuminemia) within institutional normal limits. Subjects with electrolytes outside the normal range will be eligible if these values are corrected upon retesting following any necessary supplementation.
Sodium, potassium, phosphorus, magnesium and total calcium laboratory values within normal limits
Patients have the following laboratory values outside of the laboratory normal limits or cannot be corrected to within normal limits with supplements during screening: Potassium, Magnesium, Phosphorus, Total calcium (corrected for serum albumin)
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within institutional upper limit of normal (IULN) or corrected to within normal limits with supplements before first dose of study medication; (supplements used for this purpose to be approved by primary investigator [PI])
Potassium and calcium (corrected for albumin), within normal limits for the institution, or =< grade 1 if judged not clinically significant by the investigator
Serum potassium (corrected for serum albumin) must be within clinically relevant limits (e.g., a patient can be enrolled if a lab value may be outside the normal laboratory range but the abnormality is not clinically relevant or can be repleted)
Sodium (corrected for serum albumin) must be within clinically relevant limits (e.g., a patient can be enrolled if a lab value may be outside the normal laboratory range but the abnormality is not clinically relevant or can be repleted)
Magnesium (corrected for serum albumin) must be within clinically relevant limits (e.g., a patient can be enrolled if a lab value may be outside the normal laboratory range but the abnormality is not clinically relevant or can be repleted)
Phosphorus (corrected for serum albumin) must be within clinically relevant limits (e.g., a patient can be enrolled if a lab value may be outside the normal laboratory range but the abnormality is not clinically relevant or can be repleted)
Total calcium (corrected for serum albumin) must be within clinically relevant limits (e.g., a patient can be enrolled if a lab value may be outside the normal laboratory range but the abnormality is not clinically relevant or can be repleted)
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed)
Serum sodium within normal limits
Total calcium (corrected for serum albumin) within normal limits
Total calcium (corrected for serum albumin) within normal limits or corrected with supplements
Patients must have the following electrolyte values ? LLN (lower limit of normal) limits or corrected to within normal limits with supplements prior to the first dose of study medication:
Patients must have the following laboratory values (WNL = within normal limits at the local institution lab) or corrected to within normal limits with supplements prior to the first dose of study medication:\r\n* Potassium (WNL)\r\n* Phosphorus (WNL)\r\n* Calcium (WNL)
Serum calcium, magnesium, potassium within normal limits, or if outside of normal limits, must be deemed clinically insignificant by the investigator
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed; the use of denosumab [Xgeva] is permitted)
Total calcium (corrected for serum albumin) within normal limits (biphosphonate use for malignant hypercalcemia control is not allowed)
Uric acid within normal limits
Potassium, magnesium, and calcium (corrected for albumin) > normal limits for the institution
Potassium and calcium (corrected for albumin), sodium and magnesium within institutional normal limits
Magnesium within 0.85 to 1.25 * institutional normal limits, Sodium greater than or equal to 130 milli equivalent per liter, Potassium within institutional normal limits (within 14 days prior to Day 1 of Cycle 1 up until pre-dose of Cycle 1)
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed)
Total calcium (corrected for serum albumin) within normal limits (bisphosphonate use for malignant hypercalcemia control is not allowed)
Sodium, potassium, phosphorus, magnesium and total calcium laboratory values within normal limits
The following laboratory values must be within normal limits prior to starting study drug (supplementation allowed): potassium, magnesium, total calcium (corrected for serum albumin), phosphorous
Serum electrolytes within normal limits: potassium, calcium (total, or corrected for serum albumin in case of hypoalbuminemia) and magnesium. If outside of normal limits, subject will be eligible when electrolytes are corrected;
Corrected calcium within normal limits, previous hypercalcemia allowed
Potassium, total calcium (corrected for serum albumin), magnesium, sodium and phosphorus within normal limits for the institution or corrected to within normal limits with supplements before first dose of study medication
Patients must have the following electrolyte values within normal limits or corrected to be within normal limits with supplements prior to first dose of study medication: