Must have creatinine ? 1.5 × institutional ULN or Creatinine Clearance > 50 ml/min (as calculated by the Cockcroft-Gault equation) within 14 days prior to randomization.
Serum creatinine =< 1.5 X institutional ULN and creatinine clearance >= 60 ml/min\r\n* NOTE: creatinine clearance must be calculated using the Cockcroft-Gault equation
Calculated creatinine clearance >= 45 mL/min by Cockcroft-Gault equation
Within less than or equal to 14 days prior to registration: Serum creatinine =< 1.5 X institutional ULN and creatinine clearance >= 60 ml/min\r\n* NOTE: Creatinine clearance must be calculated using the Cockcroft-Gault equation
Creatinine clearance >= 25 ml/min (using the Cockcroft-Gault equation), documented within 14 days of registration
Estimated creatinine clearance of > 50 ml/min (0.84 mL/s) by the Cockcroft-Gault equation
Subject has adequate renal function with an estimated creatinine clearance of ? 30 mL/min by the Cockcroft-Gault equation adjusted for body weight
Calculated creatinine clearance (CrCl) >= 50 mL/min (based upon the Cockcroft-Gault equation)
Calculated creatinine clearance >= 30 mL/min as determined by the Cockcroft-Gault equation
Creatinine clearance >= 30 mL/min (Cockcroft-Gault equation)
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used, within 14 days before the first dose of cabozantinib
Estimated creatinine clearance (using Cockcroft-Gault equation) must be > 50 mL/min
Has adequate renal function, defined as: Creatinine clearance >= 60 mL/min, as calculated using the modified Cockcroft Gault equation, ([{140 - age in year
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 40 mL/min within 7 days before the first dose of cabozantinib. For creatinine clearance estimation, the Cockcroft and Gault equation should be used
Creatinine clearance >= 60 mL/min/1.73 m^2 (as estimated by Cockcroft Gault equation) for subjects with creatinine levels above institutional normal
Creatinine clearance >= 60 mL/min by Cockcroft-Gault equation for participants with creatinine levels above institutional normal, completed within 14 days prior to the date of registration
Estimated GFR > 45 ml/min using Cockroft-Gault equation
Creatinine clearance >= 45 ml/min (24 hour urine creatinine clearance or calculated by Cockcroft-Gault equation)
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min, obtained =< 14 days prior to registration
Calculated creatinine clearance ? 30 mL/min (using the Cockcroft-Gault equation).
Creatinine clearance (as calculated by Cockroft Gault equation >= 30mL/min
Calculated creatinine clearance (CrCl) >= 40 mL/min (based upon the Cockcroft-Gault equation)
Creatinine (CR) within the institutional limits of normal or a calculated creatinine clearance of >= 30 mL/min according to the Cockcroft-Gault equation
Calculated creatinine clearance >= 30 ml/min (by the Cockcroft-Gault equation)
Obtained =< 14 days prior to registration: Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min
Creatinine clearance (CrCl) >= 30 ml/min (Cockroft-Gault equation)
Creatinine clearance >= 60 mL/min by the Cockcroft Gault equation
Serum creatinine =< 1.5 x ULN or serum creatinine > 1.5 – 3 x ULN if calculated creatinine clearance (CrCl) is >= 30 mL/min using the Cockroft-Gault equation
Serum creatinine =< 1.5 x ULN or estimated creatinine clearance >= 50 mL/min as calculated using the Cockcroft-Gault (CG) equation.
Obtained ? 14 days prior to registration: Calculated creatinine clearance (using Cockcroft-Gault equation below) ? 30 mL/min
Creatinine clearance >= 30 ml/min based on the Cockcroft-Gault equation.
