No history of severe cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity; examples would include unstable angina, recent myocardial infarction, oxygen-dependent pulmonary disease, and osteoarthritis requiring imminent joint replacement; moderate arthritis that does not preclude physical activity is not a reason for ineligibility
Ongoing restriction of physical activity with physician documentation
Has chest pain brought on by physical activity
Sedentary activity pattern (< 90 minutes per week of moderate-to-vigorous intensity sports activity) within the past year
Individuals reporting < 3 days/week of mild or moderate activity
Already using physical activity tracker or part of a physical activity program
Are willing to abstain from heterosexual activity or practice physical barrier contraception prior to time of study entry to 6 months after the last day of treatment
Having been treated with a total cumulative (lifetime) 131I therapeutic activity > 800 mCi (excluding 131I activity administered for diagnostic scans)
Inability to participate in physical activity because of co-morbidity or disability (e.g., severe arthritic conditions)
A history or presence of a comorbid disease for which diet modification and increased physical activity may be contraindicated or complicated
Willingness to change diet, physical activity and weight
Serum transaminases activity =< 3 x ULN
Exercise/physical activity contraindicated
Has given written consent prior to any trial-related activity is performed. (A trial-related activity is defined as any procedure that would not have been performed during the normal management of the patient).
Be willing to abstain from heterosexual activity or practice physical barrier contraception from study entry to 6 months after the last day of treatment
Endotoxin Activity Assay ? 0.60 EAA units
Sedentary defined as participating in 2 or less days of dedicated physical activity per week
Participates in 3 or more days of dedicated physical activity per week
Approval from their treating physician to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Approval from their treating physician to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Already walking or engaging in other physical activity > 120 minutes per week as documented via subject self-report
Unable to walk or engage in moderate-intensity physical activity
Baseline weight-bearing physical activity less than 150 min·wk^-1 using the Paffenbarger physical activity questionnaire
Any other condition that may impede testing of the study hypothesis, make it unsafe to engage in the physical activity program, or make the participant not available for end of study assessments (determined by the investigative team)
Able to initiate a supervised exercise program (free from any cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity)
Severe and/or uncontrolled comorbidity precluding safe participation in a physical activity program
Report of at least 90 minutes of mindfulness activity (e.g., meditation, yoga) per week
Medical clearance from an oncologist or primary care physician stating the participant is able to participate in an unsupervised, moderate-intensity physical activity program
Report < 150 minutes of weekly moderate-to-vigorous physical activity (MVPA) on the Global Physical Activity Questionnaire (GPAQ)
Physically able to engage in physical activity
Medical condition contraindicating physical activity participation
Participants must consume < 5 servings of fruits and vegetables per day and/or engages in < 150 weekly minutes of moderate to vigorous physical activity
Sedentary 6 months before the baseline visit defined as those individuals not participating in a regular exercise program or not meeting the minimal physical activity recommendations from the General Surgeon which is accumulating 30 minutes or more of moderate physical activity on most days of the week
Patient has severe disabilities limiting moderate physical activity, such as severe orthopedic conditions
Approval from the treating clinician to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Are willing to attempt increase in physical activity level
Survivors must not be performing >= 100 minute (min)/week of moderate-vigorous physical activity
Conditions that would interfere with the safety of moderate-to-vigorous intensity physical activity; participants will be screened for safety using the validated Physical Activity Readiness Questionnaire (PAR-Q)
Has chest pain brought on by physical activity
Regular participation in moderate- or vigorous-intensity physical activity for >= 30 minutes at least 5 times a week and strength training for >= 2 days
Primary physician consent to engage in physical activity unsupervised
Presence of cardiovascular disease that would make physical activity risky at the discretion of the provider
Moderate to highly active level of physical activity (e.g. currently participating in >= 60 minutes of moderate aerobic activity weekly)
Phase 2: CRC survivors 6 months or greater post-treatment, who additionally do not follow guidelines for physical activity (PA) (150 minutes of moderate to strenuous exercise weekly), and average, at least 6 hours/day of sedentary behaviors
The patient will also be provided with their own Philips Equivital® non-invasive, wearable activity monitoring device that will track activity and rest levels
Participants must have a baseline activity level of < 150 minutes/wk of moderate to vigorous activity as calculated using the moderate to vigorous components of the Leisure Time Exercise Questionnaire (LTEQ) for physical activity (completed during screening)
SUBJECT: Must be willing to register online and install the software to use an age-appropriate activity monitor and website, which will include sharing some personal identifiable information, to allow the participant to track their physical activity.
SUBJECT: Currently engaging in > 3 hours of moderate to vigorous physical activity per week, as reported in the exercise screening questions completed at the pre-study screening evaluation.
SUBJECT: Currently on or planning to begin active neoplastic therapy, as the side effects may significantly impair ability to participate in physical activity.
