Chronic gastrointestinal illness Uncontrolled serious medical or psychiatric illness Patients with an active psychiatric or mental illness making informed consent or careful clinical follow-up unlikely are excluded Patients should have NO significant medical or psychiatric illness that would interfere with compliance and ability to tolerate treatment as outlined in the protocol Severe psychiatric illness or mental deficiency making compliance to treatment unlikely and/or informed consent impossible DONOR: Severe psychiatric illness or mental deficiency making compliance with donation unlikely and/or informed consent impossible Mental incapacitation or psychiatric illness that would preclude study participation A major psychiatric illness which would limit understanding of the proposed protocol treatment and consent process Patients with severe co-extensive comorbidities or significant psychiatric illness Any serious medical illness, other than that treated by this study, which would limit survival to less than 1 month or psychiatric illness which would limit informed consent Patients with a history of serious co-morbid illness or uncontrolled illnesses that would preclude protocol therapy. Any serious medical illness, other than treated by this study, which would limit survival to less than 1 month or psychiatric illness which would limit informed consent Patients with a mental disorder, psychiatric illness/social or concussion which would inhibit their ability to provide informed consent or prevent compliance with follow-up Patients should not have a history of significant psychiatric illness If history of depression or psychiatric illness, has to be well controlled with antidepressants and/or under psychiatrist/ psychologist care Severe psychiatric illness or mental deficiency sufficiently severe as to make compliance with the transplant treatment unlikely and informed consent impossible Significant underlying medical or psychiatric illness Have additional uncontrolled serious medical or psychiatric illness. Other serious medical illness other than that treated by this study which would limit survival to <2 years or psychiatric conditions which would prevent informed consent or compliance with treatment. Patients with serious unstable medical illness Patients must not have a serious medical or psychiatric illness which prevents informed consent or compliance with treatment Psychiatric illness which may make compliance to the clinical protocol unmanageable or which may compromise the ability of the patient to give informed consent Patients with serious unstable medical illness Significant underlying medical or psychiatric illness. Patients should not have a history of significant psychiatric illness Significant underlying medical or psychiatric illness Significant underlying medical or psychiatric illness Psychiatric illness that may affect the patient's compliance with the treatment. Subjects with uncontrolled medical or mental illness that, in the Investigator's judgement, could affect treatment tolerability or compliance. Have psychiatric or other medical illness, or any other condition that in the opinion of the investigator prevents compliance with the study procedures or ability to provide valid informed consent. Psychiatric, other medical illness or other condition that in the opinion of the principal investigator (PI) prevents compliance with study procedures or ability to provide valid informed consent. No serious medical or psychiatric illness which prevents informed consent or intensive treatment is allowed Medical or psychiatric illness which would compromise the patient's ability to tolerate treatment or limit compliance with study requirements Patients with serious unstable medical illness Psychiatric, other medical illness or other condition that in the opinion of the PI prevents compliance with study procedures or ability to provide valid informed consent Psychiatric, other medical illness or other condition that in the opinion of the PI prevents compliance with study procedures or ability to provide valid informed consent. Psychiatric, other medical illness or other condition that in the opinion of the PI prevents compliance with study procedures or ability to provide valid informed consent uncontrolled psychiatric illness; Significant psychiatric illness If the patient has co-morbid medical illness, life expectancy attributed to the comorbid illness must be greater than 6 months Significant or acute medical illness Evidence of significant medical illness, abnormal laboratory finding or psychiatric illness/social situations that would, in the investigator’s judgment, makes the patient inappropriate for this study Other uncontrolled, concurrent illness that would preclude study participation; or, psychiatric illness or social challenges that would entail unreasonable risk or preclude informed consent or compliance with study procedures Subjects who have a history of significant psychiatric illness Have no active cardiac, neurologic, or psychiatric illness, and No significant co-morbid medical or psychiatric illness that would significantly compromise the patient’s clinical care and chances of survival Patients must not have a severe psychiatric illness, including major depression or any previous suicide attempts Hospitalized for psychiatric illness within the past two years Patient has a serious medical or psychiatric illness which prevents informed consent or adherence with treatment Psychiatric illness that may make compliance to the clinical protocol unmanageable or may compromise the ability of the patient to give informed consent Severe concomitant medical or psychiatric illness Any debilitating medical or psychiatric illness that would preclude ability to give informed consent or receive optimal treatment and follow-up DONOR: Untreatable/unstable psychiatric illness Patients with serious unstable medical illness No serious medical or psychiatric illness which prevents informed consent or intensive treatment Serious intercurrent medical or psychiatric illness Patients with serious unstable medical illness Patients should have no significant psychiatric illness or medical illness that would preclude the ability to comply with the protocol Concurrent serious medical illness that could potentially interfere with protocol compliance (such medical illness will not include hepatitis or cirrhosis, as the degree of liver impairment caused by these diseases are covered by other exclusion criteria). Patients should have no significant psychiatric illness or medical illness that would preclude the ability to comply with the protocol Any serious medical or psychiatric illness Comorbid systemic illness or psychiatric illness that could interfere with study completion Any serious medical or psychiatric illness History of clinically significant psychiatric illness that would prevent the patient from providing a valid ICF and complying with protocol requirements Have additional uncontrolled serious medical or psychiatric illness. Severe concomitant medical or psychiatric illness Must be cognitively intact and free of serious psychiatric illness (as determined by study recruiter at intake) Significant psychiatric disturbance verified by medical record sufficient to preclude completion of the assessment measures, interview or informed consent (i.e. acute psychiatric symptoms which require individual treatment) Major psychiatric illness or comorbid conditions prohibiting compliance with study procedures as determined by the treating oncologist Diagnosis of major mental illness on the medical record (verified by the recruiter) Patients with any medical illness or concurrent psychiatric illness which, in the investigators’ opinion, cannot be adequately controlled with appropriate therapy Immunosuppression as a result of underlying illness or treatment; Major psychiatric illness or co-morbid conditions prohibiting compliance with study procedures History of hospitalization for psychiatric illness Have a diagnosis of psychiatric illness or other major illness in addition to PCa, such as other cancers, uncontrolled hypertension, lung disease, liver disease or heart disease Serious underlying medical comorbidity such as uncontrolled hypertension, cardiovascular disease, pulmonary disease, psychiatric illness, or any other condition for which the patient is not approved for exercise by their physician Self-report of hospitalization for psychiatric illness within the last two years Unstable self-reported medical or psychiatric illness (Axis I – current or within the last 5 years) that would make it unsafe or impossible to adhere to the study protocol No history of prior inpatient psychiatric treatment for severe mental illness within 1 year (e.g., psychosis) History of prior inpatient psychiatric treatment for severe mental illness within the past year (e.g., psychosis), DONOR: Severe psychiatric illness. Mental deficiency sufficiently severe as to make compliance with the donation procedure unlikely, and making informed consent impossible Participants who exhibit confusion, disorientation, or have a history of major psychiatric illness which may impair their understanding of the informed consent Severe psychiatric illness Severe psychiatric illness No uncontrolled serious medical or psychiatric illness Have been hospitalized for treatment of a major psychiatric illness within the last five years Poorly controlled hypertension, DM or other serious medical/psychiatric illness