Participants may not have received any prior treatment with therapies targeting PDL1, PD1 or CTLA4 Prior PD-1 or CTLA-4 targeted therapies are excluded Prior PD-1 or CTLA-4 targeted therapies are excluded. Prior PD-1 or CTLA-4 targeted therapies are excluded. Prior PD-1 or CTLA-4 targeted therapies are excluded. Prior PD-1 or CTLA-4 targeted therapies are excluded. Prior PD-1 or CTLA-4 targeted therapies are excluded. Prior PD-1 or CTLA-4 targeted therapies are excluded. Receipt of anti-CTLA-4 targeted therapies or other checkpoint or co-stimulatory therapy within 3 months prior to start of study treatment.