Adequate renal function, as indicated by modified Cockcroft-Gault equation (estimated creatinine clearance [eCCR] with the use of ideal body mass [IBM] instead of mass)
Estimated creatinine clearance (CrCL) using the Cockroft-Gault equation ? 50 mL/min
Creatinine ? 1.5 x institutional ULN or estimated creatinine clearance of ? 45 mL/min by the Cockcroft-Gault equation or measured creatinine clearance > 45 mL/min
Calculated creatinine clearance (CrCl) >= 40 mL/min (based upon the Cockcroft-Gault Equation)
Creatinine clearance < 50 mL/min/1.73 m2 by Cockcroft-Gault equation
Calculated creatinine clearance >= 60 ml/min (by the Cockcroft-Gault equation)
Obtained within 28 days prior to the first dose of cabozantinib: serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min. For creatinine clearance estimation, the Cockcroft and Gault equation should be used.
Adequate renal function (The Cockcroft-Gault equation will be used to estimate creatinine clearance. This equation is as follows: Creatinine clearance in ml/min = (140 - age) x body weight (kg)/72 x plasma creatinine (mg/dL); multiplied by 0.85 for women. Using this equation, adequate renal function will be deemed to be a creatinine clearance of greater than 60 ml/minute.)
Within 7 days prior to administration of study treatment: Calculated creatinine clearance (Cockcroft-Gault equation) >= 40 mL/min.
Creatinine =< 2 mg/dL or creatinine clearance (as estimated by Cockcroft Gault equation) >= 60 mL/min
Creatinine clearance >= 30 mL/min based on the Cockcroft-Gault equation
Within 7 days before the first dose of study treatment: Serum creatinine =< 1.5 x the ULN or creatinine clearance (CrCl) >= 40 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Alanine aminotransferase (ALT) =< 2.5 x ULN; and estimated creatinine clearance (CrCl) of > 30 mL/min, as calculated by the Cockcroft-Gault equation.
Obtained =< 14 days prior to registration: Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min
Creatinine =< 1.5 x institutional ULN or estimated creatinine clearance of >= 45 mL/min by the Cockcroft-Gault equation or measured creatinine clearance > 45 mL/min
Serum creatinine =< 2.0 X institutional upper limit of normal or creatinine clearance >= 50 mL/min (according to the Cockroft and Gault equation)
Serum creatinine =< 1.5 x ULN or estimated creatinine clearance >= 50 ml/min by Cockcroft-Gault equation
Creatinine clearance (calculated per Cockcroft-Gault equation) >= 60 mL/min for participants with creatinine levels above institutional normal
Calculated creatinine clearance < 30 ml/min according to Cockcroft-Gault equation Other exclusion criteria included in the protocol might apply.
Calculated creatinine clearance >= 30 mL/min using the Cockcroft-Gault equation
Creatinine clearance > 50 mL/min/1.73 m^2 by Cockcroft-Gault equation
Creatinine clearance > 30 mL/min based on the Cockcroft-Gault equation
Participants must have creatinine clearance estimated using the Cockcroft-Gault equation of >= 51 mL/min, measured within 28 days prior to administration of study treatment\r\n* Note: patients with creatinine clearance between 51- 80 mL/min either at trial enrollment or during the course of the trial should be monitored every 2 weeks for laboratory assessment and toxicity evaluation
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 60 mL/min (Cockcroft Gault equation)
Within 14 days of registration: Creatinine >= 51 mL/min estimated using the Cockcroft-Gault equation
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min, obtained =< 14 days prior to registration
Estimated creatinine clearance (CrCL) using the Cockcroft-Gault equation >= 50 mL/min
Serum creatinine =< 1.5 x ULN or estimated creatinine clearance >= 30 mL/min as calculated using the Cockcroft-Gault (CG) equation
Creatinine clearance >= 50 ml/min using a 24 hour creatinine clearance or estimated creatinine clearance using the Cockcroft-Gault equation
Creatinine =< 1.5 x ULN, serum creatinine clearance (CL) > 51 ml/min (by the Cockcroft- Gault equation)
Serum creatinine =< 1.5 mg/dL or calculated creatinine clearance >= 50 mL/min using the Cockcroft-Gault equation
Creatinine clearance >= 30 mL/min/1.73 m^2 (as determined by Cockcroft-Gault equation) obtained =< 14 days prior to registration
Creatinine clearance < 50 cc/min measured or calculated by Cockroft-Gault equation
Calculated creatinine clearance (CCr) >= 50 mL/min/1.73^2 using the Cockcroft-Gault equation
Serum creatinine clearance (CrCl) ? 30 mL/min using the Cockcroft- Gault equation
Or creatinine clearance ? 60 mL/minute for subjects with serum creatinine outside the normal range (calculated using the Cockcroft-Gault equation).
