Measured creatinine clearance (CL) > 40 mL/min OR calculated creatinine clearance (CL) > 40 mL/min as determined by Cockcroft-Gault (using actual body weight)
Creatinine clearance of > 60 ml/min; creatinine clearance may be measured or calculated; if calculating, creatinine clearance, use the Cockroft-Gault formula =< 2 weeks prior to randomization
Creatinine clearance >= 30 mL/min/1.73 m^2 by Cockcroft-Gault OR creatinine < 1.5 x ULN, within 2 weeks of randomization
Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula, must be obtained within 8 weeks prior to screening for protocol therapy
ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula
Serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min using the following Cockcroft-Gault Formula within 28 days prior to sub-study registration
Re-registration: creatinine =< 1.5 ULN OR calc. creatinine clearance > 45 mL/min (using lean body mass formula only)
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance > 50 mL/min (using the Cockcroft-Gault formula) must be obtained =< 7 days prior to protocol registration
Within 2 weeks prior to registration: Creatinine =< 1.5 x ULN or calculated (Cockcroft-Gault formula) or measured creatinine clearance >= 50 mL/min/1.73 m^2 (normalized to body surface area [BSA]) for patients with creatinine levels greater than 1.5 times the institutional normal
Calculated creatinine clearance must be > 60 ml/min using the Cockcroft-Gault formula within 4 weeks prior to randomization
Within 10 days of treatment initiation: Measured or calculated creatinine clearance >= 50 mL/min\r\n* Creatinine clearance should be calculated using modified Cockcroft-Gault equation (using ideal body mass [IBM] instead of mass). Direct measured creatinine clearance (i.e. 24h urine or other method) can be substituted if calculated creatinine clearance is thought to be inadequate per treating physician
Calculated creatinine clearance using cockroft Gault formula >/= 50 mL/min (see Appendix 1)
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance using Cockcroft-Gault formula >= 50 mL/min
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR, for subjects with creatinine levels > 1.5 x ULN, an estimated creatinine clearance of >= 40 mL/min calculated using the Cockcroft and Gault formula must be met within 28 days of C1D1
Obtained =< 14 days prior to registration: Calculated creatinine clearance >= 45 ml/min using the Cockcroft-Gault formula
Creatinine =< 1.5 ULN or calculated creatinine clearance* >= 50 mL/min\r\n* Calculate creatinine clearance using standard Cockcroft-Gault formula; creatinine clearance must be >= 50 mL/min to be eligible
Creatinine < 1.5 x ULN or creatinine clearance > 60 ml/min according to Cockcroft-Gault formula
Calculated or measured creatinine clearance of >= 30 mL/minute calculated using the Cockcroft and Gault formula
Serum creatinine ? 1.5 X upper limit of normal (ULN) OR calculated clearance ? 50 mL/min/1.73 m^2; if using creatinine clearance, actual body weight should be used for calculating creatinine clearance (e.g., using the Cockcroft-Gault formula); for subjects with a body mass index (BMI) > 30 kg/m^2, lean body weight should be used instead
Serum creatinine =< 1.5 x institutional ULN OR creatinine clearance >= 50 mL/min/1.73 m^2 by Cockcroft-Gault
Creatinine clearance > 60 Ml/min/1.73 m2 for patients with creatinine levels above ULN calculated using Calvert formula
Creatinine =< 1.5 x institutional upper limit of normal OR creatinine clearance >= 50 mL/min as determined by the Cockcroft-Gault formula
EXPANDED ACCESS COHORT: Creatinine clearance >= 50 mL/min (determined by the Cockcroft-Gault method) for participants with creatinine levels above 1.5 x institutional ULN
Obtained within 28 days prior to registration: Calculated creatinine clearance >= 60 cc/min (Cockcroft-Gault formula will be used to calculate creatinine clearance)
Serum creatinine within normal limits or calculated clearance > 60 mL/min/1.73 m^2 for patients with serum creatinine levels above or below the institutional normal value. If using creatinine clearance, actual body weight should be used for calculating creatinine clearance (eg. Using the Cockcroft-Gault formula). For patients with a Body Mass Index (BMI) > 30 kg/m^2, lean body weight should be used instead.
