Alkaline phosphatase =< 1.5 x the institutional ULN
Alkaline phosphatase (ALK Phos) =< 2.5 x institutional ULN
Alkaline phosphatase =< 1.5 x IULN within 28 days prior to registration
Within 6 weeks prior to randomization: Alkaline phosphatase must be =< 2.5 x ULN for the lab
Alkaline phosphatase =< 2.5 x ULN (CTCAE v 3.0 grade 0-1)
Alkaline phosphatase =< 3 x ULN
Alkaline phosphatase =< 1.5 x institutional ULN, within 21 days prior to registration
Alkaline phosphatase =< 2 x IULN
Patients must have alkaline phosphatase =< 2.5 x IULN within 14 days prior to registration
Alkaline phosphatase less than or equal to 2.5 x ULN (CTCAE grade 1)
Alkaline phosphatase =< 3X the institutional ULN
Alkaline phosphatase ? 2.5 x ULN, unless the elevated alkaline phosphatase is due to bone metastasis.
Alkaline phosphatase ? 2.5 × ULN;
Alkaline phosphatase =< 2 × ULN (=< 5 × ULN if considered due to tumor)
Alkaline phosphatase < 5 times ULN
AST and/or ALT > 1.5 x ULN with concomitant alkaline phosphatase > 2.5 x ULN
Serum alkaline phosphatase =< 5 x institutional ULN
Alkaline phosphatase =< 3 × ULN
Alkaline phosphatase > 3 ULN
Alkaline phosphatase should be less than or equal to 2.5 x ULN (CTCAE v4.0, grade 1)
Have an alanine aminotransferase (ALT) ?3.0 × ULN. (Note: There are no specific requirements for AST or alkaline phosphatase.)
alkaline phosphatase must be ? 2.5 x ULN for the lab; and
Alkaline phosphatase =< 2.5 x ULN; (=< 5 x ULN in case of bone metastasis)
Alkaline phosphatase =< 2.5 x ULN, within 14 days prior to registration
Alkaline phosphatase =< 2.5 x ULN
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 2.5 x upper limit of normal (ULN) with alkaline phosphatase =< 2.5 x ULN OR AST and ALT =< 1.5 x ULN, with alkaline phosphatase > 2.5 x ULN
ARM 2 - A: AST/ALT/alkaline phosphatase: =< 5 x ULN
Alkaline phosphatase =< 3 x ULN =< 28 days prior to registration
Alkaline phosphatase up to 2.5 x ULN.
COHORT B ONLY: Obtained =< 14 days prior to registration: alkaline phosphatase =< 750 U/L
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase less than 1.5 times ULN (grade 1)
Alkaline phosphatase =< 2.5 x ULN
ALT or aspartate AST > 1.5 x ULN concomitant with alkaline phosphatase > 2.5 x ULN
AST and ALT =< 1.5 x ULN, with alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase < 2.5 × ULN
Serum alkaline phosphatase =< 5 X ULN
Obtained =< 14 days prior to registration: Alkaline phosphatase =< 3 x ULN
Alkaline phosphatase =< 2.5 x ULN for the institution within 14 days of study registration
Alkaline phosphatase less than or equal to 2.5 x ULN (CTCAE v4.03 grade 1)
Alkaline phosphatase =< 5 x ULN must be met during screening (within 21 days) and also prior to study drug administration on cycle 1 day 1
Within 14 days prior to registration: Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase < 4 x ULN.
