Subjects must have adequate renal function defined as a serum creatinine based on age/gender
Renal insufficiency with serum creatinine > 1.6
Adequate renal function as evidenced by a serum creatinine =< 1.5 x upper limit of normal (ULN)
Adequate renal function as evidenced by a serum/plasma creatinine < 1.5 x ULN
Renal: Serum creatinine ? 1.5 times ULN.
Renal: creatinine ? 2x of ULN for age
Have adequate renal function (Serum creatinine <3 mg/dL).
Abnormal renal function (serum creatinine > 2 x ULN)
Acceptable renal function: *Serum creatinine ? 1.5 times the ULN.
Adequate renal function with serum creatinine ?2.5 mg/dL
Patients with impaired renal function as evidenced by creatinine-clearance < 50% for age, weight, height or serum creatinine > 2 x upper normal limit or dialysis-dependent
Renal function: serum creatinine ? 1.5 times the ULN range of each institution.
Adequate renal function including creatinine < 2 unless related to the disease
Adequate renal function: serum creatinine less than 1.5 x upper limit of normal (ULN)
Renal function: Creatinine ? 2.0 × ULN
Renal function (creatinine <1.5 × ULN)
Renal function (creatinine <1.5 × ULN)
Adequate renal function with creatinine (Cr) =< 2.5 mg/dL
Adequate renal function assessed by: serum creatinine ? 1.5 × ULN
Adequate renal function: creatinine ?1.5 x ULN
Preservation of renal function, serum creatinine did NOT increase by more than 2 fold above the normal range
Preservation of renal function, serum creatinine did NOT increase by more than 2 fold above the normal reference range
Renal function: preservation of renal function, serum creatinine did NOT increase by more than 2 fold above the normal reference range
Renal function criteria: preservation of renal function, serum creatinine did NOT increase by more than 2 fold above the normal reference range
Subjects must have adequate renal function defined as: Serum creatinine based on age/gender.
Patients must have adequate Hematologic function(ANC ? 1,500/mcl and platelets ? 100,000/mcl), Renal function(serum creatinine ? ULN or calculated creatinine clearance ? 60 mL/min), Hepatic function(serum bilirubin ? 1.5 x ULN and AST ? 2.5 x ULN and ALT? 2.5 x ULN)
Patient must have adequate renal function as defined by serum creatinine < -2.5 mg/dl obtained within 28 days prior to registration
Creatinine =< 1.2 mg/dl (urinary diversion is permitted to improve renal function)
Adequate renal function defined as serum creatinine equal to or less than 1.5 x upper limit of normal (ULN)
Renal function: Serum creatinine >1.5x ULN
Renal insufficiency or serum creatinine >1.5 X ULN at screening.
Patients must have adequate renal function defined as age-adjusted serum creatinine =< 1.5 x normal for age
With impaired renal function as evidenced by creatinine-clearance < 50% for age, weight, height or serum creatinine > 2 x upper limit of normal or dialysis-dependent
Adequate renal function: serum creatinine =< 1.5 x ULN
Renal Function (creatinine clearance or serum creatinine):
Subjects must have adequate renal function as evidenced by a serum creatinine of <2.0 mg/dl.
Renal: Creatinine > 1.5x ULN
Renal: Creatinine > 1.5x ULN.
Renal: Creatinine > 1.5x ULN
Adequate renal function: serum creatinine <2.5mg/dL
Renal function: • Creatinine less than or equal to 1.5 x ULN
Renal: Serum creatinine 1.5 times ULN.
Adequate renal function defined as serum creatinine ?3 times the institutional upper limit of normal (ULN)
Adequate renal function (defined as serum creatinine =< 1.5 X ULN)
Has adequate renal function defined as serum creatinine or ? 1.5 × ULN and creatinine clearance or ? 40 ml/min.
