Patient must have adequate nutritional status with Body Mass Index (BMI) > 18 kg/m^2 and body weight of > 40 kg with serum albumin > 3 g/dL. BMI >= 27 kg/m^2 documented within 56 days prior to study registration; the most recent body mass index (BMI) obtained must be used for eligibility; if most recent BMI is < 27 then the patient is not eligible to enroll BMI 18 to 32 kg/m2. Patient must have adequate nutritional status with Body Mass Index (BMI) > 18 kg/m^2 and body weight of > 40 kg with serum albumin > 3 g/dL. BMI >= 25 kg/m^2 Body mass index (BMI) <18.5 or >35 kg/m2. Have initial body mass index (BMI) >= 27.0 kg/m^2 and =< 40 kg/m^2 Patient’s body mass index must be 30 kg/m^2 or higher The donor has a BMI of more than 18.5 and less than 35.0 kg/m2. Has BMI > 34.9 kg/m2. Has BMI > 34.9 kg/m2 Body mass index > 40 kg/m² Body mass index (BMI) > 40 kg/m^2 Are overweight or obese with the following criteria (determined by study team at eligibility screening): body mass index (BMI) > 25 kg/m^2 (calculated using height and weight; an upper limit BMI will not be set; we will rely on obtaining physicians’ clearance to assess full eligibility) or body fat > 30% (estimated by bioelectrical impedance), and waist circumference > 35 in Body mass index (BMI) >= 30 kg/m^2 BMI =< 29.9 kg/m^2 Body mass index (BMI) >= 36 kg/m^2 Body mass index (BMI) >= 20 kg/m^2 Body mass index (BMI) < 30 kg/m^2 Body mass index (BMI) (26 - 40 kg/m^2) Patient is obese (body mass index [BMI] >= 30 kg/m^2) Body mass index (BMI) >= 25 kg/m^2; and Body mass index (BMI) < 18.5 or > 35 kg/m^2 will be excluded Body mass index (BMI) >= 22 kg/m^2 BMI < 25 kg/m^2 Obese – defined as a body mass index (BMI) >= 35 kg/m^2 as calculated in the Epic computer record Body mass index (BMI) of 25-33 kg/m^2 Body mass index (BMI) >= 25 kg/m^2 Body mass index (BMI) between 18 and 35 kg/m^2 Body mass index (BMI) greater than or equal to 30 kg/m^2 BMI less than 30 kg/m^2 Body mass index (BMI) 30- < 45 kg/m^2 Body mass index (BMI) > 30 kg/m^2 BMI < 30 kg/m^2 Body-mass index less than 18.5 (kg/m^2) Phase 2 only: be overweight or obese (i.e., have a body mass index [BMI] > or = 25 kg/m^2) Obesity (body mass index [BMI] >= 30 kg/m^2) Patients with body mass index (BMI) < 20 kg/m^2 Body mass index (BMI) < 18.5 Kg/m^2 Body Mass Index (BMI) >= 30 kg/m^2. Has a current measured BMI less than 30 kg/m^2. Body mass index (BMI) 25-40 kg/m^2 Body mass index (BMI) > 30 kg/m^2; women with a BMI > 45 kg/m^2 must be age < 60 and ability to perform physical activity must be confirmed Body mass index (BMI) 30-45 kg/m^2 Body mass index (BMI) > or equal to 25 kg/m^2 BMI 25-40 kg/m^2 Body mass index (BMI): < 36 kg/m^2 Have a body mass index (BMI) of 25 kg/m^2 or greater and weight =< 400 lbs Body mass index (BMI) 25-45 kg/m^2 Body mass index (BMI) < 40 kg/m^2 Body mass index (BMI) above 45 kg/m^2 Body mass index (BMI) >= 25 kg/m^2 Have a body mass index (BMI) between 30.0 kg/m^2 and 45.0 kg/m^2 Body mass index (BMI) >= 24 kg/m^2 Have a body mass index (BMI) of 25 kg/m^2 or greater Body mass index (BMI) > or = 30 kg/m^2 Overweight or obese (body mass index [BMI] >= 25.0 kg/m^2) BMI ? 24 kg/m2. Body mass index (BMI) overweight-obese: 25.0 - 40 kg/m^2 Body mass index < 35 kg/m^2 Body mass index (BMI) < 35 kg/m^2 Body mass index (BMI) 25-45 kg/m^2 Body mass index (BMI) greater than or equal to 40 or less than or equal to 17 kg/m^2 at screening visit Initial body mass index (BMI) >= 30.0 kg/m^2 and < 40 kg/m^2 Body mass index is >= 25 kg/m^2 Patients with body mass index greater than 40 kg/m^2