Urine protein: creatinine (UPC) ratio < 1 or urine dipstick for proteinuria =< 2+ (note: if the UPC ratio is >= 1.0 then a 24-hour urine collection should be performed and this must demonstrate =< 1g of protein in 24 hours)
Within 2 weeks prior to registration: Screening urine dipstick must equal 0 or “trace”; if urine dipstick results are >= 1+, or if dipstick was not performed, calculation of urine protein creatinine (UPC) is required and patients must have a UPC ratio =< 1 to participate in the study
Urine protein creatinine (UPC) =< 1; if UPC >= 1, then a 24-hour urine protein must be assessed; eligible patients must have a 24-hour urine protein value < 1 g/L
Within 14 days prior to registration: Urine protein creatinine (UPC) ratio must be < 1.0 gm; if UPC ratio >= 1, collection of 24-hour urine measurement of urine protein is recommended (24-hour urine protein level must be < 1000 mg for patient enrollment); UPC ratio of spot urine is an estimation of the 24-hour urine protein excretion – a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm
Urine Protein to Creatinine Ratio (UPC) < 1
Urine protein <500 mg or urine protein: creatinine ratio (UPC) <1.0; and
Within 28 days prior to administration of study treatment: Urine protein: creatinine ratio (UPC) of =< 1
Urine protein to creatinine (UPC) ratio =< 1
(Bevacizumab-related exclusion) Proteinuria as demonstrated by a urine protein:creatinine (UPC) ratio >= 1.0 at screening
Urine protein creatinine (UPC) ratio of < 1
Proteinuria as demonstrated by a urine protein:creatinine (UPC) ratio >= 1.0 at screening
Urine protein screened by urine analysis for urine protein creatinine (UPC) ratio; for UPC ratio > 0.5, 24-hour urine protein must be obtained and must be < 1000 mg
Urine protein creatinine (UPC) < 1 or, if UPC >= 1, 24-hour urine protein < 1 g; use of urine dipstick for renal function assessment is not acceptable
Urine protein to creatinine ratio (UPC) < 1; if UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Proteinuria at screening as demonstrated by either urine protein: urine protein creatinine (UPC) ratio >= 1.0 or 24hr collection > 1g/24hr at screening
Urine protein to creatinine ratio (UPC) < 1; NOTE: if UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein:creatinine ratio (UPC) =< 45 mg/mmol; ONLY APPLICABLE for patients with NF2 mutation (GSK2256098)
Urine protein: creatinine ratio (UPC) of =< 1; UPC is the preferred test
Urine protein: creatinine ratio urine protein creatinine (UPC) of =< 1 OR less than or equal to 2+ proteinuria on two consecutive dipsticks taken no less than 1 week apart; UPC is the preferred test; patients with 2+ proteinuria on dipstick must also have a 24-hour urine collection demonstrating protein of =< 500 mg over 24 hours
Urine protein/creatinine ratio (UPCR) =< 1; if urine/protein creatinine (UPC) >= 1, then a 24-hour urine protein must be assessed; eligible patients must have a 24-hour urine protein value < 1 g/L
Urine protein should be screened by dipstick analysis; if protein >= 2+ on dipstick, then urine protein creatinine (UPC) ratio should be calculated; if UPC ratio > 0.5, 24-hour urine protein should be obtained and the level should be < 1000 mg/24 hours for patient enrollment
Urine protein to urine creatinine ratio (UPC) should be less than 1; if greater than 1, then 24 hour urine protein must be less than 1 g for patient to be eligible
Subjects must have a urine protein/creatinine (UPC) ratio < 1; if UPC >= 1, then a 24-hour urine total protein must be obtained; subjects must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Urine protein creatinine (UPC) < 1 (in like units) or, if UPC >= 1, 24-hour urine protein < 1 g; use of urine dipstick for renal function assessment is not acceptable
Urine protein creatinine (UPC) ratio < 1 OR urine protein =< 1+
Patients are excluded if they have proteinuria at screening as demonstrated by either:\r\n* Urine dipstick for proteinuria >= 2+ (patients discovered to have >= 2+ proteinuria on dipstick urinalysis at baseline should undergo a 24 hour urine collection and must demonstrate =< 1 g of protein in 24 hours to be eligible) OR\r\n* Urine protein: creatinine (UPC) ratio >= 1.0 at screening; for UPC ratio > 1, a 24 hour urine protein should be obtained and the level should be < 1000mg; NOTE: urine protein should be screened by urine analysis for UPC ratio; a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 g
Urine protein/creatinine (UPC) ratio < 1.0 within 14 days prior to registration; if the UPC ratio is >= 1.0 then the patients should undergo a 24-hour urine collection and must demonstrate =< 1g of protein in 24 hours to be eligible)
Grade 2 or higher proteinuria (2+ or higher protein on urinalysis or urine protein:creatinine (UPC) ratio >= 1.0; if both tests are performed, UPC should be used to evaluate eligibility) or hematuria
Urine protein-to-creatinine (UPC) ratio =< 2 mg/mg or 24-hour urine protein < 2 g
Urine protein creatinine (UPC) ratio must be < 1.0 gm
Urine protein to creatinine ratio (UPC) < 1 (tested within 14 days prior to registration)\r\n* If UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
24-hour urine protein, if required < 1 g (tested within 14 days prior to registration)\r\n* If UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Urine protein to creatinine ratio < 1, or, 24-hour urine protein < 1 g; if urine protein to creatinine (UPC) >= 1, then a 24-hour urine protein must be assessed; patients must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Urine protein to creatinine ratio (UPC) < 1\r\n* Or, 24-hour urine protein < 1 g\r\n* If UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein =< 1+ OR urine protein to creatinine (UPC) ratio =< 1; if UPC ratio is > 1 on urinalysis, then 24-hour urine collection for protein must be obtained and level must be < 1,000 mg for patient enrollment