Calculated creatinine clearance (Cockcroft-Gault equation) >= 40 mL/min
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 60 mL/min
Serum creatinine =< 1.5 mg/dL or creatinine clearance greater or equal than 40 cc/min as defined by the Cockcroft-Gault equation
Serum creatinine =< 1.5 mg/dL or creatinine clearance >= 60 mL/min as estimated by the Cockcroft-Gault equation
Creatinine > 1.5 times ULN or an estimated creatinine clearance < 50 mL/minute calculated using the Cockcroft-Gault equation
Creatinine clearance (CrCl) >= 30 mL/min (as calculated by Cockcroft-Gault equation)
Creatinine clearance >= 50 mL/min (by Cockcroft?Gault equation)
Creatinine =< 1.5 mg/dL or creatinine clearance > 30 ml/min (estimated as calculated with Cockcroft-Gault equation)
Creatinine clearance of < 50 ml/minute by Cockcroft Gault equation
Creatinine clearance >= 45 mL/min as calculated by the standard Cockcroft-Gault equation using age, actual weight, creatinine and gender
Creatinine clearance greater than or equal to (>=) 60 milliliter per minute (mL/min) either as estimated by the Cockcroft-Gault equation or based on urine collection (12 or 24 hours).
Has adequate renal function, defined as: Creatinine clearance >=60 mL/min, as calculated using the modified Cockcroft Gault equation, ([{140 - age in year
Within 4 days prior to the first dose of cabozantinib: Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min (for creatinine clearance estimation, the Cockcroft and Gault equation should be used)
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance (CrCl) >= 50 ml/min based upon the Cockcroft-Gault equation
Serum creatinine =< 1.5 x ULN OR creatinine clearance (CrCl) >= 40 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Patients must have adequate renal function as evidenced by a serum creatinine ? 1.5 X ULN for the reference laboratory OR a calculated creatinine clearance of ? 60 mL/min by the Cockroft-Gault equation.
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Known chronic liver disease, end stage renal disease, or creatinine clearance < 30 mL/min as defined by Cockcroft-Gault equation
Serum creatinine =< 1.5 x ULN or estimated creatinine clearance >= 50 ml/min by Cockcroft-Gault equation
Creatinine clearance (CrCL) >= 30 mL/min as calculated by the standard Cockcroft-Gault equation
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min obtained =< 14 days prior to registration
Obtained =< 14 days prior to registration: Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min
Creatinine clearance < 40 mL/min calculated by Cockcroft-Gault equation.
creatinine clearance < 30 ml /min based on the Cockcroft Gault equation;
Cockcroft-Gault equation: creatinine clearance = (140 - age in years) x (wt in kg)) x 1.23) / (serum creatinine in micromol/l) [For women multiply the result of calculation by 0.85].
Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of >= 51 mL/min within 28 days prior to administration of study treatment.
Within 28 days prior to administration of study treatment: Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of ? 51 mL/min
Creatinine clearance ? 40 mL/min/1.73m^2\r\n* Using 24-hour creatinine clearance or modified Cockcroft-Gault equation
Adequate renal function, defined as an estimated creatinine clearance ?30 mL/min using the Cockcroft-Gault equation
Estimated creatinine clearance (CrCL) using the Cockcroft-Gault equation >= 50 mL/min
RENAL COHORT: Laboratory values as follows within 4 days before the first dose of daratumumab: serum creatinine clearance (CrCl) ? 20 mL/min; dialysis patients will be excluded; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
BLADDER: Clinical laboratory values at screening: serum creatinine clearance (CrCl) ? 20 mL/min; dialysis patients will be excluded; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Within 7 days before the first dose of cabozantinib: Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 40 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Creatinine clearance of >= 40 mL/min, estimated or calculated using the Cockcroft-Gault equation.
