Patients must have total bilirubin =< 1.5 x IULN Patients must have total bilirubin =< 2.5 x IULN Direct bilirubin =< 1.5 x IULN (=< 5 x IULN if secondary to lymphoma) within 28 days prior to registration Patients must have total bilirubin =< 2.0 x IULN within 14 days prior to registration Total bilirubin =< 2.0 x IULN within 14 days prior to registration Patients must have bilirubin =< 2 x IULN within 7 days prior to registration (unless the bilirubin is primarily unconjugated) Total bilirubin =< 1.5 x the IULN Serum total bilirubin =< 1.5 x IULN OR direct bilirubin =< IULN for patients with total bilirubin > 1.5 x IULN Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) OR direct bilirubin =< IULN for patients with total bilirubin > 1.5 x IULN Bilirubin =< 1.5 x IULN Bilirubin 1.5-2 x IULN Total bilirubin =< 1.5 x international upper limit of normal (IULN) OR direct bilirubin =< IULN for patients with total bilirubin > 1.5 x IULN Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) OR direct bilirubin =< IULN for patients with total bilirubin > 1.5 x IULN ARM B COHORT 3: Total bilirubin =< 1.5 x IULN ARM C COHORT 4: Total bilirubin =< 2 X IULN Total bilirubin < 3 x IULN Total bilirubin =< 1.5 x IULN Total bilirubin =< 1.5 x IULN Total bilirubin =< 1.5 x IULN Total bilirubin =< 1.5 x IULN Total bilirubin < 1.5 x IULN REGISTRATION #2 - PRIOR TO CONSOLIDATION CHEMOTHERAPY: Total bilirubin =< IULN Total bilirubin =< 1.5 x IULN Total bilirubin =< 1.5 x IULN within 14 days prior to Step 3 registration Total bilirubin =< IULN; or total bilirubin =< 3.0 x IULN or direct bilirubin =< 1.5 ULN in patients with well documented Gilbert’s syndrome Total bilirubin =< 1.5 x IULN Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) OR direct bilirubin =< IULN for patients with total bilirubin > 1.5 x IULN Total bilirubin >= 2 x IULN