Creatinine =< 1.5 times upper limit of normal OR calculated creatinine clearance > 45 mL/min\r\n* Using the lean body mass formula only (Modified Cockcroft Gault)
Creatinine clearance ? 50 mL/min; the serum creatinine value used in the calculation must have been obtained within 28 days prior to registration using the modified Cockcroft-Gault formula
Calculated creatinine clearance >= 50 ml/min using the Cockcroft-Gault formula
Calculated creatinine clearance (using Cockcroft-Gault formula) > 45 mL/min, at the screening visit
Calculated creatinine clearance >= 30 mL/min using Cockcroft-Gault formula
Estimated creatinine clearance of >= 40 mL/min/1.73 m^2, calculated using the Cockcroft-Gault equation for adults and Schwartz formula for pediatric patients, for patients with creatinine levels above the institutional upper limit of normal
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 50 ml/min (by Cockroft-Gault formula)
Creatinine ?1.5 x ULN or creatinine clearance ?40 mL/min as calculated by the Cockcroft-Gault method
Serum creatinine < 1.5 x upper limit of normal (ULN) or calculated creatinine clearance of >= 45 cc/min using the Cockcroft-Gault formula
Creatinine clearance >= 50 mL/min/1.73 m^2 for patients with creatinine levels above 1.5 x institutional normal (using the Cockcroft Gault formula)
Serum creatinine =< 1.5 times institutional upper limit of normal (ULN), or calculated creatinine clearance >= 40 mL/min (per the Cockcroft-Gault formula) within 14 days prior to first dose of protocol-indicated treatment.
Creatinine clearance >= 51 mL/min (calculated using the Cockcroft-Gault formula), =< 5 days prior to C1D1
Calculated creatinine clearance >= 40 mL/min using the Cockcroft-Gault formula obtained within 14 days prior to initiating study treatment.
Calculated creatinine clearance > 40 mL/min as determined by Cockcroft-Gault (using actual body weight).
Serum creatinine < 1.5 x ULN or measured creatinine clearance (calculated using Cockcroft-Gault formula) > 40 ml/min
Cockcroft-Gault calculated creatinine clearance of >= 45 ml/min or creatinine =< 1.5 x ULN obtained =< 14 days prior to study initiation
Serum creatinine =< 1.5 X institutional ULN or creatinine clearance > 40 ml/min as calculated by the Cockcroft-Gault formula
Within 28 days prior to administration of study treatment: Creatinine clearance >= 51 mL/min, calculated using Cockcroft-Gault formula
Serum creatinine =< 1.5 x the upper limit of normal (ULN) or calculated creatinine clearance (by Cockcroft-Gault formula) >= 60 mL/min
Creatinine > 1.5 x within normal institutional ULN OR creatinine clearance >= 40 mL/min (using Cockcroft-Gault formula) for participants with creatinine levels above institutional ULN
Obtained =< 14 days prior to registration: Calculated creatinine clearance must be >= 45 ml/min using the Cockcroft-Gault formula
Serum creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance > 40 mL/min (if using the Cockcroft-Gault formula) within 14 days of registration
Calculated creatinine clearance >= 30 mL/min using the Cockcroft-Gault formula for subjects with creatinine levels > 2.0 x institutional ULN (obtained within three days prior to study treatment)
Calculated creatinine clearance of >= 60 cc/min using the Cockcroft-Gault formula
Serum creatinine =< 2 x upper limit of normal (ULN) or estimated creatinine clearance >/=30 ml/min as calculated using the Cockcroft-Gault formula.