Estimated creatinine clearance > 50 mL/min by Cockcroft-Gault equation
Serum creatinine =< 1.5 x upper limit of normal (ULN) or creatinine clearance > 30 mL/min based on the Cockroft-Gault equation
Creatinine clearance estimated using the Cockcroft-Gault equation of >= 51 mL/min.
Creatinine (Cr) Clearance >= 25 mL/min (per Cockcroft-Gault equation).
Creatinine clearance >= 50 ml/mm (can be calculated utilizing the Cockcroft & Gault equation)
Calculated creatinine clearance of >= 30 mL/min according to Cockcroft-Gault equation
Calculated creatinine clearance according to the Cockcroft and Gault equation >= 50 mL/min
Subject has adequate renal function: serum creatinine ? 2.0 mg/dL and estimated creatinine clearance of ? 30 mL/min by the Cockcroft-Gault equation
Measured within 28 days prior to administration of study treatment: Creatinine clearance estimated using the Cockcroft-Gault equation of >= 51 mL/min
Obtained =< 7 days prior to registration: Creatinine clearance >= 30 mL/min (as determined by Cockcroft-Gault equation)
Creatinine ?1.5 mg/dL OR estimated creatinine clearance ?60 mL/min calculated using Cockcroft-Gault equation
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Creatinine clearance >= 60 mL/min by the Cockcroft-Gault equation
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min
Creatinine clearance >= 60 mL/min, as calculated by Cockcroft-Gault equation
Creatinine clearance (CrCl) >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Part B: Renal function, as follows: creatinine clearance estimate ? 15 mL/min and <60 mL/min by cockroft gault equation adjusted for body weight
Creatinine =< 1.5 upper limit of normal (ULN) AND creatinine clearance (CrCl) > 50 mL/min by Cockcroft-Gault equation
Creatinine level < 1.0 x ULN or creatinine clearance ? 60 mL/min/1.73 m^2 for patients with creatinine levels above or below the institutional normal (as determined by Cockcroft-Gault equation). For patients with a Body Mass Index (BMI) > 30 kg/m^2, lean body weight should be used to calculate the GFR.
Serum creatinine ? ULN (with value applied to Cockcroft-Gault equation) or 24 hour clearance ? 50mL/min.
Have a calculated serum creatinine clearance greater than or equal to 45 mL/min using the Cockcroft-Gault equation
Estimated creatinine clearance (CrCl) of > 30 mL/min, as calculated by the Cockcroft-Gault equation unless disease related
Calculated creatinine clearance (eGFR) < 60 ml/min; EGFR values can be determined by either MDRD or Cockcroft-Gault equation based on the investigator’s discretion
Have a calculated creatinine clearance (Cockroft-Gault equation) > 50 mL/min
Calculated creatinine clearance (CrCl) >= 40 mL/min (based upon the Cockcroft-Gault equation)
Creatinine must be < 1.5 ULN or creatinine clearance must be > 50 mL/min (calculated by Cockcroft and Gault equation)
Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault equation for adult patients 18 to 70 years old based on ideal body weight, and the Schwartz equation for pediatric patients 6 months to 17 years old
Calculated creatinine clearance >= 30 mL/min using the Cockcroft-Gault equation
Renal function: serum creatinine ? 2.0 mg/dL and estimated creatinine clearance of ? 45 mL/min by the Cockcroft-Gault equation
Calculated creatinine clearance >= 50 mL/min using the Cockcroft-Gault equation
Creatinine ?1.5 x ULN or creatinine clearance >60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (as determined by Cockcroft-Gault equation).
