Hemoglobin (Hgb) >= 9 g/dl Hemoglobin (Hgb) > 8.0 g/dL =< 2 weeks prior to randomization Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (HgB) >= 9.0 gr/dL Hemoglobin (Hgb) >= 8.5 Hemoglobin (Hgb) >= 8 g/dl Hemoglobin (Hgb) ? 8 g/dL Hemoglobin (Hgb) ? 80 g/L Hemoglobin (Hgb) < 9 g/dL Hemoglobin (Hgb) ? 9 g/dL; Hemoglobin (Hgb) > 10 g/dL within 14 days of starting cycle 1 day 1 treatment Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (HGB) >= 9 g/dL Hemoglobin (HgB) > 8.0 Hemoglobin (Hgb) > 8.0 Hemoglobin (Hgb) ? 8.0 g/dL, stable for ? 1 week Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) > 9 g/dL, at the screening visit Hemoglobin (Hgb) >= 10.0 g/dL Hemoglobin (Hgb) <9 g/dL Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) > 9 g/dL. INCLUSION - TREATMENT: Hemoglobin (Hgb) ? 9.0 g/dl Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Anemia (hemoglobin [Hgb] < 10 g/dL) Hemoglobin (Hgb) >= 9 g/dL. Hemoglobin (Hgb) >= 8.5 g/dl Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (HgB) >= 9 g/dL compatible for surgery Hemoglobin (HgB) < 10 g/dL Hemoglobin (Hgb) > 8 g/dL Hemoglobin (Hgb) ? 9.0 g/dL Hemoglobin (Hgb) =< 10.0 or Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 9 g/dL. Hemoglobin (Hgb) < 8 mg/dl Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) >= 9 g/dL (within 16 days before starting therapy) Hemoglobin (HGB) >= 10 g/dl Hemoglobin (Hgb) > 8.0 g/dL Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) >= 9 g/dl Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 10 g/dl within 30 days of enrollment to study Hemoglobin (Hgb) > 8.5 g/dL Hemoglobin (Hgb) > 9.0 g/dL, within 14 days prior to treatment Hemoglobin (Hgb) >= 9 g/dL. Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) ? 9 g/dL Hemoglobin (HGB) < 8 g/dL Hemoglobin (Hgb) >= 8 gr/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) > 8 g/dl Hemoglobin (Hgb) ? 90 g/L (9 g/dL). Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) >= 8 g/dL Within 3 months of registration: Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) > 10 within 30 days of consent Hemoglobin (Hgb) > 9 within 45 days of consent Hemoglobin (HgB) >= 9 g/dL AT THE TIME OF INFUSION: Hemoglobin (Hgb) ? 8.0 Hemoglobin (Hgb) >= 9 g/dL TREATMENT: Hemoglobin (Hgb) > 8.0 g/dL Hemoglobin (Hgb) <9 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 8 Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) greater than 10 g/L Hemoglobin (Hgb) > 9 g/dL Within 30 days of first vaccination: Hemoglobin (Hgb) >= 10 g/dl Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (HgB) > 8.0 Hemoglobin (Hgb) >= 9 Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) >= 10 g/dl Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) >= 8.5 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 10 g/dl Hemoglobin (HGB) >= 9 g/dL Hemoglobin (Hgb) < 8 g/dL Hemoglobin (Hgb) > 8.0 Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (Hgb) >= 9 g/dl Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (HgB) >= 9 g/dL for mono-therapy Hemoglobin (Hgb) ? 9 g/dL Hemoglobin (Hgb) ? 