Patient has adequate renal function defined as: Serum creatinine ?1.5 the institutional ULN
Adequate renal function, defined as serum creatinine ?1.5x ULN
Patients with normal renal function according to MD Anderson testing standards and no prior renal disease [screening cut off for serum creatinine < 1.5 times ULN]
Renal Status (within 30 days prior to randomization): a) Creatinine no greater than 1.5 times ULN
Patients must have adequate renal function (creatinine < 1.5 mg/dL) before starting therapy and the test must be performed within 14 days prior to registration
Adequate renal function, defined as serum creatinine ? 2.0 times ULN and creatinine clearance > 50 mL/min
Adequate renal function, defined by serum creatinine ? 1.5 x ULN.
Patients must have adequate renal function as defined by a serum creatinine =< 1.5 times ULN within one week prior to treatment
Has adequate renal function as evidenced by serum creatinine ?2.5 × the upper limit of normal (ULN) for the reference lab;
Patients must have an adequate renal function as documented by serum creatinine less than or equal to 2.0 mg/dL.
Patient must have adequate renal function documented by a serum creatinine of ? 1.5 times the ULN for the reference lab.
Renal function: creatinine ? 1.5 x ULN
Adequate renal function, defined as serum creatinine ? 1.5x ULN
Adequate renal function as demonstrated by serum creatinine ? 1.5 x ULN, or 24-hr urine creatinine clearance calculation >60 mL/min
Creatinine (renal function) =< 1.5 X ULN
Abnormal renal function tests (creatinine > 1.5)
Renal: Serum creatinine less than or equal to 1.5 times ULN.
Renal Function Creatinine >1.5 mg%
Hepatic and renal function meeting the strata as outlined below; nota bene (NB): patients must fulfill both total bilirubin and serum glutamic-oxaloacetic transaminase (SGOT)/aspartate aminotransferase (AST) criteria and creatinine function to be included in a group; however, if a patient’s total bilirubin and SGOT/AST and creatinine levels indicate different groups, the patient may be enrolled in the indicated group with the greatest degree of liver dysfunction; all liver and renal function tests must be completed within 24 hours prior to the start of treatment; Note: patients on dialysis will not be eligible\r\n* Group A: hepatic function: normal function (bilirubin =< upper limit of normal [ULN]; AST =< ULN); renal function: normal function (creatinine clearance [CrCl] >= 60 mL/min) \r\n* Group B: hepatic function: normal function (bilirubin =< ULN; AST =< ULN); renal function: moderate dysfunction (CrCl >= 30 and < 60 ml/min)\r\n* Group C: hepatic function: normal function (bilirubin =< ULN; AST =< ULN); renal function: severe dysfunction (CrCl >= 15 and < 30 ml/min)\r\n* Group D: hepatic function: mild dysfunction D1: bilirubin =< ULN; AST > ULN, D2: bilirubin > ULN and =< 1.5 x ULN; any AST; renal function: normal function (creatinine clearance [CrCl] >= 60 mL/min)\r\n* Group E: hepatic function: mooderate dysfunction (bilirubin 1.5 x > ULN and =< 3 x ULN; any AST); renal function: normal function (creatinine clearance [CrCl] >= 60 mL/min)\r\n* Group F: hepatic function: severe dysfunction (bilirubin > 3 x ULN and up to investigator’s discretion; any AST); renal function: normal function (creatinine clearance [CrCl] >= 60 mL/min)
Patients must have normal renal function test and no prior renal disease; the screening cut off for serum creatinine is < 1.5 mg/dL
Abnormal renal function (serum creatinine level > 2X upper limit of normal [ULN]) as assessed by the central laboratory during screening.
Adequate renal function: serum creatinine ? 1.5x ULN;
Renal function: serum creatinine ?1.5 times the ULN range of each institution.
Subjects must have adequate renal function as defined by serum creatinine < 1.5 x upper limit of normal
The participant has adequate renal function as defined by serum creatinine less than or equal to 1.5 x the institutional ULN or creatinine clearance greater than or equal to 60 mL/min for participants with creatinine levels above the ULN.
The participant has adequate renal function as defined by serum creatinine less than or equal to 1.5 x the institutional ULN or creatinine clearance greater than or equal to 60 mL/min for participants with creatinine levels above the ULN.