Urine protein should be screened by urine analysis for urine protein creatinine (UPC) ratio; for UPC ratio > 0.5, 24-hour urine protein should be obtained and the level should be < 1000 mg for patient enrollment; NOTE: UPC ratio of spot urine is an estimation of the 24-urine protein excretion; a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm
Urine protein: creatinine (UPC) ratio < 1.0 within 14 days prior to registration OR urine dipstick for proteinuria =< 2 positive (+) (patients discovered to have > 2+ proteinuria on dipstick urinalysis at baseline must have a UPC ratio done that is < 1.0 to be eligible; if the UPC ratio is >= 1.0 then the patients should undergo a 24-hour urine collection and must demonstrate =< 1g of protein in 24 hours to be eligible)\r\n* Note: UPC ratio of spot urine is an estimation of the 24-hour urine protein excretion; a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm
Urine protein to creatinine ratio (UPC) < 1; if UPC >= 1, then a 24-hour urine protein must be assessed; patients must have a 24-hour urine protein value < 1 g to be eligible
Urine Protein Creatinine (UPC) ratio < 1.0 or 24 hour urine protein ratio < 1000 mg
Urine protein to creatinine ratio < 1; or, 24-hour urine protein < 1 g; if urine protein creatinine ratio (UPC) >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible; use of urine dipstick for renal function assessment is not acceptable
Urine protein to creatinine ratio (UPC) < 1; if UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein to creatinine ratio (UPC) =< 1; a UPC is required only if the urine protein is > 100; if UPC >1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein to creatinine ratio (UPC) < 1
Urine protein to creatinine (UPC) ratio of < 1 assessed in a random or spot urine sample; if UPC >= 1, then a 24-hour urine protein must be assessed; patients must have a 24-hour urine protein value < 1 gram to be eligible
Proteinuria as demonstrated by a urine protein: creatinine (UPC) ratio >= 1.0 at screening
Serum creatinine =< 1.5 x ULN or calculated creatinine clearance (CrCl) >= 40 cc/min and random urine protein:creatinine ratio (UPC) < 1 or 24-hour (hr) urine protein < 1 g, within 14 days of registration
Urine protein to creatinine ratio (UPC) < 1 (note, if >= 1, then a 24-hour urine protein must be assessed: if 24-hour urine protein > 1 g, patient ineligible)
Urine protein to urine creatinine ratio (UPC) < 1.0; if UPC >= 1 then a 24 hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
EXPANSION COHORT ONLY: Urine protein to urine creatinine ratio (UPC) < 1.0; if UPC >= 1 then a 24 hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein/creatinine (UPC) ratio =< 1.0 unless the patient has a neobladder
UPC ratio < 1.0 at screening or 24 hours urine protein < 1 gm (Appendix D)
Urine protein creatinine (UPC) ratio < 1; note: urine protein must be screened by urine analysis for UPC ratio; for UPC ratio >= 1.0, 24-hour urine protein must be obtained and the level should be < 1,000 mg for registration
If baseline urine protein creatinine (UPC) >= 1, a 24-hour urine protein must be assessed; patients must have a 24-hour urine protein value < grade 3 (> 3.5 g/24 hours) to be eligible
Proteinuria, as demonstrated by a 24-hour protein of >= 2000 mg; urine protein will be screened by urine protein-creatinine ratio (UPC); for UPC ratio > 1.0, a 24-hour urine protein will need to be obtained and the level should be < 2000 mg for patient enrollment
Urine protein to creatinine (UPC) ratio < 1; if UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Proteinuria as defined by positive urine dipstick for protein OR urine protein/creatinine (UPC) ratio >= 1.0; if these criteria are not met, the patient must have a 24 hour urine collection that demonstrates < 1 gm protein over 24 hours
Urine to protein to creatinine (UPC) ratio < 1; if UPC > 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1 g to be eligible
Urine protein to creatinine (UPC) ratio < 0.5 or if >= 0.5, 24-hour urine protein must be < 1000 mg
Urine protein: creatinine (UPC) ratio < 1.0 within 14 days prior to registration OR urine dipstick for proteinuria ? 2+ (patients discovered to have > 2+ proteinuria on dipstick urinalysis at baseline must have a UPC ratio done that is <1.0 to be eligible. If the UPC ratio is ? 1.0 then the patients should undergo a 24-hour urine collection and must demonstrate ? 1g of protein in 24 hours to be eligible). *Note: UPC ratio of spot urine is an estimation of the 24-hour urine protein excretion; a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm. UPC ratio is calculated using one of the following formulas:
Proteinuria as demonstrated by a urine protein creatinine (UPC) ratio >= 1.0 at screening
Urine protein to creatinine ratio (UPC) < 1 (evaluated within 28 days of randomization); if UPC >= 1, then a 24-hour urine protein must be assessed; subjects must have a 24-hour urine protein value < 1g to be eligible
Urine protein should be screened by dipstick analysis; if protein >= 2+ on dipstick, then urine protein creatinine (UPC) ratio should be calculated; if UPC ratio > 1, 24-hour urine protein should be obtained and the level should be < 1000 mg/24 hours for patient enrollment; Note: UPC ratio of spot urine is an estimation of the 24 hour urine protein excretion- a UPC ratio of 1 is roughly equivalent to a 24-hour urine protein of 1 gm