Creatinine ?1.5 times the ULN and calculated creatinine clearance >60 mL/min (by Cockcroft Gault formula; see Appendix B);
Serum creatinine ? 1.5 times the ULN or creatinine clearance > 30 mL/min by Cockcroft-Gault formula
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 50 mL/min using Cockcroft-Gault formula for creatinine clearance calculation OR 24-hour urine creatinine clearance >= 50 mL/min
Calculated creatinine clearance >= 50 ml/min (using Cockcroft-Gault method)
Within 14 days prior to cycle 1 day 1 of treatment: Serum creatinine < 2.0 or >= 30 cc/min using a direct method or the Cockcroft-Gault formula
Creatinine clearance > 30 mL/min (calculated according to institutional standards or using Cockcroft–Gault formula)
Serum creatinine =< 2 x upper limit of normal (ULN) or creatinine clearance (calculated with the Cockcroft-Gault formula) >= 30 mL/min, within 30 days before study registration
Serum creatinine =< 1.5 x ULN or creatinine clearance (calculated with the Cockcroft-Gault formula) >= 40 mL/min, within 30 days before study registration
Acceptable renal function within 7 days defined as serum creatinine ? 2.0 times the institutional upper limit of normal (ULN) or calculated creatinine clearance ? 50 mL/min (by the Cockcroft Gault formula).
Calculated creatinine clearance must be >= 45 ml/min using the Cockcroft-Gault formula obtained =< 7 days prior to registration
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 by Cockcroft-Gault formula
Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 40 mL/min (obtained within 28 days prior to first study treatment)\r\n* Cockcroft-Gault formula will be used to calculate creatinine clearance
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min calculated using the formula of Cockcroft and Gault
Creatinine clearance >= 40 mL/min for patients with creatinine\r\n* Levels above institutional normal (calculated using the Cockcroft-Gault formula)
Creatinine clearance (calculated creatinine clearance by Cockroft-Gault using adjusted body weight if actual body weight is 20% greater than ideal is permitted) should be > 50 ml/min
Obtained =< 14 days prior to randomization: Calculated creatinine clearance must be >= 45 ml/min using the Cockcroft-Gault formula
Creatinine =< 1.5 x ULN or creatinine clearance > 50 mL/min (calculated by Cockcroft-Gault method)
Serum creatinine >= 1.5 x upper limit of normal (ULN) and creatinine clearance (by Cockcroft-Gault formula) < 60 mL/min
Creatinine within normal institutional limits OR creatinine clearance > 60 mL/min/1.73 m^2 by Cockcroft-Gault formula
PHASE I: Creatinine =< ULN OR creatinine clearance >= 51 mL/min (calculated using the Cockcroft-Gault formula) for patients with creatinine levels above institutional normal
PHASE II SCLC: Creatinine =< ULN OR creatinine clearance >= 51 mL/min (calculated using the Cockcroft-Gault formula) for patients with creatinine levels above institutional normal
UROTHELIAL CARCINOMA EXPANSION COHORT: Creatinine =< ULN OR creatinine clearance >= 51 mL/min (calculated using the Cockcroft-Gault formula) for patients with creatinine levels above institutional normal
mCRPC EXPANSION COHORT: Creatinine =< ULN OR creatinine clearance >= 51 mL/min (calculated using the Cockcroft-Gault formula) for patients with creatinine levels above institutional normal
Serum creatinine < 1.5 x ULN or creatinine clearance > 50 mL/min (by Cockcroft- Gault)
plasma creatinine ? 1.5 x upper limit of normal (ULN) for the institution or calculated clearance ? 60 mL/min (Cockcroft-Gault formula)
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min based on the standard Cockcroft and Gault formula obtained within 14 days of first treatment
Creatinine level within normal institutional limit, or creatinine clearance > 15 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal, calculated using the Cockcroft-Gault formula)
Within 14 days prior to study entry: Calculated creatinine clearance >= 40 mL/min using Cockcroft-Gault formula
Creatinine =< 1.5 x ULN OR calculated creatinine clearance >= 60 mL/min calculated by the Cockcroft-Gault formula
