Karnofsky performance status (KPS) >= 60% Karnofsky Performance Status (KPS) rating of >/=70 at baseline; Patients must have a Karnofsky performance status (KPS) >= 60 Must have an ECOG performance status of 0 - 2, or KPS ? 60. Karnofsky performance status (KPS) >= 70 Patients must have a KPS performance status of >= 60 Karnofsky Performance Status (KPS) of ?70 Karnofsky performance status (KPS) of at least 60%. Karnofsky performance status (KPS) ? 70 Karnofsky performance status (KPS) >= 70% Patients must have a Karnofsky performance status (KPS) >= 60 Patient has a Karnofsky performance status (KPS) ? 70. Karnofsky performance status (KPS) >= 70 within two weeks of enrollment Karnofsky performance status (KPS) >= 50 Karnofsky performance status (KPS) of greater than or equal to 70 Karnofsky performance status (KPS) ? 60 Karnofsky performance status (KPS) >= 70% Karnofsky score >= 70% (inpatient leukemia service transfers without discharge are acceptable provided patient has equivalent Karnofsky performance status [KPS] as if were outpatient). Karnofsky performance status (KPS) >= 60% Must have a Karnofsky Performance Status (KPS) >= 70 at assessment <= 14 days prior to randomization (N/A to the sub-study). Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) < 60 Karnofsky performance status (KPS) < 70 Karnofsky performance score (KPS) >= 70% ECOG performance status of 0 or 1 (51), or KPS of 100% to 80% (52) Karnofsky performance status (KPS) >= 80 Karnofsky performance status (KPS) of at least 70% Karnofsky performance status (KPS) of >= 80% on the modified KPS tool Patients must have a Karnofsky performance score (KPS) > 60. Have a Karnofsky performance score (KPS) >= 60 Karnofsky performance status (KPS) >= 70 Have a Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) performance status of 60% or greater Karnofsky performance score (KPS) >= 70% Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 70 Patients must exhibit a Karnofsky performance status (KPS) >= 70 Karnofsky Performance Status (KPS) ? 60%. Patients must have Karnofsky Performance Status (KPS) > 60% (i.e., 70, 80, 90 or 100). Karnofsky performance status (KPS) of at least 60% Patients should have a Karnofsky performance status (KPS) greater than or equal to 70% Karnofsky performance status (KPS) >= 70 Have a performance status of >= 60 on the Karnofsky performance status (KPS) Karnofsky Performance Status (KPS) ? 70% Karnofsky Performance Status (KPS) >= 70 Karnofsky performance status (KPS) >= 90% patients older than 70 years, KPS >= 80% patients younger than 70 years Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) < 60% Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 60% Karnofsky performance status (KPS) >= 60% Karnofsky performance status (KPS) of >= 70 Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) of >= 70% Karnofsky performance status score (KPS) of >= 60 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) >= 60 Patient with Karnofsky performance status (KPS) equal to or greater than 40 Patients with Karnofsky performance status (KPS) less than 40 Karnofsky performance status (KPS) score >= 70 Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) of greater than or equal to 60 Performance status evaluated by Eastern Cooperative Oncology Group (ECOG) or Karnofsky performance scales (KPS) patients must have a score of 0-II (ECOG) or >= 70% (KPS) Karnofsky Performance Status (KPS) <50% Karnofsky performance score (KPS) ? 70% Karnofsky Performance Status (KPS) of >/=70%. Karnofsky performance status (KPS) >= 80% within 7 days prior to registration for protocol therapy Participant has a Karnofsky performance status (KPS) of 70 or higher. Karnofsky performance score (KPS) >= 70 Karnofsky performance status (KPS) performance status of 60% or greater Participants must have a Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 70% RPA class III (Karnofsky performance status [KPS] < 70%) Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 80 Karnofsky performance status equal to 50 or higher, with the following exception\r\n* Patients with Karnofsky performance status (KPS) 30 to 50 are eligible if the reason for the poor performance status is neurologic deficit from primary central nervous system (CNS) lymphoma; (patients with KPS 30 to 50 due to reasons other than primary CNS lymphoma are ineligible; patients with KPS under 30 for any reason are ineligible) Karnofsky performance status of 70% or greater; lower Karnofsky performance status (KPS) down to 50% may be acceptable if the restriction of activity is solely due to intractable pain from myeloma lesions Karnofsky performance status (KPS) >=70 ECOG performance score >= 3 (Karnofsky performance status [KPS] < 50%) Karnofsky Performance Status (KPS) of at least 70% for Cohort 1, 2, and 3; KPS of 50-60% for Cohort 4 Karnofsky performance status (KPS) >= 70% Karnofsky Performance Score (KPS) ? 