Creatinine >1.5 x ULN concurrent with creatinine clearance <50 mL/min (measured or calculated by Cockcroft and Gault equation); confirmation of creatinine clearance is only required when creatinine is >1.5 x ULN
Patients must have creatinine clearance estimated using the Cockcroft-Gault equation of >= 51 mL/min.
Creatinine =< 1.5 institutional ULN or a calculated creatinine clearance >= 50 mL/min using the Cockcroft Gault equation
Serum creatinine within normal institutional limits or estimated creatinine clearance >= 60 mL/min/1.73 m^2 by the Cockcroft-Gault equation
Creatinine clearance >= 30 ml/min (as estimated by Cockcroft Gault equation)
Estimated creatinine clearance by Cockcroft-Gault equation > 30 mL/min
Estimated creatinine clearance by Cockcroft-Gault equation > 30 mL/min
Creatinine clearance (CLcr) < 30 ml/min (estimated creatinine clearance by the Cockcroft-Gault (C-G) equation) .
creatinine clearance >60 mL/min/ per Cockcroft-Gault equation for patients with creatinine levels above institutional normal.
Within one week of study entry: Creatinine clearance >= 30 ml/min (as estimated by Cockroft Gault equation)
Serum creatinine =< 1.5 X ULN or creatinine clearance >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Serum creatinine =< 1.5 mg/dl OR creatinine clearance >= 30 ml/min (as estimated by Cockroft Gault equation)
Calculated creatinine clearance (using Cockcroft-Gault equation) >= 30 mL/min (obtained =< 14 days prior to registration)
Creatine clearance < 55 mL/min, calculated using ideal body weight (IBW) using Cockcroft-Gault equation
Creatinine clearance of ? 60 mL/min as estimated by the Cockcroft-Gault equation
Inadequate renal function at screening as demonstrated by creatinine clearance < 40 mL/min calculated by Cockcroft-Gault equation.
Serum creatinine < 1.8 mg/dL or creatinine clearance greater or equal than 40 cc/min as defined by the Cockcroft-Gault equation
Creatinine ? 1.5× ULN; or, if serum creatinine > 1.5 × ULN, a measured creatinine clearance must be >60mL/min/1.73m2 as calculated by the Cockcroft and Gault equation for patient to be eligible.
Calculated creatinine clearance greater than 50 ml/min; using the Cockcroft-Gault equation
Creatinine =< 1.5 mg/dL or calculated creatinine clearance (CrCL) >= 50 mL/min using the Cockroft Gault equation
Serum creatinine =< 1.5 x ULN or creatinine clearance (CrCl) >= 50 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Serum creatinine =< 1.5 mg/dl and calculated creatinine clearance >= 50 mL/min (using the Cockcroft-Gault equation)
Serum creatinine =<1.5 mg/dl OR creatinine clearance >= 30 ml/min (as estimated by Cockroft Gault equation)
Creatinine clearance >= 60 mg/dL (Cockcroft-Gault equation)
Creatinine ? 1.5 × institutional ULN or Creatinine Clearance > 50 ml/min (as calculated by the Cockroft-Gault equation) within 14 days prior to randomization.
Calculated creatinine clearance < 30 ml/min according to Cockcroft-Gault equation
Serum creatinine clearance (Cockcroft-Gault equation) >= 50 mL/minute
Estimated creatinine clearance (CLcr) ? 60 mL/min as calculated using the Cockcroft-Gault equation
CLcr 15-29 mL/min as calculated using the Cockcroft-Gault equation
Serum creatinine =< 1.5 x ULN or serum creatinine > 1.5-3 x ULN if calculated creatinine clearance (CrCl) is >= 30 mL/min using the Cockroft-Gault equation
Serum creatinine =< 1.5 x ULN, or creatinine clearance (CrCl) >= 30 mL/min; for creatinine clearance estimation, the Cockcroft and Gault equation should be used
Serum creatinine ? 1.5 × upper limit of normal (ULN) or calculated creatinine clearance ? 60 mL/min using Cockcroft-Gault equation
Creatinine clearance >= 60 mL/min (1.00 mL/s) calculated by the Cockcroft-Gault equation for women
Creatinine =< 1.5 mg/dL or calculated creatinine clearance (CrCL) >= 50 mL/min using the Cockroft Gault equation
Calculated creatinine clearance (CrCl) >= 30 mL/min using the Cockroft Gault equation
Serum creatinine =< 1.5 x ULN or estimated creatinine clearance >= 60 mL/min by the Cockcroft-Gault equation
Calculated creatinine clearance* >= 60 ml/min\r\n* Using the Cockcroft-Gault equation
Renal: serum creatinine >=60 milliliter per minute (mL/min) either as estimated by the Cockcroft-Gault equation or based on urine collection (12 or 24 hours).