ARM A COHORT 1: Creatinine =< 1.5 x institutional ULN, or creatinine clearance >= 50 mL/min (calculated with the Cockcroft-Gault formula)
ARM B COHORT 2: Creatinine =< 1.5 x institutional ULN, or creatinine clearance >= 50 mL/min (calculated with the Cockcroft-Gault formula)
ARM B COHORT 3: Creatinine =< 1.5 x institutional ULN, or creatinine clearance >= 50 mL/min (calculated with the Cockcroft-Gault formula)
ARM C COHORT 4: Creatinine =< 1.5 x institutional ULN, or creatinine clearance >= 50 mL/min (calculated with the Cockcroft-Gault formula)
Serum creatinine =< 1.5 times the upper limit of normal or creatinine clearance > 30 mL/min by Cockcroft-Gault formula
Calculated creatinine clearance must be >= 50 ml/min using the Cockcroft-Gault formula
24 hour creatinine clearance or calculated (using the Cockcroft-Gault formula) creatinine clearance > 60 mL/min/1.73 m^2 (induction phase only)
RESEARCH PHASE INCLUSION CRITERIA: 24 hour creatinine clearance or calculated (using the Cockcroft-Gault formula) creatinine clearance > 60 mL/min/1.73 m^2 (induction phase only)
Must be met within 28 days of C1D1: Serum creatinine =< 1.5 x ULN or estimated creatinine clearance of >= 40 mL/min calculated using the formula of Cockcroft and Gault
Creatinine clearance > 30 mL/min (calculated according to institutional standards or using Cockcroft–Gault formula; subjects with requirement of hemodialysis will be excluded)
Creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min calculated using the formula of Cockcroft and Gault
PART 2: Calculated creatinine clearance using the Cockcroft-Gault formula or 24 hr urine creatinine clearance must be > 60 ml/min
Creatinine > 1.5 times the upper limit of normal (ULN) (unless creatinine clearance normal), or calculated creatinine clearance < 40 mL/min (using Cockcroft-Gault formula)
Patients must have a serum creatinine ? the institutional upper limit of normal OR a creatinine clearance ? 60 cc/min, measured or calculated (Cockcroft-Gault formula), obtained within 14 days prior to registration.
Creatinine within normal institutional limits OR creatinine clearance >= 50 mL/min/1.73 m^2 by Cockcroft-Gault formula
Serum creatinine ? 1.5 x ULN and/or creatinine clearance (calculated using Cockcroft-Gault formula, or measured) < 50 mL/min
Calculated creatinine clearance of >= 50 cc/min using the Cockcroft-Gault formula
Creatinine clearance (calculated using Cockcroft-Gault formula, or measured) < 45 mL/min
Calculated creatinine clearance of >= 55 cc/min using the Cockcroft-Gault formula
Renal: serum creatinine within normal limits; for patients with levels above the institutional normal value, the calculated corrected creatinine clearance must be ? 60 mL/min/1.73 m^2 using the Cockcroft-Gault formula corrected for the body surface area.
Within 14 days prior to randomization: Serum creatinine =< 1.5 x ULN or measured or calculated creatinine clearance >= 50 mL/min using the Cockroft-Gault formula for patients with creatinine levels > 1.5 x ULN for the lab
Creatinine clearance >= 50 mL/min (using Cockcroft-Gault)
Obtained ? 14 days prior to registration: calculated creatinine clearance must be ? 30 ml/min using the Cockcroft Gault formula
Creatinine ? 1.5 x upper limits of normal (ULN) OR calculated creatinine clearance ? 60 mL/min by Cockcroft-Gault formula
Serum creatinine performed within 3 weeks prior to starting study therapy must be =< 1.5 x ULN, or have calculated creatinine clearance (using Cockcroft-Gault formula) of >= 50 mL/minute
Calculated creatinine clearance must be >= 30 ml/min using the Cockcroft-Gault formula
To be performed within 28 days prior to day 1 of protocol therapy: Creatinine < 1.5 x ULN or creatinine clearance of >= 60 mL/min per the Cockcroft-Gault formula
Creatinine clearance >= 50; creatinine clearance must be calculated using Cockroft-Gault formula
Calculated creatinine clearance must be >= 50 ml/min using the Cockcroft-Gault formula, obtained =< 14 days prior to registration
Obtained within 30 days prior to registration: Estimated creatinine clearance 40 cc/min OR serum creatinine =< 1.5 x upper limit of normal (ULN)\r\n* Cockcroft-Gault formula will be used to calculate creatinine clearance
