Grade 2 or greater peripheral neuropathy Grade 2 or greater peripheral neuropathy Peripheral neuropathy of severity greater than grade 1 Peripheral neuropathy greater than or equal to Grade 2 Patients with greater than or equal to grade 2 peripheral neuropathy or active herpes infection Patients with grade 2 or greater neuropathy Grade 2 or greater neuropathy Current Grade greater than (>) 1 peripheral neuropathy by clinical examination Peripheral neuropathy grade 2 or greater Participants with baseline peripheral neuropathy greater than grade 2 Patients with greater than or equal to grade 2 peripheral neuropathy at baseline Grade 2 or greater neuropathy Have grade 2 or greater neuropathy at the time of screening Uncontrolled neuropathy grade 2 or greater, regardless of cause No prior evidence of grade 3 or greater ototoxicity or neuropathy Patients with peripheral neuropathy greater than grade II Has history of Grade 2 or greater peripheral neuropathy during the 3 months prior to enrollment. Patient has peripheral neuropathy of Grade 3 or greater intensity, or painful Grade 2, as defined by the NCI CTC. Patients with grade 2 or greater peripheral neuropathy. Grade II or greater neuropathy at baseline Subjects with grade 2 or greater neuropathy Peripheral neuropathy of severity greater than grade 1 Greater than grade 1 peripheral neuropathy at baseline Grade 2 or greater neuropathy Peripheral neuropathy grade 2 or greater Grade 2 or greater neuropathy [Applies to Phase 1]. Grade 3 or greater neuropathy [Applies to Phase 2]. Equal to or greater than grade 2 ataxia, cranial or peripheral neuropathy Grade 2 or greater neuropathy Patients must not have grade 2 or greater peripheral neuropathy Uncontrolled neuropathy grade 2 or greater regardless of cause. Peripheral neuropathy- grade 2 or greater Peripheral neuropathy grade 2 or greater Patients with grade 2 peripheral neuropathy or greater are excluded Equal to or greater than grade 2 ataxia, cranial or peripheral neuropathy Patients with grade II or greater peripheral neuropathy will be excluded from study Patients with greater than or equal to grade 2 peripheral neuropathy at baseline Peripheral neuropathy greater than Grade 1 No peripheral neuropathy greater than grade 1, due to any cause Greater than or equal to Grade-2 neuropathy Peripheral neuropathy of grade 2 or greater have persistent Grade 2 or greater toxicities from any cause (except alopecia or peripheral neuropathy). Severe neuropathy greater than or equal to grade 2 Peripheral neuropathy greater than grade 1 Grade 3 or greater edema (eg, peripheral, pulmonary) Patients with greater than 2 screening peripheral neuropathy Current peripheral neuropathy of NCI-CTC, version 4.0 Grade 3 or greater Grade 2 or greater peripheral neuropathy Peripheral neuropathy that is greater or equal to Grade 2 Has peripheral neuropathy that is greater or equal to Grade 2 The participant has any Grade 2 (or greater) peripheral neuropathy. No grade 2 or greater peripheral neuropathy. Peripheral neuropathy greater than or equal to grade 2. Peripheral neuropathy greater than grade 1 Peripheral neuropathy greater than grade 1