Alkaline phosphatase (alk phos) < 2.5 X ULN
Alkaline phosphatase =< 2.5 X ULN
Alkaline (Alk) phosphatase < 2.5 x ULN
Hepatic impairment, defined as alkaline phosphatase =< 2 x institutional ULN, within 21 days of initiation of protocol therapy
Hepatic impairment, defined as alkaline phosphatase > 2 x institutional ULN, within 21 days of initiation of protocol therapy
Alkaline phosphatase =< 3 x ULN
Determined within 3 weeks of treatment initiation: Alkaline phosphatase < 5 x ULN
Alkaline phosphatase =< 2.5 x ULN prior to biopsy
Obtained =< 7 days prior to registration: Alkaline phosphatase < 5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase < 3 x ULN
Alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase =< to 2.5 x ULN
Alkaline phosphatase < 5 x ULN obtained =< 7 days prior to registration
Alkaline phosphatase =< 2.5 x institutional ULN obtained within 14 days of first treatment
Alkaline phosphatase =< 2.5 x ULN, unless elevation is thought to be due to hepatic infiltration by the hematologic malignancy
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase (Alk phos) =< 5 X ULN
Alkaline Phosphatase less than 2.5 x ULN (CTCAE Grade 1)
Alkaline phosphatase (liver fraction) =< 2.5 X ULN; if AST or ALT is > 2.5 X ULN, then liver fraction of alkaline phosphatase should be =< 2.5 X ULN
Alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase (AP) ? 2.5 x ULN, unless considered due to organ leukemic involvement;
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) < 2.5 x upper limit of normal (ULN) with alkaline phosphatase =< 2.5 x ULN OR AST and ALT =< 1.5 x ULN, with alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase (alk phos) < 2.6 x ULN
Alkaline phosphatase =< 1.5 x ULN, obtained =< 14 days prior to registration
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 ULN
Alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase < 2.5 x ULN
Serum alkaline phosphatase =< 5 x ULN
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase =< 2 x ULN or considered not clinically significant
Obtained =< 14 days prior to registration: Alkaline phosphatase =< 750 U/L
Alkaline phosphatase ?2.0×ULN.
Alkaline phosphatase ?5 x ULN
ORAL CAVITY SQUAMOUS CELL CARCINOMA COHORT: Alkaline phosphatase < 2 x ULN
Alkaline phosphatase < 2.5 X ULN
Alkaline phosphatase < 252 u/L
Alkaline phosphatase < 2.0 x ULN
Alkaline phosphatase must be =< 3 x ULN for the lab within 28 days before randomization
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase (ALK Phos) < 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN; if liver involvement, alkaline phosphatase =< 5.0 x ULN
Alkaline phosphatase =< 2.5 x ULN for the institution
Alkaline phosphatase must be =< 2.5 x ULN for the lab
Alkaline phosphatase and AST may not both be > the ULN; for example, if the alkaline phosphatase is > the ULN but =< 2.5 x ULN, the AST must be =< the ULN; if the AST is > the ULN but =< 1.5 x ULN, the alkaline phosphatase must be =< ULN; Note: If alanine aminotransferase (ALT) is performed instead of AST (per institution's standard practice), the ALT value must be =< 1.5 x ULN; if both were performed, the AST must be =< 1.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase less than or equal to 2.5 x ULN (CTEP CTCAE version 4.0, grade 1)
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase >= 2 x institutional ULN, within 21 days of initiation of protocol therapy
Alkaline phosphatase =< 2.5 x upper limit of normal (ULN); patients with hepatic and/or bone metastases: alkaline phosphatase =< 5 x ULN
Alkaline phosphatase >= 2 x ULN
Alkaline phosphatase =< 2 x IULN be obtained within 42 days prior to registration
Alkaline phosphatase =< 1.5 x ULN (institutional)
Alkaline phosphatase ? 5 x ULN
Alkaline phosphatase =< 2.5 x ULN for the institution
Alkaline phosphatase less than or equal to 2.5 x ULN
Alkaline phosphatase greater than 2.5 x ULN (CTCAE v4.0 grade 1) (if known hepatic metastases alkaline phosphatase may be =< 5 x ULN)
Alkaline phosphatase* less than or equal to 2.5 x ULN
Alkaline phosphatase =< 1.5 UNL
alkaline phosphatase must be less than or equal to 2 x ULN; and
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase ?2.0×ULN
Alkaline phosphatase limit ? 2.5 x ULN
Alkaline phosphatase less than or equal to 3 x ULN
Alkaline phosphatase less than or equal to 2.5 x ULN
Alkaline phosphatase < or equal to 4 x ULN if not related to leukemic disease
Alkaline phosphatase ? 2.5 x ULN