Serum creatinine =< 1.5 x institutional ULN (Cockcroft and Gault formula)
Creatinine clearance >= 60 mL/min/1.73 m^2 for participants with creatinine levels above institutional normal (derived by the Cockcroft-Gault formula)
Serum creatinine =< ULN or calculated creatinine clearance >= 35 mL/min using Cockcroft-Gault formula
Creatinine =< 1.5 x ULN OR calculated creatinine clearance >= 50 ml/min using the Cockcroft-Gault formula (obtained =< 14 days prior to registration)
Patients must have a serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min using the Cockroft-Gault formula
Creatinine clearance > 30 cc/min calculated using the Cockcroft and Gault (1976) formula or measured
Creatinine =< 1.5 ULN or calculated creatinine clearance >= 50 mL/min or 24-hour urine creatinine clearance >= 50 mL/min; calculated by the Cockcroft-Gault formula
Creatinine =< 1.5 x institutional/laboratory upper limit of normal (ULN) OR calculated creatinine clearance (Cockcroft-Gault formula) >= 50 ml/min OR 24-hour urine creatinine clearance >= 50 ml/min
Creatinine =< 1.5 times the upper limit of normal with creatinine clearance >= 50 mL/min using the modified Cockcroft-Gault method
Creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above ULN as calculated by Cockcroft-Gault
For patients receiving chemotherapy:\r\n* Within 14 days prior to registration, serum creatinine =< 1.5 mg/dL and calculated creatinine clearance >= 50 cc/min; both tests must be within these limits; the creatinine clearance should be calculated using the Cockcroft-Gault formula\r\n* Aspartate aminotransferase (AST) =< 2 times upper limit of normal (ULN)\r\n* Bilirubin =< 2 times ULN\r\n* Alkaline phosphatase, magnesium, blood urea nitrogen (BUN), and electrolytes must be obtained and recorded
Creatinine =< grade 1 OR creatinine clearance >= 40 mL/min/1.73 m^2 for patients with creatinine (Cr) above normal institutional limits; a calculated creatinine clearance by Cockcroft-Gault Formula is acceptable in lieu of a measured value
Calculated creatinine clearance >= 60 mL/min; the serum creatinine value used in the calculation must have been obtained within 28 days prior to registration; use the modified Cockcroft-Gault formula
Creatinine clearance < 30 ml/min within 21 days of initiation of protocol therapy; creatinine clearance will be the primary eligibility criteria in determining renal insufficiency; the Cockcroft-Gault formula should be used for calculating creatinine clearance values
Creatinine =< ULN (Common Toxicity Criteria [CTC] grade 0) OR calculated creatinine clearance (Cockcroft-Gault formula) >= 60 mL/min OR >= 50 mL/min by ethylenediaminetetraacetic acid (EDTA) creatinine clearance
Serum creatinine levels <= 1.5 * ULN, or calculated (by Cockcroft-Gault formula or other accepted formula) or measure creatinine clearance >=50 mL/min.
Patients must have a serum creatinine =< the IULN AND measured or calculated creatinine clearance >= 60 cc/min using the Cockroft-Gault formula
REGISTRATION #2 - PRIOR TO CONSOLIDATION CHEMOTHERAPY: Patients must have a serum creatinine =< (IULN) AND measured of calculated creatinine clearance >= 60 cc/min using the Cockroft-Gault formula
Patients must have a serum creatinine =< the IULN OR measured or calculated creatinine clearance >= 50 mL/min using the Cockcroft-Gault formula
Serum creatinine level ? ULN or creatinine clearance ? 50 ml/min for patients with creatinine levels above normal limits (creatinine clearance calculated by the Cockcroft-Gault formula, see Appendix II),
Calculated creatinine clearance < 45mL/min (0.75 mL/sec)using Cockroft-Gault formula
Calculated creatinine clearance must be >= 50 ml/min using the Cockcroft-Gault formula obtained =< 7 days prior to registration
Serum creatinine > 1.5 x upper limit of normal (ULN) and/or creatinine clearance (calculated using Cockcroft-Gault formula, or measured) < 50 mL/min
Serum creatinine ?1.5 x upper limit of normal or creatinine clearance >60 mL/min (measured or calculated by the Cockcroft-Gault formula) (Cockcroft DW et al, 1976).
