Adequate bone marrow, cardiac, kidney and liver function Adequate bone marrow, kidney, and liver function Prior SOT of kidney, liver, heart, lung, pancreas, small bowel, or any combination of these Adequate bone marrow, kidney and liver function Adequate bone marrow, kidney and liver function Adequate bone marrow, liver and kidney function Participants have adequate bone marrow, kidney and liver function. Adequate performance status and hematological, liver, and kidney function Adequate bone marrow, kidney and liver function Good kidney and liver function Adequate bone marrow, cardiac, kidney and liver function Severe impairment of your kidney or liver function Patients must have adequate bone marrow, kidney, and liver function, (within 14 days prior to registration), defined as: Must have adequate coagulation, hematology, kidney, and liver function, per protocol. Patient with bilateral LG UTUC may be enrolled if at least one side meets the inclusion criteria for the trial and if the other kidney does not require further treatments (The other kidney can be treated prior to the beginning of the study). Good kidney and liver function Normal liver, kidney and bone marrow function Must have adequate hepatic and kidney function. Adequate bone marrow, liver and kidney function Kidney function: creatinine < 2.5 x ULN. History of severe kidney disease (e.g chronic or acute kidney failure) with creatinine clearance below 30 and/or severe liver disease with liver tests over 4 times the upper normal level Patient with only 1 kidney History of kidney stones In cases of concern about decreased renal function and potential high radiation dose to the kidneys, an optional nuclear medicine kidney function scan may be performed prior to radiation therapy to determine the functional contribution of each kidney Significant liver, lung, heart, or kidney dysfunction Adequate hematological, liver and kidney function. Adequate hematological, liver, and kidney function Chronic kidney disease > stage 3. Adequate bone marrow, liver, kidney function Adequate bone marrow, kidney, and hepatic function (no laboratory value > 2 times the normal limit) Adequate bone marrow, kidney and liver function Patients must have adequate heart, kidney, liver and bone marrow function. Subject must have adequate kidney and liver function as described in the protocol Abnormal kidney function test results Adequate major organ function (normal or minimal alteration in liver, kidney, hematological, metabolic and cardiac function) Adequate hematological, liver and kidney function. Adequate hematologic, liver, coagulation and kidney function Adequate bone marrow, kidney and liver function Adequate liver, kidney, and bone marrow function Adequate bone marrow, kidney and liver function. Performance Status of 0 or 1 - Adequate bone marrow, kidney and liver function Active severe kidney or liver disease Adequate organ function (bone marrow, kidney and liver) Adequate kidney function Adequate liver, kidney, and bone marrow function Participants must have adequate liver, kidney, and bone morrow function Adequate hematological, liver and kidney function. Adequate glucose control, bone marrow, kidney, liver, and heart function. Patients with a solitary kidney Adequate bone marrow, kidney and liver function Severe impairment of your kidney or liver function Adequate bone marrow, kidney, liver, and heart function. Adequate blood, liver, and kidney function as defined by laboratory tests. Subjects must have adequate kidney function Adequate hematologic, kidney and liver function Adequate bone morrow and kidney function Adequate bone marrow, kidney and liver function Acceptable bone marrow, liver and kidney function. Adequate bone marrow, kidney, and liver function Inadequate functions of bone marrow, liver, and kidney. Has adequate organ function (bone marrow, kidney and liver) Have adequate cardiac, bone marrow, liver and kidney function Participants must have adequate hepatic and kidney function. Patients must have acceptable neutrophil and platelet counts as well as adequate kidney and liver function. Patients with recent history of kidney stones. Kidney tumor has been removed Adequate hematologic and organ function, including blood counts, liver and kidney function Stage I Arm A (GDC-0077): Normal kidney and liver function (lab results must be within 45 days prior enrollment) Solitary kidney No active kidney stones Chronic kidney disease or in participants without known kidney disease, estimated creatinine clearance of =< 30 ml/min, even after rehydration Any history of cardiovascular, kidney, or liver disease acute kidney injury Adequate bone marrow, liver and kidney function History of severe kidney disease (e.g. chronic or acute kidney failure) with creatinine clearance below 30 and/or severe liver disease with liver tests over 4 times the upper normal level Underlying kidney disease with a high risk of disease recurrence in the transplanted kidney Known chronic kidney disease (creatinine >= 3.0) Adequate hematological, liver and kidney function. Adequate bone marrow reserves and liver and kidney function, as assessed by the following laboratory requirements: Have adequate bone marrow reserves and liver and kidney function, as assessed by the following laboratory requirements: Have known history of kidney diseases Patients who have chronic kidney disease Renal (kidney) disease, or solitary kidney or have a history of kidney disease. Adequate performance status and hematological, liver, and kidney function Good kidney and liver function Adequate bone marrow, liver, and kidney function within 2 weeks prior to first dose Adequate function of kidney: Adequate bone marrow, kidney and liver function