Creatinine clearance >= 30 mL/min as calculated by Cockcroft-Gault equation (obtained within 28 days prior to the first study treatment)
Creatinine =< 1.5 mg/dL is recommended; however, institutional norms are acceptable; creatinine within institutional limits of normal or creatinine clearance (CrCl) > 50 mL/min calculated using the Cockcroft-Gault equation
Adequate renal function defined as: a. Creatinine clearance >50 mL/min, as calculated with the modified Cockcroft Gault equation
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance >= 40 mL/min (using the Cockcroft-Gault equation)
Calculated creatinine clearance of > 50 mL/min using Cockcroft Gault equation equation or 24-hour urine sampling
Arm C: Calculated creatinine clearance(CrCl) > 50 ml/min using the Cockcroft-Gault equation
eGFR > 40 mL/min using the Cockcroft-Gault equation
Creatinine clearance >50 mL/min/1.73 m2 based on Cockcroft Gault equation.
- Serum Cr < 1.5 x ULN or estimated GFR > 60 ml/min based upon Cockroft-Gault equation
Creatinine < 1.5 x upper limit of normal (ULN) or estimated creatinine clearance >= 50 mL/min (by the Cockcroft Gault equation)
Creatinine < 1.5 x upper limit of normal (ULN) or estimated creatinine clearance >= 50 mL/min (by the Cockcroft Gault equation)
Renal dysfunction as defined as creatinine clearance < 70 mL/min by Cockcroft-Gault equation
HEALTHY VOLUNTEER: An estimated creatinine clearance of =< 80 ml/min based on the Cockcroft-Gault equation; an actual creatinine clearance, as determined by a 24 hour urine collection, may be used in place of the Cockcroft-Gault equation; subjects who have an actual or estimated creatinine clearance 70 ml/min may be enrolled at the discretion of the investigator
Estimated creatinine clearance >= 50 mL/min (by the Cockcroft Gault equation)
Serum creatinine =< 1.5 x upper limit of normal (ULN) or calculated creatinine clearance (CrCl) >= 50 mL/min as determined by the Cockcroft-Gault equation
Estimated creatinine clearance by the Cockcroft Gault equation >= 50 mL/min
- Serum Cr < 1.5 x ULN or estimated GFR > 60 ml/min based upon Cockroft-Gault equation
Renal: serum creatinine <=1.5*ULN or creatinine clearance >=60 milliliter per minute (mL/min) as estimated by the Cockcroft-Gault equation or based on urine collection (12 or 24 hours).
Estimated serum creatinine clearance of ? 60 mL/min using the Cockcroft-Gault equation.
Creatinine clearance must be greater than or equal to (>=) 60 milliliter per (mL/) minute as estimated by the Cockcroft Gault equation or based on urine collection (12 or 24 hours).
Serum creatinine =< 1.5 x ULN OR creatinine clearance >= 60 mL/min/1.73 m^2 for patients with creatinine levels above institutional normal (calculated with the Cockcroft-Gault Equation in EPIC)
Serum creatinine < 1.5 times institutional upper limit of normal OR calculated creatinine clearance (CrCl) >= 40 mL/min (based upon the Cockcroft-Gault equation)