Calculated creatinine clearance must be >= 50 ml/min using the Cockcroft-Gault formula or a 24 hour urine obtained =< 7 days prior to randomization
Creatinine clearance > 30 cc/min calculated using the Cockcroft and Gault (1976) formula or measured
Serum creatinine, ? 1.5x Institutional Upper Limit of Normal (ULN), or Creatinine Clearance ? 50 mL/min (by Cockcroft-Gault formula)
Creatinine clearance > 50 ml/min, calculated using the formula of Cockcroft and Gault
Serum creatinine ? 1.5 x ULN or calculated creatinine clearance (using Cockcroft and Gault method) > 60 mL/min)
Serum creatinine =< 1.5 x ULN; or calculated creatinine clearance >= 50 mL/min (using Cockcroft Gault formula); or measured creatinine clearance >= 50 mL/min
Creatinine clearance > 30 mL/min (calculated according to institutional standards or using Cockcroft–Gault formula; subjects with requirement of hemodialysis will be excluded)
Calculated creatinine clearance must be >= 45 ml/min using the Cockcroft-Gault formula
Serum creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance of >= 40 mL/min by Cockcroft-Gault formula
Creatinine clearance > 50 mL/minute within 7 days of time of consent, either measured or calculated using a standard formula (e.g., Cockcroft and Gault)
Calculated creatinine clearance must be > 60 ml/min using the Cockcroft-Gault formula
Creatinine clearance of ? 50 mL/min (measured or calculated using the Cockcroft and Gault formula)
Calculated or measured creatinine clearance of >= 50 mL/minute, calculated using the formula of Cockcroft and Gault
Creatinine =< 1.5 x ULN or calculated creatinine clearance >= 50 mL/min calculated by the Cockcroft-Gault formula or 24-hour urine creatinine clearance >= 50 mL/min
Cockcroft-Gault calculated creatinine clearance of >= 45 ml/min or creatinine =< 1.5 x ULN obtained =< 14 days prior to randomization
Serum creatinine >1.5x ULN or creatinine clearance <40 mL/min (Cockroft-Gault formula) Exclusion Criteria for Arm S and Arm P only:
Creatinine clearance >= 30 mL/min as measured using either the Cockcroft-Gault method or 24-hour creatinine clearance
Calculated creatinine clearance > 50 ml/min using Cockcroft-Gault formula
All patients must: Have biopsy proven cancer (i.e. solid tumor) for which there is no standard therapy available. If prior history of ischemic heart disease or exposure to > 200 mg/m^2 of doxorubicin, patients must have a measured ejection fraction (either by MUGA, ECHO or ventriculography) of at least 45%. Have preserved hepatic function as shown by AST (SGOT) levels < 2 x the upper limit of normal and an INR (for patients NOT on anticoagulant therapy) of < 1.4. Have normal serum creatinine (<=1.5) or creatinine clearance (measured by Cockcroft -Gault formula) of >= 20 ml/min.
Creatinine within normal institutional limits OR creatinine clearance >= 30 mL/min calculated using the formula of Cockcroft and Gault
Creatinine clearance > 30 ml/min (Cockcroft-Gault formula using ideal body weight)
Serum creatinine within normal limits or calculated clearance ? 50 mL/min/1.73 m2 for subjects with serum creatinine levels above or below the institutional normal value. If using creatinine clearance, actual body weight should be used for calculating creatinine clearance (eg, using the Cockroft-Gault formula). For subjects with a body mass index (BMI) > 30 kg/m2, lean body weight should be used instead.