Alkaline phosphatase within 5 times ULN
Alkaline phosphatase ? 5X ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline (Alk.) phosphatase =< 3 x ULN
Alkaline phosphatase: ? 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN obtained =< 14 days prior to registration
Alkaline phosphatase > 3 x institutional ULN, within 21 days of initiation of protocol therapy
Alkaline phosphatase =< 3 x ULN
Alkaline phosphatase (AP) =< 2.0 x ULN
Alkaline phosphatase < 2 X institutional ULN
Alkaline phosphatase < 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 5 x ULN
Alkaline phosphatase =< 5.0 x ULN
Alkaline phosphatase =< 1.5 x IULN
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase >= 2.5 times ULN
Alkaline phosphatase > 3 x ULN
Alkaline phosphatase > 2 x institutional ULN
Alkaline phosphatase =< 2.5 x ULN
Serum alkaline phosphatase should be =< 1.5 x institutional ULN
Alkaline phosphatase (Alk Phos) =< 2.5 x ULN
Alkaline (Alk) phosphatase < 2.5 x ULN
Obtained =< 7 days prior to registration: Alkaline phosphatase =< 3 x ULN
Alkaline phosphatase >= 3 x ULN
Alkaline phosphatase ? 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 X ULN
Alkaline phosphatase =< 2.5 x ULN for the institution
Alkaline phosphatase =< 2.5 x ULN, CTCAE grade 1
Alkaline phosphatase < 2.5 x ULN
Alkaline phosphatase no greater than 1.5 times ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase less than or equal to 2.5 x ULN
Alkaline phosphatase values within the institutional ULN
Alkaline phosphatase =< 2.5 X ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase < 2.5 x ULN
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and alkaline phosphatase must be within the eligible; in determining eligibility, the more abnormal of the two values (AST or ALT) should be used; patients with alkaline phosphatase elevation secondary to the bony metastases rather than liver dysfunction may proceed with treatment on protocol after discussion with the principal investigator
Alkaline phosphatase > 1 x ULN but =< 2.5 x ULN and AST or ALT =< ULN eligible
Alkaline phosphatase > 2.5 x ULN but =< 5 x ULN and AST or ALT =< ULN eligible
Alkaline phosphatase > 5 x ULN and AST or ALT =< ULN ineligible
Alkaline phosphatase =< ULN and AST or ALT > 1 x ULN but =< 1.5 x ULN eligible
Alkaline phosphatase > 1 x ULN but =< 2.5 x ULN and AST or ALT > 1 x ULN but =< 1.5 x ULN eligible
Alkaline phosphatase > 2.5 x ULN but =< 5 x ULN and AST or ALT > 1 x ULN but =< 1.5 x ULN ineligible
Alkaline phosphatase > 5 x ULN and AST or ALT > 1 x ULN but =< 1.5 x ULN ineligible
Alkaline phosphatase =< ULN and AST or ALT > 1.5 x ULN but =< 5 x ULN eligible
Alkaline phosphatase > 1 x ULN but =< 2.5 x ULN and AST or ALT > 1.5 x ULN but =< 5 x ULN ineligible
Alkaline phosphatase > 2.5 x ULN but =< 5 x ULN and AST or ALT > 1.5 x ULN but =< 5 x ULN ineligible
Alkaline phosphatase > 5 x ULN and AST or ALT > 1.5 x ULN but =< 5 x ULN ineligible
Alkaline phosphatase =< ULN and AST or ALT > 5 x ULN ineligible
Alkaline phosphatase > 1 x ULN but =< 2.5 x ULN and AST or ALT > 5 x ULN ineligible
Alkaline phosphatase > 2.5 x ULN but =< 5 x ULN and AST or ALT > 5 x ULN ineligible
Alkaline phosphatase > 5 x ULN and AST or ALT > 5 x ULN ineligible
Alkaline phosphatase less than or equal to 2.5 x ULN (CTCAE v4.0 grade 1)
Alkaline phosphatase < 3 x ULN
Alkaline phosphatase =< 2 X ULN
Alkaline phosphatase =< 2.5 times ULN
Alkaline phosphatase ? 2.5 times the ULN
Alkaline phosphatase =< 2.5 x ULN for the institution
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x IUNL
Alkaline phosphatase (AP) must be within the range allowing for eligibility, as follows:\r\n* =< ULN\r\n* =< 2.5 x ULN\r\n* =< 5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 3.0 x ULN; if liver involvement, alkaline phosphatase =< 5.0 x ULN
Alkaline phosphatase must be =< 2.5 x ULN for the lab
Alkaline phosphatase and AST/ALT may not both be > the ULN; for example, if the alkaline phosphatase is > the ULN but =< 2.5 x ULN, then the AST/ALT must be =< the ULN; if the AST/ALT is > the ULN but =< 1.5 x ULN, then the alkaline phosphatase must be =< ULN
Patients with AST/ALT or alkaline phosphatase > ULN must have liver imaging that does not demonstrate metastatic disease
Alkaline phosphatase above 2.5X the ULN
Alkaline phosphatase =< 5 x UNL
Alkaline phosphatase of =< 2 ULN
The subject has aspartate aminotransferase and/or alanine aminotransferase > 1.5 × ULN, with concomitant alkaline phosphatase > 2.5 × ULN.
