AST/ALT =< 3 x upper limit of normal (ULN)
AST =< 8 x upper limit of normal (ULN)
INCLUSION CRITERIA FOR SECOND-LINE THERAPY: For patients with known hepatic metastases, AST and ALT =< 5 X the upper normal limit of institution's normal range
INCLUSION CRITERIA FOR THIRD-LINE THERAPY: AST and ALT =< 3 X the upper normal limit of institution's normal range
INCLUSION CRITERIA FOR THIRD-LINE THERAPY: For patients with known hepatic metastases, AST and ALT =< 5 X the upper normal limit of institution's normal range
AST and ALT ? upper limit of normal
Hepatic: direct bilirubin ? 3 x upper limit of normal, or AST/ALT ? 5 x upper limit of normal
AST ? 5 x upper limit of normal
AST and ALT ? 5 x the upper limit of normal
AST and ALT ? 3.0 X the upper normal limit of institution's normal range
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x the upper normal limit of institution's normal range, at the time of enrollment; for subjects with liver metastases, AST and ALT =< 5 x the upper normal limit of institution's normal range are acceptable as long as there is no persistent nausea, vomiting, right upper quadrant pain or tenderness, fever, rash, or eosinophilia
ALT < 2 x upper limit of normal
DONOR: ALT < 2 x upper limit of normal
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 x the upper normal limit of institution's normal range; for subjects with liver metastases, AST and ALT < 5 x the upper normal limit of institution's normal range are acceptable as long as there is no persistent nausea, vomiting, right upper quadrant pain or tenderness, fever, rash, or eosinophilia
AST and ALT =< 2 x institutional upper limit of normal
AST or ALT >= 3 x ULN (upper limit of normal)
ADDITIONAL CRITERIA FOR STUDY CONTINUATION: AST and ALT =< 2 X upper level of normal
AST and ALT <5x upper limit of normal
Patients who test positive for hepatitis C (HepC) antibodies (Ab) are eligible provided all of the following criteria are met: bilirubin =< 2 x upper limit of normal; ALT/AST =< 3 x upper limit of normal; and clinical evaluation to rule out cirrhosis
RANDOMIZED PHASE II (ARMS K AND L): AST/ALT =< 2.5 x upper limit of normal (ULN), obtained within 2 weeks prior to registration
Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) must be =< 3 X normal\r\n* If AST and ALT are > 3 < 5 x upper limit of normal (ULN), patient may be eligible if:\r\n** Liver biopsy performed within 60 days of hematopoietic cell transplantation (HCT) excludes active cirrhosis grade greater than 2/4 and bridging fibrosis\r\n** No clinically evident ascites\r\n** Patient with hepatitis B or C are excluded if AST or ALT > 3 x upper limit (UL)
AST & ALT ? 5 x the upper limit normal
AST, ALT, and total bilirubin ? 3x upper limit of normal;
DONORS: ALT < 2 x upper limit of normal
Subjects must have normal organ and marrow function as defined below:\n\n               1. Absolute neutrophil count ? 1500/cmm\n\n               2. Platelets ? 100,000/cmm\n\n               3. Total bilirubinwithin normal limits of the institution\n\n               4. AST/ALT ? 2.5 X institutional upper limit of normal (ULN) or ? 5 X institutional\n                  upper limit of normal (ULN) in the presence of liver metastases\n\n               5. Creatinine ? 1.5 X institutional upper limit of normal (ULN)
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 × the upper normal limit of institution's normal range; for subjects with liver metastases, AST and ALT < 5 × the upper normal limit of institution's normal range AS LONG AS THERE IS NO persistent nausea, vomiting, right upper quadrant pain or tenderness, fever, rash, or eosinophilia
DONOR: ALT < 2 x upper limit of normal
AST and ALT > 2 x upper limit of normal
AST and ALT >= 2 x upper limit of normal
AST/ALT =< 3 X upper limit of normal (ULN)
AST or ALT ? 3 x the institutional upper limit of normal
ALT and AST< 5 X upper limit of normal
AST/ALT > 3 x upper limit of normal
AST/ALT ? 3X ULN (upper limit of normal)
AST/ALT =< 2 x upper limit of normal (ULN)
AST =< 5 x upper limit of normal
Serum AST and ALT ? 2.5 x Institutional upper limit of normal (ULN)
DONOR: ALT < 2 x upper limit of normal
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 × the upper normal limit of institution's normal range; for subjects with liver metastases, AST and ALT < 5 × the upper normal limit of institution's normal range are acceptable AS LONG AS THERE IS NO persistent nausea, vomiting, right upper quadrant pain or tenderness, fever, rash, or eosinophilia; the combination of 5-FU and oxaliplatin is known to be safe to be administered in patients with such abnormal liver function tests
AST =< 2 x upper limit of normal
AST or ALT > 2 x upper limit of normal
AST/ALT ? 5 X upper limit of normal
DONOR: ALT < 2 x upper limit of normal
AST and ALT ?3 x upper limit of normal
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 3.0 X the upper normal limit of institution's normal range; for subjects with liver metastases, AST and ALT < 5 X the upper normal limit of institution's normal range AS LONG AS THERE IS NO persistent nausea, vomiting, right upper quadrant pain or tenderness, fever, rash, or eosinophilia
Hepatic function: AST and ALT ? 2.5 × the upper normal limit of institution's normal range. For subjects with liver metastases, AST and ALT ? 5 × the upper normal limit of institution's normal range;
AST and ALT </= 3x the upper limit of normal
ALT < 2.5 X institutional upper limit of normal
ALT and AST > 2.5 X upper limit of normal
AST/ALT =< 2.5 x upper limit of normal (ULN)
AST and ALT <10x upper limit of normal
AST, ALT ? 2.5 x upper limit of normal