Reliable telephone access so as to be able to receive calls from an interactive voice response (IVR) system (only applicable to patients participating in the optional symptom burden assessment portion) Refuse or unable to perform telephone or video conferences with research coordinator Access to a telephone Have an address and telephone number where he/she may be reached Have a working telephone Part 1: be willing to engage in follow-up telephone calls with a research nurse Part 1: have telephone access so they can be contacted by the research nurse Ability to comprehend and respond to questions using a telephone keypad Reliable telephone access to receive calls from an interactive voice response system (IVR) (only applicable to patients who will participate in optional symptom burden assessment) Must have access to a telephone; if a patient does not have access to a phone or has difficulty paying for minutes for a mobile phone, the research team should contact the Wake Forest investigators or site coordinators to arrange for assistance The patient must have access to a telephone and phone number where they can be reached Has a working telephone number Must have telephone Daily access to a telephone AIM 2: Must have an active telephone number Have access to a telephone Do not have contact information (e.g., address, telephone number) Telephone or email access and agreement to engage with the research personnel via phone or email Patient must be willing to engage in telephone follow up with research staff Patient must have telephone access to be contacted by the research staff Reachable consistently by telephone; and Not reachable consistently by telephone; and Patient willing to keep a daily fatigue diary, engage in daily telephone follow up with a nurse and after 7 days of treatment either return for a follow up visit or this can be done over the telephone Have a mailing address and working telephone number Telephone access Participant must have access to a working telephone and be willing and available to participate by this modality as needed Patient willing to keep a daily diary, engage in telephone follow up with a nurse Patient must have telephone access to be contacted by the research nurse Participant must have telephone access and agree to engage with telephone access with the research personnel Can be reached by telephone Patients: Telephone access Be willing to engage in follow-up telephone calls with a research nurse/coordinator Have telephone access to be contacted by the research nurse/coordinator Have access to a telephone Patients must have working telephone, mobile or land line Difficulty hearing on the telephone Patients who have a recent telephone number in their HC records Have telephone service Can be reached by telephone or email Must be reachable by telephone Functioning telephone number. Have an address and telephone number where he/she may be reached. Have an address and telephone number where they may be reached Lack telephone access Functioning telephone Patients with major psychiatric illnesses who may not be able to fully participate in the brief telephone counseling (i.e. participants with schizophrenia) Have an address and telephone number where they may be reached Have a valid telephone number and email address Healthy post-pubescent teens with access to a telephone Have access to a telephone or mobile phone Homeless individuals (address, telephone etc.) Lack access to a telephone Working telephone number Have access to a telephone No access to a telephone PHASE II: Must indicate telephone and internet access Participants must have access to a telephone Accessible geographically and by telephone Individuals that do not have access to a working telephone Functioning telephone Able to provide data through questionnaires and by telephone Access to a telephone Has access to telephone Must have telephone access and agree to engage with research personnel using telephone (PCS study) Mothers must have ready and consistent access to a telephone to participate in the trial's assessments