History of severe allergic reactions to any unknown allergens or any components of the study drugs. History of severe allergic reactions to vaccines or unknown allergens Patients must not have a history of severe allergic reactions (i.e., grade 4 allergy, anaphylactic reaction from which the subject did not recover within 6 hours of institution of supportive care) to any unknown allergens or any components of the nivolumab formulations Previous history of anaphylaxis or severe allergic reaction to hsp110, gp100, other vaccines, or unknown allergens History of severe allergic reactions to any unknown allergens or any components of the study drugs. History of severe allergic reactions to any unknown allergens or any components of the study drugs History of severe allergic reactions to any unknown allergens or any components of the study drugs History of severe allergic reactions to any unknown allergens or components of the study drugs. History of severe allergic reactions to any unknown allergens or any components of the study drug formulations History of severe allergic reactions to any unknown allergens or any components of the study drugs. History of severe allergic reactions to vaccines or unknown allergens. History of severe allergic reactions to any unknown allergens or any components of the study drug formulations. No history of previous severe allergic reactions to vaccines or unknown allergens Participants who have a known severe allergic response to one or more allergens, as defined by anaphylaxis. Participants who have a known severe allergic response to one or more allergens, defined as anaphylaxis Participants who have a known severe allergic response to one or more allergens