9 g/dL Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) less than or equal to 8 g/dL Hemoglobin (Hgb) > 8 g/dL Hemoglobin (HgB) > 9.0 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) < 9 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) > 10 Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) >= 8.0 g/dL Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (Hgb) > 8.0 Anemia (hemoglobin [Hgb] < 10 g/dL) Hemoglobin (Hgb) ? 90 g/L, Hemoglobin (Hgb) ? 9.0 g/dL Hemoglobin (Hgb) ? 9 g/dL Hemoglobin (Hgb) ? 9 g/dl Hemoglobin (Hgb) ? 9 g/dL. Hemoglobin (Hgb) ? 9 g/dl Hemoglobin (HgB) >= 9 Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) > 8.0 g/dL Hemoglobin (Hgb) > 8.0 Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (HgB) ?9 g/dL. Hemoglobin (Hgb) >= 10 g/dL (within 16 days before starting therapy) Hemoglobin (Hgb) > 9 Hemoglobin (Hgb) > 9 g/dl Hemoglobin (HGB) >= 10 g/dl Hemoglobin (Hgb) > 10 g/dL Hemoglobin (Hgb) > 10 g/dL Hemoglobin (HgB) >= 10.0 g/dL Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) >= 9.0 g/dL hemoglobin (Hgb) > 9.9 g/dL Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (HGB) >= 8 g/dL Hemoglobin (Hgb) >= 10 g/dl Hemoglobin (Hgb) >= 10 g/dL (within 16 days before starting therapy) Hemoglobin (Hgb) >= 8 g/dl Hemoglobin (Hgb) >= 8.5 g/dL Hemoglobin (Hgb) >= 9 g/dl Hemoglobin (Hgb) ? 10 g/dl Hemoglobin (Hgb) ? 10 g/dl. Hemoglobin (Hgb) ? 9.0 g/dL Hemoglobin (Hgb) < 7.0 Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (hgb) =< 10.0 or Hemoglobin (HgB) >= 9.0 mg/dL Hemoglobin (Hgb) > 8.0 g/dl Hemoglobin (Hgb) >= 9g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9 g/dl Hemoglobin (Hgb) ? 9.0 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) > 8.0 Hemoglobin (Hgb) ? 9 g/dL. Hemoglobin (Hgb) < 9 g/dL Hemoglobin (Hgb) ?10 g/dL Hemoglobin (HgB) > 9.0 g/dL Hemoglobin (Hgb) >= 10 g/dL Hemoglobin (Hgb) >= 10 g/dL Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (Hgb) ? 9.0 g/dL SELUMETINIB ARM: Hemoglobin (Hgb) < 9.0 g/dL Hemoglobin (HgB) >= 8.0 g/dL Hemoglobin (Hgb) >= 9 g/L Hemoglobin (Hgb) >= 10 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) ? 9.0 g/dL; Hemoglobin (Hgb) ? 9 g/dL. Hemoglobin (HgB) >= 9 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) ? 9 g/L Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) >= 9.0 g/dL Hemoglobin (Hgb) ? 9 g/dL. Hemoglobin (Hgb) ? 8.0 g/dL at Baseline (within 24 hours prior to surgical procedure). Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) ? 8.0 g/dL Hemoglobin (Hgb) ? 9 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (HgB) > 8.5 g/dL Hemoglobin (Hgb) ?9.5 g/dl Hemoglobin (HgB) > 9.0 g/dL Hemoglobin (Hgb) >= 9.0 g/dl Hemoglobin (Hgb) > 9.0 gms/dl Hemoglobin (Hgb) > 8.0 g/dl Hemoglobin (Hgb) >= 8 g/dL Hemoglobin (Hgb) > 9 g/dL Hemoglobin (Hgb) >= 9 g/dL Severe anemia with hemoglobin (HGB) < 10 Hemoglobin (Hgb) ? 9.0 g/dL Hemoglobin (HgB) >= 9.0 g/dL Hemoglobin (Hgb) ?>= 8.0 g/dL Hemoglobin (Hgb) >= 9.0 Hemoglobin (Hgb) >= 9 g/dL Hemoglobin (Hgb) > 8.0 Hemoglobin (Hgb) > 8.0 g/dL Hemoglobin (Hgb) >= 10 g/dl within 90 days of enrollment Hemoglobin (Hgb) >= 8.0g/dL Hemoglobin (Hgb) ? 8 g/dL. Hemoglobin (Hgb) ? 10 g/dl Hemoglobin (Hgb) > 8.0 Hemoglobin (hgb) > 10 G/dL Hemoglobin (HgB) > 9 mg/dL