Sedentary, as defined as < 60 minutes of recreation or work requiring modest PA/week based on the 7 day physical activity recall questionnaire
Participants must also meet at least two of the following criteria related to lifestyle: 1) consume less than 3 servings of fruit and vegetable/day; 2) engage in less than 75 minutes moderate/vigorous activity per week, defined as anything that causes small increases in breathing or heart rate for a sustained amount of time (e.g., brisk walking, bicycling); and 3) engage in a mind-body practice less than 4 times a month
Does not meet recommended guidelines for PA (< 100 min of moderate activity and < 75 min of vigorous activity per week)
Approval from their treating physician to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Unable to walk or engage in moderate-intensity physical activity
Currently physically active (> 90 minutes of moderate or vigorous physical activity per week) as determined by Leisure Score Index of Godin Leisure-Time Exercise Questionnaire [LSI])
Cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity; examples would include unstable angina, recent myocardial infarction, oxygen-dependent pulmonary disease, and osteoarthritis requiring imminent joint replacement; moderate arthritis that does not preclude physical activity is not a reason for ineligibility
Have been cleared by their provider to engage low to moderate intensity physical activities
Physician permission to engage in moderate-intensity physical activity
Major contraindication to fish oil i.e. hypersensitivity to fish/oil or physical activity
Patient reported regular participation in moderate- or vigorous-intensity physical activity for at >= 30 minutes at least 5 times a week and strength training for >= 2 days/week
Must not have engaged in a regular (> 3x/week, physical activity program in the last 6 months)
Physically capable to do the hula-based physical activity moderate and vigorous physical activity (MVPA)
Are able to pass the Physical Activity Readiness Questionnaire or participant provides a letter from their physician or nurse practitioner clearing them for study participation
No contradictions to exercise based on the Physical Activity Readiness Questionnaire (PAR-Q)
Sedentary: < 90 minutes/week of moderate-intensity (not exhausting, light perspiration, e.g. fast walking, tennis, easy bicycling, easy swimming, popular and folk dancing) physical activity during the preceding 2 months, and < 30 minutes/month of any high-intensity activity (heart beats rapidly, sweating, e.g. running, aerobics classes, cross country skiing, vigorous swimming, vigorous bicycling) in the past 2 months
CANCER PATIENT GROUP: Sedentary defined as < 60 minutes of recreation or work requiring modest physical activity (PA)/week
CANCER PATIENT GROUP: Ability to perform the level of physical activity assessed by the Physical Activity Readiness Questionnaire (PAR-Q)
NON-CANCER PATIENT GROUP: Ability to perform the level of physical activity assessed by the Physical Activity Readiness Questionnaire (PAR-Q)
Less than 120 minutes/week of physical activity
Approval from member of the treatment team to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Unable to walk or engage in moderate-intensity physical activity
Report more than 120 minutes/week of physical activity
Be inactive at baseline (< 150 minutes [min]/week of moderate physical activity)
Patients who have any condition that contradicts moderate to vigorous exercise; are unable to walk unassisted; or are already meeting the physical activity guidelines of 150 min/week (wk) of moderate physical activity
Phase 2 only: be currently sedentary (i.e., engage in < or = 60 minutes of purposeful moderate-intensity PA/week)
Participants answering ‘Yes’ to one or more of the questions on the physical activity readiness questionnaire (PAR-Q) will need to obtain approval from a physician before they can participate in the intervention
Patients must not be currently enrolled in an ongoing (participating for 6 months or longer) medically prescribed diet or physical activity regimen
Patients who have participated in a marathon, triathlon, or other endurance-related physical activity within the previous 24 months
Patients who have had surgery for weight loss\r\n* Note: women will not be excluded if their baseline lifestyle assessment indicates a healthy eating and moderate physical activity with the exception of the exclusion criteria above
At the time of consent, patient or parent/guardian reports less than 420 minutes of moderate to vigorous physical activity over the last week
< 30 minutes per day of self-reported moderate or vigorous physical activity (PA)
Moderately sedentary lifestyle (less than 120 minutes/week moderate intensity activity)
Answer “no” to all questions on the Physical Activity Readiness Questionnaire (PAR-Q)
Willingness to change diet, physical activity, and weight
Are currently enrolled in a physical activity and/or dietary clinical trial
Meet all the following criteria related to lifestyle: a) consume less than 3 servings of vegetables (excluding any fried servings) and 1 serving of fruit (not including juice)/day; b) engage in less than 150 minutes moderate/vigorous intensity activity per week, defined as anything that causes small increases in breathing or heart rate for a sustained amount of time (e.g., brisk walking, bicycling); c) engage in a mind-body practice less once per week
Able mentally and physically to participate in interventions in this study (Note: If there are one or more positive responses to the Physical Activity Readiness Questionnaire [PARQ], then a physician-release for exercise is required prior to obtaining consent)
Not adherent to the standard for > five servings of fruits and vegetable and 150 minutes of physical activity
Has physical limitations and cannot participate in physical activity
Potential participants must be underactive (defined as participating in moderate or vigorous PA two days per week or less for 30 minutes or less each day)
A medical condition that precludes moderate-vigorous physical activity as determined by health care provider
Currently physically inactive; using the international physical activity questionnaire (IPAQ) short form physically inactive will be defined as scoring a 0 in both the moderate and vigorous activity questions, and engaging in walking that is =< 420 minutes per week
Cleared to participate in moderate intensity exercise by:\r\n* Answering “no” to all questions of the physical activity readiness questionnaire (PAR-Q), with the exception of current use of prescription medications, which is permitted\r\n* Written clearance from primary care practitioner
Cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity
Subjects who are noted (upon initial online screening) to do 150 minutes or more of moderate level physical activity each week, get less than 8% of their calories from saturated fat, and eat more than 5 fruit and vegetable servings per day will not be eligible
Any condition that, in the investigators’ judgment, would contraindicate diet modification, increased physical activity, use of metformin, or otherwise interfere with participation in the trial
Medical, surgical or radiation oncologist agrees to subject participation in a diet and physical activity program.