Alkaline phosphatase limit =< 2.5 x ULN
Alkaline phosphatase (Alk phos) =< 3.0 x ULN
Alkaline phosphatase =< to 2.5 x ULN
Alkaline phosphatase =< 5 x institutional ULN obtained =< 7 days prior to registration
Part 2 only: plasma total bilirubin <= ULN; ALT and/or AST <= 1.5 X ULN concomitant with alkaline phosphatase <= 2.5 X ULN.
Part 2 only: Patients with plasma total bilirubin > ULN; ALT and/or AST > 1.5 X ULN concomitant with alkaline phosphatase > 2.5 X ULN.
Alkaline phosphatase =< 2.5 × ULN (patients with hepatic and/or bone metastases: alkaline phosphatase =< 5 × ULN)
Liver: hepatomegaly on physical exam with elevated alkaline phosphatase > 1.5 x ULN
Alkaline phosphatase ? 5 x ULN
Alkaline phosphatase < 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase =< 2.5 x ULN; except for patients with hepatic and/or bone metastases: alkaline phosphatase =< 5 x ULN
Alkaline phosphatase < 2 x ULN (< 5 x ULN in subjects whom the PI and sponsor agree that clinical data suggest extrahepatic source of elevation)
Alkaline phosphatase (AP) =/< 2.5 x ULN
Alkaline phosphatase less than or equal to 2.5 x ULN (CTCAE grade 1)
Alkaline phosphatase =< 1.5 x ULN
Alkaline phosphate =< 2.5 x ULN (within four weeks prior to the study)
Alkaline phosphatase < 2 times ULN, unless arising from bone
Alkaline phosphatase =< 5 x ULN
Alkaline phosphatase =< 2.5 x ULN
Alkaline phosphatase limit =< 2.5 x ULN
Alkaline phosphatase < 2 times ULN, unless arising from bone
Alkaline phosphatase less than or equal to 2.5 x ULN
Alkaline phosphatase limit =< 2.5 x ULN
Serum alkaline phosphatase < 2 x ULN, or considered not clinically significant by the study doctor or designee
Alkaline phosphate > 1.5 x ULN
Patients with plasma alkaline phosphatase greater than 190 IU/dL
Alkaline phosphatase =< 2.5 x ULN
Serum alkaline phosphatase level >= 300 IU/L.
Alkaline phosphatase ? 2.5 x ULN
Alkaline phosphatase < 5 x ULN
Alkaline phosphatase < 4 x ULN
Alkaline phosphatase =< 1.5 x ULN
Alkaline phosphatase < 2 x ULN
Alkaline phosphatase < 2 x ULN
Alkaline phosphatase =< 1.5 x institutional ULN
Alkaline phosphatase > 2.5 x ULN
Alkaline phosphatase < 2.5 x ULN
Alkaline phosphatase =< 2.5 time ULN
Alkaline phosphatase =< 2 X ULN
Alkaline phosphatase =< 2.5 x IULN
Alkaline phosphatase (ALK phos) within 2 x ULN
Alkaline phosphatase =< 2.5 x IULN
Alkaline phosphatase (AP) =< 3 X ULN, obtained within 14 days prior to PET scan
Alkaline phosphatase < 3 x ULN
Alkaline phosphatase =< 5 x ULN
Alkaline phosphatase < 2.5 x ULN
Alkaline phosphatase =< 190 IU/dL
Patients with plasma alkaline phosphatase greater than 190 IU/dL
Alkaline phosphatase ? 2.5 x ULN