Serum creatinine =< 1.5 x the ULN or calculated creatinine clearance >= 50 ml/min using Cockcroft-Gault formula
Serum creatinine =< 1.5 x ULN or 24-hour creatinine clearance > 60 mL/min (measured or calculated by Cockcroft-Gault method)
Serum creatinine ?1.5 x upper limit of normal (ULN) or creatinine clearance >60 mL/min calculated using Cockcroft-Gault
Creatinine clearance >/=30 milliliters per minute (mL/min) (calculated using the Cockcroft-Gault formula)
Serum creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance > 40 ml/min using the Cockcroft-Gault formula should be obtained with 28 days prior to randomization
Plasma creatinine =< 1.5 x ULN or creatinine clearance > 50 mL/min (calculated by Cockcroft-Gault method)
Creatinine < 1 X institutional upper limit of normal OR creatinine clearance >= 50 mL/min determined by Cockcroft-Gault formula
Creatinine clearance > 30 mL/min (calculated according to institutional standards or using Cockcroft–Gault formula), +/- 7 days from date of ICF signing
Calculated creatinine clearance must be >= 50 ml/min using the Cockcroft-Gault formula
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance >= 60 cc/min using the Cockcroft-Gault formula
Calculated creatinine clearance must be >= 50 ml/min using the applicable Cockcroft-Gault formula
Creatinine* < 2.0 g/dl *or a calculated creatinine clearance > 45/cc (using Cockroft-Gault formula)
Calculated creatinine clearance ? 45 mL using the Cockcroft and Gault Method
Serum creatinine =< 1.5 x ULN OR creatinine clearance >= 50 mL/min (Cockcroft-Gault calculation)
Renal impairment as determined by a creatinine clearance < 60 ml/min as calculated by the Cockcroft-Gault formula using the patient's actual weight
Creatinine clearance > 15 ml/minute using Cockcroft-Gault formula
Creatinine clearance 45 ml/min or higher calculated using the Cockcroft-Gault formula
Creatinine clearance >= 30 mL/min calculated using the Cockcroft-Gault formula (within four weeks prior to the study)
Calculated (e.g. using Cockcroft-Gault formula) or measured creatinine clearance < 50 ml/min
Calculated creatinine clearance >= 50 ml/min by Cockcroft-Gault formula using actual body weight
Calculated creatinine clearance >= 50 mL/min using the Cockcroft-Gault formula
Calculated (calc.) creatinine clearance >= 60 mL/min calculated using the Cockcroft-Gault formula
Calculated creatinine clearance > 40 ml/min using Cockcroft-Gault method
Obtained =< 30 days prior to randomization: Calculated creatinine clearance must be >= 30 ml/min using the Cockcroft-Gault formula
Creatinine within normal institutional limits OR creatinine clearance >= 60 mL/min using the modified Cockcroft-Gault formula
Calculated creatinine clearance must be >= 30 ml/min using the Cockcroft-Gault formula obtained =< 30 days prior to registration
Obtained within 28 days prior to registration: Serum creatinine =< 1.5 x upper limit of normal (ULN) OR calculated creatinine clearance >= 40 mL/min (Cockcroft-Gault formula will be used to calculate creatinine clearance)
Creatinine =< 1.5 times the upper limit of normal with creatinine clearance >= 50 mL/min using the modified Cockcroft-Gault method
Serum creatinine =< 1.5 x ULN or measured calculated creatinine clearance >= 40 ml/min for subject with creatinine levels > 1.5 x institutional ULN (per Cockcroft-Gault formula) obtained =< 14 days prior to registration
Calculated creatinine clearance >= 30 mL/min using the Calvert Formula
Calculated/estimated or measured creatinine clearance at least 50 ml/min; note: creatinine clearance should be calculated using the Cockcroft-Gault formula; patients who will receive pemetrexed/cisplatin therapy must be obtained within 2 weeks of registration
Creatinine < 1.5 x ULN. If >1.5 x ULN, patient may still be eligible if calculated creatinine clearance >50 mL/min (0.83mL/s) as calculated by the Cockcroft-Gault method.