Histological confirmation of melanoma will be required by previous biopsy or cytology. Histological confirmation of clear cell renal cancer Histological Diagnosis Histological confirmation of adenocarcinoma of the prostate within 6 months of study enrollment Histological confirmation of follicular lymphoma grades I, II diagnosed within 12 months (365 days) prior to registration; NOTE: the day of biopsy should be used as day 1 of diagnosis for this calculation At least one volumetrically measurable and >= 1 cc NF2-related VS (histological confirmation not required) Histological confirmation of ER negative breast carcinoma (defined as less than 10%), stage I, II, or III Patients with a histological diagnosis of lymphomas and/or leukemias Confirmation of diagnosis Evidence of active disease (histological confirmation of reactivation or progression is not required) Have histological confirmation of breast cancer with recurrent and/or metastatic lesions via investigational site which has failed prior therapy. Histological confirmation of mycosis fungoides as confirmed by the Mayo Clinic Arizona Dermatopathology Department Histological confirmation of stage IIIB, IIIC, IVM1a, IVM1b, or IVM1c that is not suitable for surgical resection Histological confirmation of breast cancer Have histological confirmation of breast cancer with recurrent and/or metastatic lesions via investigational site. Histological confirmation of malignancy (primary tumor) Histological confirmation of malignant carcinoma/sarcoma (any site) with metastasis to lung; histologic confirmation of the lung metastasis is not required providing there has been pathologic confirmation of malignancy Histological confirmation of cholangiocarcinoma Has histological confirmation of breast carcinoma. Have histologically or cytologically documented HCC (documentation of original biopsy for diagnosis is acceptable if tumor tissue is unavailable) or clinical diagnosis by American Association for the Study of Liver Diseases (AASLD) criteria in cirrhotic subjects is required; for subjects without cirrhosis histological confirmation is mandatory Histological confirmation of GIST Patients must have histological confirmation of breast carcinoma Have histological confirmation of HER2 positive breast cancer Histologic confirmation of malignancy Patients must have histological confirmation of metastatic urothelial carcinoma; patients must have sufficient tumor tissues for future MTAP testing and research; histological variants such as glandular, squamous, sarcomatoid, micropapillary, plasmacytoid, and small cell changes will not be allowed for this trial unless these tumors are MTAP-deficient Histologic confirmation is not required for this if the patient has neurofibromatosis type 1 (NF-1) with magnetic resonance imaging (MRI) findings consistent with optic pathway glioma or juvenile pilocytic astrocytoma (JPA); any other tumors will need histological confirmation, either at the time of diagnosis or at the time of recurrence; the histological diagnosis includes World Health Organization (WHO) grade I JPA Histological documentation of mCRC Histological confirmation of pheochromocytoma (PH)/paraganglioma (PG) Patients must have histological confirmation of metastatic cancer with at least one metastatic or primary lesion in the liver, lung, or adrenal gland Histological confirmation of SCLC. Histological confirmation of relapsed/refractory CD20 positive diffuse large B-cell lymphoma; network sites must submit slides to Roswell Park for central review and confirmation Confirmation of diagnosis Histological diagnostic material available for review. All patients must have histological proof of malignant cancer, which is metastatic; histological proof may be obtained from the primary tumor or another metastatic site; however, cytology alone is not an acceptable method of diagnosis Histological diagnosis of cholangiocarcinoma, hepatocholangiocarcinoma, fibrolamellar carcinoma and hepatoblastoma Confirmation of diagnosis: Patients with histological confirmation of locally advanced or metastatic NSCLC Patients must have histological confirmation of a cutaneous T-cell lymphoma (CTCL) of any histology; confirmation of histological diagnosis must be completed prior to enrollment by the lead site (Northwestern)\r\n* Patients will be stratified by mycosis fungoides (MF) and Sezary syndrome (SS) (report diagnostic or consistent with MF/SS), stage IA-IVB according to TNM blood (TNMB) classification versus other CTCL histologies Histological confirmation of relapsed or refractory AML after prior anti-leukemic therapy by WHO Classification Histological confirmation of adenocarcinoma of the breast Patients have histological confirmation of invasive breast carcinoma other histological type of lymphoma Histological confirmation of breast carcinoma Histological confirmation of glioblastoma histological confirmation of transformation, or Histological confirmation of thymoma Histological confirmation of CTCL; a documented verifiable biopsy report is required Patients must have histological confirmation of a brain tumor at diagnosis or relapse for all tumors Histological or cytologic diagnosis of squamous cell cancer Patients have histological confirmation of breast carcinoma Patients with histological or cytologically documented hepatocellular carcinoma (HCC) (documentation of original biopsy for diagnosis is acceptable if tumor tissue is unavailable) or clinical diagnosis by American Association for the Study of Liver Diseases (AASLD) criteria in cirrhotic subjects is required; for subjects without cirrhosis histological confirmation is mandatory Subjects must have a histological diagnosis of cancer Histological confirmation of malignancy (primary or metastatic tumor) Confirmation of: Histological confirmed diagnosis of relapsed intracranial GB Subjects with histological confirmation of RCC Histological confirmation of malignancy (primary or metastatic tumor) Histological confirmation of breast carcinoma; pathologic evidence of dermal lymphatic invasion should be noted but not required Prior surgery for a low grade tumor is allowed, provided histological confirmation of anaplastic tumor is present at the time of progression (2. continued) Patients with prior therapy that included interstitial brachytherapy, Gliadel wafers or stereotactic radiosurgical procedures must have confirmation of true progressive disease rather than radiation necrosis. Such confirmation may be using advanced imaging studies (e.g. PET scans, diffusion-perfusion MRI, SPECT etc) or if available, surgical sampling and histological confirmation (surgery is not required). Histological diagnosis of GIST. Histologic confirmation not required if other diagnostic criteria are met; Histological or cytologic confirmation of unresectable or metastatic cholangiocarcinoma (intrahepatic, hilar, extrahepatic bile duct) Histological diagnosis of cancer No histological confirmation of breast cancer Histological diagnosis of high-grade osteosarcoma All patients with a histological diagnosis of cancer Histological confirmation of breast cancer Histological diagnosis of NET Histological confirmation of prostate cancer Histological confirmation of prostate cancer Histological confirmation of prostate cancer