Cardiovascular, respiratory or musculoskeletal disease or joint problems that preclude moderate physical activity. Moderate arthritis that does not preclude physical activity is not a reason for ineligibility.
Significant pulmonary, cardiovascular, orthopedic, or musculoskeletal problems that would, in their oncologist's judgment, limit their ability to participate in physical activity
interested in increasing their physical activity,
Contraindications to increasing physical activity including, but not limited to,
A history or presence of a comorbid disease for which diet modification and increased physical activity may be contraindicated
AIM 1: Not meeting national guidelines for aerobic physical activity (i.e., at least 150 minutes per week of moderate intensity aerobic physical activity)
AIM 2: Not meeting national guidelines for aerobic physical activity (i.e., at least 150 minutes per week of moderate intensity aerobic physical activity)
DISEASE CHARACTERISTICS:\n\n          -  Completely resected histologically confirmed adenocarcinoma of the colon\n\n               -  High-risk stage II disease, including one of the following:\n\n                    -  T4 lesions\n\n                    -  Less than 12 sampled lymph nodes\n\n                    -  Poorly differentiated histology\n\n               -  Stage III disease, defined as having at least one pathologically confirmed\n                  positive lymph node or one pathologically confirmed positive tumour deposit.\n\n               -  Synchronous primary colon cancer allowed\n\n          -  Adjuvant chemotherapy treatment for colon cancer with a 5-fluorouracil- based regimen\n             received with an intent to provide a complete course of treatment. While one current\n             standard is 24 weeks of treatment, patients who are pre-planned to receive a shorter\n             duration of chemotherapy, including as part of a research study will also be\n             permitted. The actual treatment received may be less than 24 weeks; participants must\n             have received a minimum of one treatment cycle.\n\n          -  Chemotherapy must have been completed (i.e. last dose received) a minimum of 60 days\n             and a maximum of 180 days prior to registration.\n\n          -  Carcinoembryonic antigen (CEA) ? 5 ?g/L\n\n          -  Current physical activity levels do not meet the recommended guidelines (? 150 minutes\n             of moderate-to-vigorous or ? 75 minutes of vigorous physical activity/week) as\n             calculated using the Leisure Time Exercise Questionnaire (LTEQ)\n\n          -  Completion of chest x-ray or CT, and CT, MRI or ultrasound of abdomen within 60 days\n             of registration; these imaging tests must not show evidence of metastatic or\n             locally-recurrent colon cancer.\n\n          -  No rectal cancer\n\n        PATIENT CHARACTERISTICS:\n\n          -  ECOG performance status 0-1\n\n          -  Absolute granulocyte count ? 1,000/mm³\n\n          -  Platelet count ? 100,000/mm³\n\n          -  Hemoglobin ? 100 g/L\n\n          -  Serum creatinine ? 1.5 times upper limit of normal (ULN)\n\n          -  Total bilirubin ? 1.5 times upper limit of normal (ULN)\n\n          -  Alkaline phosphatase < 2.5 times ULN\n\n          -  ALT < 2 times ULN\n\n          -  Not pregnant or planning to become pregnant within the next 3 years\n\n          -  Able (i.e., sufficiently fluent) and willing to effectively communicate with the\n             physical activity consultant affiliated with the originating cancer center\n\n          -  Able (i.e., sufficiently fluent in English or French) and willing to complete the\n             patient-reported outcome questionnaires, social determinants of exercise measurement,\n             health economics, and physical activity questionnaires and logs\n\n          -  Able to complete the baseline exercise test\n\n          -  No significant comorbid conditions precluding participation in a physical activity\n             program as determined by the investigator\n\n          -  Likely to participate in a physical activity program, as assessed by the investigator\n\n          -  No history of other malignancies, except adequately treated nonmelanoma skin cancer,\n             curatively treated in situ cancer of the cervix, other solid tumors, Hodgkin lymphoma,\n             or non-Hodgkin lymphoma curatively treated with no evidence of disease for > 5 years\n\n        PRIOR CONCURRENT THERAPY:\n\n          -  See Disease Characteristics\n\n          -  No prior radiotherapy as a component of treatment for primary tumor\n\n          -  No concurrent treatment with additional chemotherapy or radiation\n\n          -  No concurrent treatment with any medications deemed by the investigator as likely to\n             preclude participation in a physical activity program\n\n          -  No concurrent anticancer treatment including chemotherapy, biological, or targeted\n             agents
Sedentary baseline lifestyle, with an average of < 180 minutes/week of moderate-intensity aerobic activity