70% Has Karnofsky Performance Status (KPS) ?70%, as assessed within 10 days prior to treatment allocation. Has Karnofsky performance status (KPS) ? 70% as assessed within 10 days prior to randomization. Karnofsky performance status (KPS) >= 70 Karnofsky Performance Status (KPS) score at least 70%. Karnofsky Performance Status (KPS) greater than or equal to (>=) 70%. Karnofsky performance status (KPS) >=70% Karnofsky performance status (KPS) >= 60% Karnofsky performance status (KPS) >= 60% Participants must have a Karnofsky Performance Status (KPS) >= 60 Eastern Cooperative Group Performance (ECOG) or Karnofsky Performance Status (KPS) of 0-1 or >= 80%, respectively; if KPS is decreased due to myeloma, >= 70% is acceptable Patients must have a Karnofsky performance status (KPS; Appendix D) of ? 70% Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) of > 80% Have a Karnofsky performance status (KPS) >= 70 Participants must have a Karnofsky performance status (KPS) of >= 50 Karnofsky performance status (KPS) performance score >= 70% Karnofsky Performance Status (KPS) of at least 70% Subjects must have a Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) 70-100% Karnofsky performance status (KPS) of >= 70% at time of enrollment Karnofsky Performance Score (KPS) of ? 70% Patients must have a Karnofsky performance status (KPS) > 60 Karnofsky performance status of >= 80% on the modified Karnofsky performance status (KPS) tool Karnofsky performance status (KPS) 70-100 Karnofsky performance status (KPS) >= 60 Karnofsky performance score (KPS) >= 70% Patients must have a Karnofsky performance score (KPS) of >= 60 Karnofsky performance status (KPS) >= 60% All patients must have a Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) >= 80% Karnofsky performance score (KPS) >= 60% Karnofsky Performance Score (KPS)>=60. The patient must have a Karnofsky performance score (KPS) of >= 70% at the time of entry Karnofsky Performance Status (KPS) ?80% Patients must have a Karnofsky performance status (KPS) of >= 60 Karnofsky performance score (KPS) < 70% Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 70 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) >= 80% Karnofsky Performance Status (KPS) of ?70 Karnofsky performance status (KPS) >= 70% Karnofsky performance score (KPS) >= 70% Karnofsky performance status (KPS) greater than or equals to 70 The patient must have a Karnofsky performance status (KPS) of >= 80% Karnofsky performance status (KPS) > 70% Karnofsky performance status (KPS) >= 70% Karnofsky Performance Status (KPS) > 50% Karnofsky performance status (KPS) < 70 Karnofsky performance status (KPS) 0-2 Subject has a Karnofsky performance status (KPS) ? 70%. Karnofsky performance status (KPS) score >= 70 Have a Karnofsky Performance Score (KPS) equal to or greater than 70 Karnofsky Performance Score (KPS) ? 70%. Karnofsky Performance Status (KPS) score ? 70 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) >= 50 Karnofsky performance status (KPS) score >= 40 Karnofsky performance status (KPS) >= 70% Karnofsky performance status (KPS) score ? 70%. Patient has Karnofsky performance status (KPS) ?70%. Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) of >= 60% at study entry Karnofsky performance status (KPS) of >= 70% Karnofsky performance status (KPS) of >= 70% Karnofsky Performance Score (KPS) ? 70% Karnofsky performance status (KPS) > 70 Performance status KPS 70 or more. Karnofsky performance status (KPS) >= 70 % Karnofsky performance status score (KPS) >= 60 Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 60% PATIENT ONLY: Karnofsky performance status (KPS) of 80 or above Karnofsky performance status (KPS) greater than 60. PATIENTS ONLY: Karnofsky performance status (KPS) of 80 or above Karnofsky performance status (KPS) >= 60% Have a Karnofsky performance status (KPS) score of 60% (be able to care for most of the personal needs) Karnofsky performance score (KPS) >= 70% Karnofsky performance status (KPS) performance status of 60% or greater Karnofsky performance status (KPS) >= 60 Karnofsky performance status (KPS) >= 70 Karnofsky Performance Status (KPS) ? 70% Karnofsky performance status (KPS) >= 70% Group I: Karnofsky performance score (KPS) >= 80 Group II: Karnofsky performance score (KPS) >= 80 Group III: Karnofsky performance score (KPS) >= 80 Patient must have Karnofsky performance status (KPS) of at least 60 Karnofsky Performance Status (KPS) >= 70 Karnofsky performance status (KPS) score >= 60 Karnofsky Performance Status (KPS) score ? 70%